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Role of Matching in Case-Control Studies of Antimicrobial Resistance

Published online by Cambridge University Press:  02 January 2015

Elizabeth Cerceo ,
Ebbing Lautenbach ,
Darren R. Linkin ,
Warren B. Bilker  and
Ingi Lee
Elizabeth Cerceo
Affiliation:
Division of Infectious Diseases, Department of Medicine, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
Ebbing Lautenbach
Affiliation:
Division of Infectious Diseases, Department of Medicine, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania Department of Biostatistics and Epidemiology, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania Centers for Clinical Epidemiology and Biostatistics, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania Education and Research on Therapeutics, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
Darren R. Linkin
Affiliation:
Department of Biostatistics and Epidemiology, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania Education and Research on Therapeutics, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
Warren B. Bilker
Affiliation:
Department of Biostatistics and Epidemiology, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania Centers for Clinical Epidemiology and Biostatistics, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania Education and Research on Therapeutics, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
Ingi Lee*
Affiliation:
Division of Infectious Diseases, Department of Medicine, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania Centers for Clinical Epidemiology and Biostatistics, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania Education and Research on Therapeutics, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
*
Division of Infectious Diseases, Hospital of the University of Pennsylvania, 3400 Spruce Street, 3rd Floor, Silverstein Building, Suite E, Philadelphia, PA 19104) ingi.lee@uphs.upenn.edu)
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Abstract

Of 57 case-control studies of antimicrobial resistance, matching was used in 23 (40%). Matched variables differed substantially across studies. Of these 23 matched case-control studies, 12 (52%) justified the use of matching, and 9 (39%) noted the strengths or limitations of this approach. Analysis that accounted for matching was performed in only 52% of the case-control studies.

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 30 , Issue 5 , May 2009 , pp. 480 - 483
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2009

