Hostname: page-component-78c5997874-dh8gc Total loading time: 0 Render date: 2024-11-16T07:59:42.586Z Has data issue: false hasContentIssue false

An Appraisal of Liver Transplantation in Great Britain

Published online by Cambridge University Press:  10 March 2009

John G. O'Grady
Affiliation:
King's College School of Medicine and Dentistry
Roger Williams
Affiliation:
King's College School of Medicine and Dentistry

Extract

Since the National Institutes of Health (NIH) Consensus Development Conference (1983) concluded that liver transplantation was a procedure deserving of wider application to the treatment of end-stage liver disease, there has been a very considerable increase in the number of centers performing liver transplantation, in Europe as well as in the United States. The number of operations performed has increased logarithmically (Figure 1, in Höckerstedt and Kankaanpää, p. 453). With the detailed overall assessment of liver transplantation in Europe by Höckerstedt and Kankaanpää, we will take the opportunity to review the position in Great Britain from a physician's, i.e., non-surgeon's, viewpoint as seen from one of the two centers (Cambridge/King's College and Birmingham) currently recognized in this country. This is based on an experience of 255 cases dating from the first liver transplant performed in Great Britain by Professor Roy Y. Calne in May 1968.

Type
Special Section: Transplantation and Artificial Organs
Copyright
Copyright © Cambridge University Press 1986

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

1.Neuberger, J. M., Altman, D. G., Christensen, E., Tygstrup, N., & Williams, R. Use of a prognostic index in liver transplantation for primary biliary cirrhosis. Transplantation, (In Press).Google Scholar
2.Shaw, B. W., Gordon, R. D., Iwatsuki, S., & Starzl, T. E.Retransplantation of the liver. Seminars in Liver Disease, 1985, 5, 394401.CrossRefGoogle ScholarPubMed
3.Watts, R. W. E., Calne, R. Y., Williams, R., Marshall, M. A., Veall, N., Purkiss, P., & Rolles, K.Primary hyperoxaluria (Type 1): Attempted treatment by combined hepatic and renal transplantation. Quarterly Journal of Medicine, 1985, 222, 697703.Google Scholar
4.O'Grady, J. G., Fagan, E. A., & Williams, R. Fulminant viral hepatitis. Clinics in Tropical Medicine and Communicable Diseases, (In Press).Google Scholar
5.Iwatsuki, S., Gordon, R. D., Shaw, B. W., & Starzl, T. E.Role of liver transplantation in cancer therapy. Annals of Surgery, 1985, 202, 401407.CrossRefGoogle ScholarPubMed
6.Shaw, B. W., Starzl, T. E., Iwatsuki, S., Gordon, R. D., & Esquivel, C., Liver transplantation in adults with hepatitis, Hepatology, 1985, 5, A462.Google Scholar
7.Shaw, B. W., Wood, R. P., Gordon, R. D., Iwatsuki, S., Gillguist, W. P., & Starzl, T. E.Influence of selected patient variables and operative blood loss on six-month survival following liver transplantation. Seminars in Liver Disease, 1985, 5, 385393.CrossRefGoogle ScholarPubMed
8.Memsic, L. D. F.Survival after liver transplantation. In R. W. Busuttil, Moderator, Liver transplantation today. Annals of Internal Medicine, 1986, 104, 377389.Google Scholar
9.Mowat, A. P. Personal communication, 1986.Google Scholar