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Surgical site infection rates are higher among elective colorectal surgery patients receiving non–beta-lactam–based antimicrobial prophylaxis: A retrospective chart review

Published online by Cambridge University Press:  22 August 2022

Alisha R. Fernandes Open the ORCID record for Alisha R. Fernandes [Opens in a new window] ,
Forough Farrokhyar Open the ORCID record for Forough Farrokhyar [Opens in a new window] ,
Cagla Eskicioglu Open the ORCID record for Cagla Eskicioglu [Opens in a new window] ,
William Ciccotelli  and
Shawn S. Forbes Open the ORCID record for Shawn S. Forbes [Opens in a new window]
Alisha R. Fernandes*
Affiliation:
Department of Surgery, Hamilton Health Sciences, Hamilton, Ontario, Canada
Forough Farrokhyar
Affiliation:
Department of Surgery, McMaster University, Hamilton, Ontario, Canada Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada
Cagla Eskicioglu
Affiliation:
Department of Surgery, Hamilton Health Sciences, Hamilton, Ontario, Canada Department of Surgery, McMaster University, Hamilton, Ontario, Canada Department of Surgery, St Joseph’s Healthcare Hamilton, Hamilton, Ontario, Canada
William Ciccotelli
Affiliation:
Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada Infectious Diseases and Medical Microbiology, Grand River Hospital, Kitchener, Ontario, Canada
Shawn S. Forbes
Affiliation:
Department of Surgery, Hamilton Health Sciences, Hamilton, Ontario, Canada Department of Surgery, McMaster University, Hamilton, Ontario, Canada
*
Author for correspondence: Dr. Alisha Fernandes, E-mail: alisha.fernandes@medportal.ca
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Abstract

We compared the odds of acquiring surgical site infection (SSI) for clean-contaminated colorectal surgeries between intravenous β-lactam–based prophylaxis (BLP) versus alternative antimicrobial prophylaxis (AAP). We calculated the odds of acquiring an SSI using logistic regression; adjusted odds ratios (ORs) with 95% confidence intervals (CIs) are reported. Increased odds of SSI were detected with AAP versus BLP (OR, 2.15; 95% CI, 1.33–3.50; P = .002).

Type
Original Article
Information
Infection Control & Hospital Epidemiology , Volume 44 , Issue 6 , June 2023 , pp. 881 - 884
Copyright
© The Author(s), 2022. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

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Footnotes

PREVIOUS PRESENTATION. Preliminary data were presented as a poster at the Canadian Surgery Forum on September 14, 2017, in Victoria, Canada.

References

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