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References

1.Straelens, M. The epidemiology of antimicrobial resistance in hospital acquired infections: problems and possible solutions. BMJ 1998;317:652–654.CrossRefGoogle Scholar
2.Gold, H, Moellering, R. Antimicrobial-drug resistance. N Engl J Med 1996;335:1445–1453.CrossRefGoogle ScholarPubMed
3.Hennekens, CH, Buring, JE. Epidemiology in Medicine. Philadelphia, PA: Lippincott, Williams & Wilkins; 1987.Google Scholar
4.Woodward, M. Epidemiology: Study Design and Data Analysis. Boca Raton, FL: Chapman and Hall/CRC Press; 2005.Google Scholar
5.Malvy, D, Treilhaud, M, Bouee, S, et al. A retrospective, case-control study of acyclovir resistance in herpes simplex virus. Clin Infect Dis 2005;41:320–326.CrossRefGoogle ScholarPubMed
6.Lee, NE, Taylor, MM, Bancroft, E, et al. Risk factors for community-associated methicillin-resistant Staphylococcus aureus skin infections among HIV-positive men who have sex with men (published correction appears in Clin Infect Dis 2005;41:135). Clin Infect Dis 2005;40:1529–1534.CrossRefGoogle Scholar
7.Falagas, M, Mourtzoukou, E, Ntziora, F, Peppas, G, Rafailidis, P. Matching criteria in case-control studies on postoperative infections. J Hosp Infect 2008;69:101–113.CrossRefGoogle ScholarPubMed
8.Soriano, A, Martinez, JA, Mensa, J, et al. Pathogenic significance of methicillin resistance for patients with Staphylococcus aureus bacteremia. Clin Infect Dis 2000;30:368–373.CrossRefGoogle ScholarPubMed
9.Vasquez, J, Walker, E, Franzus, B, Overbay, B, Reagan, D, Sarubbi, F. The epidemiology of mupirocin resistance among methicillin-resistant Staphylococcus aureus at a veterans' affairs hospital. Infect Control Hosp Epidemiol 2000;21:459–464.CrossRefGoogle Scholar
10.Byers, K, Anglim, A, Anneski, C, et al. A hospital epidemic of vancomycin-resistant Enterococcus: risk factors and control. Infect Control Hosp Epidemiol 2001;22:140–147.CrossRefGoogle ScholarPubMed
11.Ho, P, Tse, W, Tsang, K, et al. Risk factors for acquisition of levofloxacin-resistant Streptococcus pneumoniae: a case-control study. Clin Infect Dis 2001;32:701–707.CrossRefGoogle ScholarPubMed
12.Lautenbach, E, Patel, J, Bilker, W, Edelstein, P, Fishman, N. Extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae: risk factors for infection and impact of resistance on outcomes. Clin Infect Dis 2001;32:1162–1171.CrossRefGoogle ScholarPubMed
13.Moroney, J, Fiore, A, Harrison, L, et al. Clinical outcomes of bacteremic pneumococcal pneumonia in the era of antibiotic resistance. Clin Infect Dis 2001;33:797–805.CrossRefGoogle ScholarPubMed
14.Tacconelli, E, Tumbarello, M, de Gaetano Donati, K, et al. Glycopeptide resistance among coagulase-negative staphylococci that cause bacteremia: epidemiological and clinical findings from a case-control study. Clin Infect Dis 2001;33:1628–1635.CrossRefGoogle ScholarPubMed
15.Harris, AD, Karchmer, TB, Carmeli, Y, Samore, MH. Methodological principles of case-control studies that analyzed risk factors for antibiotic resistance: a systematic review. Clin Infect Dis 2001;32:1055–1061.CrossRefGoogle ScholarPubMed
16.Carmeli, Y, Eliopoulos, G, Samore, M. Antecedent treatment with different antibiotic agents as a risk factor for vancomycin-resistant Enterococcus. Emerg Infect Dis 2002;8:802–807.CrossRefGoogle ScholarPubMed
17.Cetinkaya, Y, Falk, P, Mayhall, C. Effect of gastrointestinal bleeding and oral medications on acquisition of vancomycin-resistant Enterococcus fae-cium in hospitalized patients. Clin Infect Dis 2002;35:935–942.CrossRefGoogle ScholarPubMed
18.Lodise, T, McKinnon, P, Tam, V, Rybak, M. Clinical outcomes for patients with bacteremia caused by vancomycin-resistant Enterococcus in a level 1 trauma center. Clin Infect Dis 2002;34:922–929.CrossRefGoogle ScholarPubMed
19.Lonks, J, Garau, J, Gomez, L, et al. Failure of macrolide antibiotic treatment in patients with bacteremia due to erythromycin-resistant Streptococcus pneumoniae. Clin Infect Dis 2002;35:556–564.CrossRefGoogle ScholarPubMed
20.Hirakata, Y, Yamaguchi, T, Nakano, M, et al. Clinical and bacteriological characteristics of IMP-type metallo-β-lactamase-producing Pseudomonas aeruginosa. Clin Infect Dis 2003;37:26–32.CrossRefGoogle ScholarPubMed
21.Jernigan, J, Pullen, A, Flowers, L, Bell, M, Jarvis, W. Prevalence of and risk factors for colonization with methicillin-resistant Staphylococcus aureus at the time of hospital admission. Infect Control Hosp Epidemiol 2003; 24:409–414.CrossRefGoogle ScholarPubMed
22.Kang, C, Kim, S, Kim, D, et al. Risk factors for and clinical outcomes of bloodstream infections caused by extended-spectrum beta-lactamase-producing Klebsiella pneumoniae. Infect Control Hosp Epidemiol 2004;25:860–867.CrossRefGoogle ScholarPubMed
23.Paramythiotou, E, Lucet, J, Timsit, J, et al. Acquisition of multidrug-resistant Pseudomonas aeruginosa in patients in intensive care units: role of antibiotics with antipseudomonal activity. Clin Infect Dis 2004;38:670–677.CrossRefGoogle ScholarPubMed
24.Schwaber, M, Cosgrove, S, Gold, H, Kaye, K, Carmeli, Y. Fluoroquinolones protective against cephalosporin resistance in gram-negative nosocomial pathogens. Emerg Infect Dis 2004;10:94–99.CrossRefGoogle ScholarPubMed
25.Young, LS, Perdreau-Remington, F, Winston, LG. Clinical, epidemiologic, and molecular evaluation of a clonal outbreak of methicillin-resistant Staphylococcus aureus infection. Clin Infect Dis 2004;38:1075–1083.CrossRefGoogle ScholarPubMed
26.Abbo, A, Navon-Venezia, S, Hammer-Muntz, O, Krichali, T, Siegman-Igra, Y, Carmeli, Y. Multidrug-resistant Acinetobacter baumannii. Emerg Infect Dis 2005;11:22–29.CrossRefGoogle ScholarPubMed
27.Ernst, EJ, Raley, G, Herwaldt, LA, Diekema, DJ. Importance of control group selection for evaluating antimicrobial use as a risk factor for methicillin-resistant Staphylococcus aureus bacteremia. Infect Control Hosp Epidemiol 2005;26:634–637.CrossRefGoogle ScholarPubMed
28.Qavi, A, Segal-Maurer, S, Mariano, N, et al. Increased mortality associated with a clonal outbreak of ceftazidime-resistant Klebsiella pneumoniae: a case-control study. Infect Control Hosp Epidemiol 2005;26:63–68.CrossRefGoogle ScholarPubMed