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To treat or not to treat: Clostridioides difficile infection (CDI) guidelines, diagnostic algorithms, and CDI reporting

Published online by Cambridge University Press:  18 May 2023

Dale N. Gerding Open the ORCID record for Dale N. Gerding [Opens in a new window]
Dale N. Gerding*
Affiliation:
Edward Hines Jr. Veterans’ Affairs Hospital, Hines, Illinois
*
Corresponding author: Dale N. Gerding; Email: Dale.gerding2@va.gov
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Abstract

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Type
Commentary
Information
Infection Control & Hospital Epidemiology , Volume 44 , Issue 9 , September 2023 , pp. 1369 - 1370
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Creative Commons
This is a work of the US Government and is not subject to copyright protection within the United States. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America.
Copyright
© Edward Hines Jr VA Hospital, 2023

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References

McDonald, LC, Gerding, DN, Johnson, S, et al. Clinical practice guidelines for Clostridium difficile infection in adults and children: 2017 update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA) Clin Infect Dis 2018;66:987–994.10.1093/cid/ciy149CrossRefGoogle Scholar
Hecker, MT, Son, AH, Zuccaro, P, Conti, J, Donskey, CJ. Real-world evaluation of a 2-step testing algorithm for Clostridioides difficile infection. Infect Control Hosp Epidemiol 2023. doi: 10.1017/ice.2022.313.CrossRefGoogle Scholar
Guh, A, Winston, LG, Johnston, H, et al. Potential underreporting of treated patients using a Clostridioides difficile testing algorithm that screens with a nucleic acid amplification test. Open Forum Infect Dis 2022;9 suppl 2:fac492.131.CrossRefGoogle Scholar
Guh, AY, Hatfield, KM, Winston, LG, et al. Toxin enzyme immunoassays detect Clostridioides difficile infection with greater severity and higher recurrence rates. Clin Infect Dis 2019;69:1667–1674.CrossRefGoogle ScholarPubMed
Guh, AY, Mu, Y, Winston, LG, et al. Trends in US burden of Clostridioides difficile infection and outcomes. N Engl J Med 2020;382:1320–1330.10.1056/NEJMoa1910215CrossRefGoogle ScholarPubMed
Kociolek, LK, Gerding, DN, Carrico, R, et al. Strategies to prevent Clostridioides difficile infections in acute-care hospitals: 2022 update. Infect Control Hosp Epidemiol 2023;44:527–549.CrossRefGoogle ScholarPubMed
Alonso, CD, Kelly, CP, Garey, KW, et al. Ultrasensitive and quantitative toxin measurement correlates with baseline severity, severe outcomes, and recurrence among hospitalized patients with Clostridioides difficile infection. Clin Infect Dis 2022;74:2142–2149.CrossRefGoogle ScholarPubMed
Pollock, NR, Banz, A, Chen, X, et al. Comparison of Clostridioides difficile stool toxin concentrations in adults with symptomatic infection and asymptomatic carriage using an ultrasensitive quantitative immunoassay. Clin Infect Dis 2019;68:78–86.Google ScholarPubMed