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Transmission of Drug-Resistant HIV After an Occupational Exposure Despite Postexposure Prophylaxis With a Combination Drug Regimen

Published online by Cambridge University Press:  02 January 2015

Elise M. Beltrami ,
Chi-Cheng Luo ,
Nicolas de la Torre  and
Denise M. Cardo
Elise M. Beltrami*
Affiliation:
Prevention and Evaluation Branch, Division of Healthcare Quality Promotion, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia
Chi-Cheng Luo
Affiliation:
HIV Immunology and Diagnostics Branch, Division of AIDS, STD, and TB Laboratory Research, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia
Nicolas de la Torre
Affiliation:
HIV Immunology and Diagnostics Branch, Division of AIDS, STD, and TB Laboratory Research, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia
Denise M. Cardo
Affiliation:
Prevention and Evaluation Branch, Division of Healthcare Quality Promotion, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia
*
Centers for Disease Control and Prevention, Mailstop E-68, 1600 Clifton Road, Atlanta, GA30333
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Abstract

We documented a case of occupational human immunodeficiency virus (HIV) despite postexposure prophylaxis (PEP) with a combination drug regimen after percutaneous injury with a needle from a sharps disposal container in the hospital room of an HIV-infected patient. This failure of PEP with a combination drug regimen may have been related to antiretroviral drug resistance, other factors, or both. This case highlights the importance of preventing injury to prevent occupational transmission of HIV.

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 23 , Issue 6 , June 2002 , pp. 345 - 348
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2002

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