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Variability of surgical prophylaxis in penicillin-allergic children

Published online by Cambridge University Press:  11 December 2018

David F. Butler ,
Brian R. Lee ,
Sarah Suppes ,
Tracy Sandritter ,
Jason G. Newland ,
Lory Harte  and
Jennifer L. Goldman
David F. Butler*
Affiliation:
Department of Pediatrics, Children’s Mercy Hospital, Kansas City, Missouri
Brian R. Lee
Affiliation:
Department of Pediatrics, Children’s Mercy Hospital, Kansas City, Missouri
Sarah Suppes
Affiliation:
Department of Pharmacy, Children’s Mercy Hospital, Kansas City, Missouri
Tracy Sandritter
Affiliation:
Department of Pharmacy, Children’s Mercy Hospital, Kansas City, Missouri
Jason G. Newland
Affiliation:
Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri
Lory Harte
Affiliation:
Department of Pharmacy, Children’s Mercy Hospital, Kansas City, Missouri
Jennifer L. Goldman*
Affiliation:
Department of Pediatrics, Children’s Mercy Hospital, Kansas City, Missouri
*
Authors for correspondence: David F. Butler, MD, Division of Pediatric Critical Care Medicine, Department of Pediatrics, Seattle Children’s Hospital, University of Washington School of Medicine, FA.2.112, 4800 Sand Point Way NE, Seattle WA 98105. E-mail: david.butler@seattlechildrens.org. Also, Jennifer Goldman MD, MS Divisions of Pediatric Infectious Diseases & Clinical Pharmacology, Department of Pediatrics, Children’s Mercy Hospital, 2401 Gillham Rd, Kansas City, MO 64108. E-mail: jlgoldman@cmh.edu
Authors for correspondence: David F. Butler, MD, Division of Pediatric Critical Care Medicine, Department of Pediatrics, Seattle Children’s Hospital, University of Washington School of Medicine, FA.2.112, 4800 Sand Point Way NE, Seattle WA 98105. E-mail: david.butler@seattlechildrens.org. Also, Jennifer Goldman MD, MS Divisions of Pediatric Infectious Diseases & Clinical Pharmacology, Department of Pediatrics, Children’s Mercy Hospital, 2401 Gillham Rd, Kansas City, MO 64108. E-mail: jlgoldman@cmh.edu
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Abstract

We retrospectively evaluated the effect of penicillin adverse drug reaction (ADR) labeling on surgical antibiotic prophylaxis. Cefazolin was administered in 86% of penicillin ADR-negative (−) and 28% penicillin ADR-positive (+) cases. Broad-spectrum antibiotic use was more common in ADR(+) cases and was more commonly associated with perioperative adverse drug events.

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , Volume 39 , Issue 12 , December 2018 , pp. 1480 - 1483
Copyright
© 2018 by The Society for Healthcare Epidemiology of America. All rights reserved. 

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Footnotes

†

Present affiliation: Division of Pediatric Critical Care, University of Washington, Seattle Children’s Hospital, Seattle, Washington.

Cite this article: Butler DF et al. (2018). Variability of surgical prophylaxis in penicillin-allergic children. Infection Control & Hospital Epidemiology 2018, 39, 1480–1483. doi: 10.1017/ice.2018.244

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