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Prevalence of Antimicrobial Resistance in Acinetobacter calcoaceticus-baumannii Complex in a Saudi Arabian Hospital

Published online by Cambridge University Press:  02 January 2015

Jaffar A. Al-Tawfiq*
Affiliation:
Internal Medicine Services Division, Dhahran Health Center, Saudi Aramco Medical Services Organization, Saudi Aramco, Dhahran, Saudi Arabia
Thangiah X. Mohandhas
Affiliation:
Microbiology Laboratory, Dhahran Health Center, Saudi Aramco Medical Services Organization, Saudi Aramco, Dhahran, Saudi Arabia
*
PO Box 76, Room A-420B, Building 61, Dhahran Health Center, Saudi Aramco, Dhahran 31311, Saudi Arabia (jaffar.tawfiq@aramco.com)

Abstract

During the period from 1998 through 2004, a total of 476 isolates of Acinetobacter calcoaceticus-baumannii complex were recovered. The organism showed high rates of resistance to ampicillin (86% of isolates), cefoxitin (89%), and nitrofurantoin (89%). The rate of resistance to imipenem was 3%; to ticarcillin-clavulanic acid, 16.5%; to gentamicin, 26%; and to ceftazidime, 38%. Multidrug resistance was observed in 14%-35.8% of Acinetobacter species isolates.

Type
Concise Communications
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2007

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References

1.McDonald, LC. Trends in antimicrobial resistance in health care-associated pathogens and effect on treatment. Clin Infect Dis 2006;42(suppl 2):S65S71.Google Scholar
2.Crowe, M, Towner, K, Humphreys, H. Clinical and epidemiological features of outbreak of Acinetobacter infection in an intensive therapy unit. J Med Microbiol 1995;43:5562.Google Scholar
3.Bergogne-Berezin, E, Towner, KJ. Acinetobacter spp. as nosocomial pathogens: microbiological, clinical, and epidemiological features. Clin Microbiol Rev 1996;9:148165.Google Scholar
4.Mah, MW, Memish, ZA, Cunningham, G, Bannatyne, RM. Outbreak of Acinetobacter baumannii in an intensive care unit associated with tracheostomy. Am J Infect Control 2001;29:284288.CrossRefGoogle Scholar
5.National Committee for Clinical and Laboratory Standards (NCCLS). Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria that Grow Aerobically. Approved Standard. 6th ed. Wayne, PA: NCCLS; 2003: M7A6.Google Scholar
6.Eltahawy, AT, Khalaf, RM. Antibiotic resistance among gram-negative non-fermentative bacteria at a teaching hospital in Saudi Arabia. J Chemother 2001;13:260264.Google Scholar
7.Poirel, L, Menuteau, O, Agoli, N, Cattoen, C, Nordmann, P. Outbreak of extended-spectrum beta-lactamase VEB-l-producing isolates of Acinetobacter baumannii in a French Hospital. J Clin Microbiol 2003;41:35423547.Google Scholar
8.Wu, CJ, Lee, HC, Lee, NY, et al.Predominance of gram-negative bacilli and increasing antimicrobial resistance in nosocomial bloodstream infections at a university hospital in southern Taiwan, 1996-2003. J Microbiol Immunol Infect 2006;39:135143.Google Scholar
9.Ishii, Y, Alba, J, Kimura, S, Yamaguchi, K. Evaluation of antimicrobial activity of beta-lactam antibiotics by Etest against clinical isolates from 100 medical centers in Japan (2004). Diagn Microbiol Infect Dis 2006;55:143148.Google Scholar
10.Gales, AC, Jones, RN, Forward, KR, Linares, J, Sader, HS, Verhoef, J. Emerging importance of multi-drug resistant Acinetobacter species and Ste-notrophomonas maltophilia as pathogens in seriously ill patients: geographic patterns, epidemiological features, and trends in the SENTRY Antimicrobial Surveillance Program (1997-1999). Clin Infect Dis 2001;32(suppl 2):S104S113.Google Scholar
11.Cisneros, JM, Rodriguez-Bano, J, Fernandez-Cuenca, F, et al.Risk-factors for the acquisition of imipenem-resistant Acinetobacter baumannii in Spain: a nationwide study. Clin Microbiol Infect 2005;11:874879.Google Scholar
12.Thongpiyapoom, S, Narong, MN, Suwalak, N, et al.Device-associated infections and patterns of antimicrobial resistance in a medical-surgical intensive care unit in a university hospital in Thailand. J Med Assoc Thai 2004;87:819824.Google Scholar
13.Pfaller, MA, Sader, HS, Fritsche, TR, Jones, RN. Antimicrobial activity of cefepime tested against ceftazidime-resistant gram-negative clinical strains from North American hospitals: report from the SENTRY Antimicrobial Surveillance Program (1998-2004). Diagn Microbiol Infect Dis 2006;56:6368.Google Scholar
14.Mahmood, A, Karamat, KA, Butt, T. Neonatal sepsis: high antibiotic resistance of the bacterial pathogens in a neonatal intensive care unit in Karachi. J Pak Med Assoc 2002;52:348350.Google Scholar
15.Hart, CA, Kariuki, S. Antimicrobial resistance in developing countries. BMJ 1998;317:647650.CrossRefGoogle ScholarPubMed