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Trends in beta-hemolytic Streptococcus infections within Veterans’ Affairs medical centers from 2009 to 2018

Published online by Cambridge University Press:  06 September 2021

GiGi Yam ,
Bethany A. Wattengel ,
Michael T. Carter ,
John A. Sellick ,
Alan J. Lesse  and
Kari A. Mergenhagen
GiGi Yam
Affiliation:
Department of Pharmacy, Western NY VA Healthcare System, Buffalo, New York
Bethany A. Wattengel
Affiliation:
Department of Pharmacy, Western NY VA Healthcare System, Buffalo, New York
Michael T. Carter
Affiliation:
Department of Pharmacy, Western NY VA Healthcare System, Buffalo, New York
John A. Sellick*
Affiliation:
Department of Infectious Diseases, Western NY VA Healthcare System, Buffalo, New York University at Buffalo, Jacobs School of Medicine, Buffalo, New York
Alan J. Lesse
Affiliation:
Department of Infectious Diseases, Western NY VA Healthcare System, Buffalo, New York University at Buffalo, Jacobs School of Medicine, Buffalo, New York
Kari A. Mergenhagen*
Affiliation:
Department of Pharmacy, Western NY VA Healthcare System, Buffalo, New York
*
Author for correspondence: Kari A. Mergenhagen, E-mail: Kari.Mergenhagen@va.gov. Or John A. Sellick, E-mail: John.Sellick@va.gov
Author for correspondence: Kari A. Mergenhagen, E-mail: Kari.Mergenhagen@va.gov. Or John A. Sellick, E-mail: John.Sellick@va.gov
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Abstract

Objective:

The purpose of this study was to describe the recent trends of invasive and noninvasive β-hemolytic Streptococcus cultures in the Veterans’ Affairs (VA) cohort from 2009 to 2018.

Design:

Retrospective cohort study from January 1, 2009, to January 1, 2019.

Setting:

Veterans’ Affairs medical centers.

Patients or participants:

All patients aged 18 years and older with cultures positive for β-hemolytic Streptococcus at a VA facility were included in the study.

Intervention(s):

Data were retrieved from the VA Corporate Data Warehouse using structure query language through the SQL Server Management Studio software.

Results:

Between 2009 and 2018, there were 40,625 patients with cultures with β-hemolytic Streptococcus. The median age was 64 years (interquartile range [IQR], 55–71) and the median Charlson comorbidity index was 4 (IQR, 2–7). Distributions for each type of β-hemolytic Streptococcus based on site of culture are provided. The 30-day all-cause mortality rate from all invasive β-hemolytic Streptococcus cases was 2.3%, and the 90-day all-cause mortality rate was 4.4%. The 30- and 90-day all-cause mortality rates for Streptococcus cases were higher for group A (3.9% and 6.1% respectively) and for groups C and G combined (3.2% and 6.1%, respectively) than for group B (2.0% and 4.0%, respectively).

Conclusions:

Trends of cultures for invasive and noninvasive β-hemolytic Streptococcus suggest an association with disease and mortality. The burden associated with β-hemolytic Streptococcus infections should not be underestimated.

Type
Original Article
Information
Infection Control & Hospital Epidemiology , Volume 42 , Issue 11 , November 2021 , pp. 1356 - 1360
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Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

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