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BENEFITS OF CONTINUOUS SUBCUTANEOUS INSULIN INFUSION ON QUALITY OF LIFE

Published online by Cambridge University Press:  28 December 2012

Andrea Lukács ,
Emőke Kiss-Tóth ,
Beatrix Varga ,
Andrea Soós ,
Peter Takác  and
László Barkai
Andrea Lukács
Affiliation:
Faculty of Health Care, University of Miskolc
Emőke Kiss-Tóth
Affiliation:
Faculty of Health Care, University of Miskolc
Beatrix Varga
Affiliation:
Faculty of Economics, University of Miskolc
Andrea Soós
Affiliation:
Department of Pediatrics, Borsod County University Hospital, Miskolc
Peter Takác
Affiliation:
Faculty of Health Care, University of Miskolc
László Barkai
Affiliation:
Faculty of Health Care, University of Miskolc; Postgraduate Institute of Pediatrics, Medical and Health Science Center, University of Debrecen
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Abstract

Purpose: The aim of this study was to compare the general health-related quality of life (HRQoL), the metabolic control (HbA1c), the anthropometric measurement, and the cardiorespiratory fitness (expressed by VO2max) in youths with type 1 diabetes treated with continuous subcutaneous insulin infusion (CSII) to those receiving multiple daily injections (MDI). We looked for factors influencing the HRQoL and metabolic control.

Methods: A total of 239 patients treated with CSII (51 girls and 53 boys) or MDI (64 girls and 71 boys) between ages 8 and 18 years were assessed with the Pediatric Quality of Life Inventory, Generic Core Scales, and Diabetes Module. VO2max was evaluated using the 20-meter shuttle run test.

Results: CSII group had significantly better HRQoL according to both child self-report and parent proxy-report. Youths with CSII reported better physical, emotional, and school-related functioning, and had less diabetes-related fear and symptoms than the MDI group. There were no significant differences in body mass index z-scores, insulin doses, HbA1c, and VO2max between the groups. HRQoL was predicted by the CSII therapy (β = −0.220; p = .000) and the VO2max (β = 0.386; p = .000), other clinical and anthropometric parameters had no effect; the HbA1c was predicted only by VO2max (β = −0.353; p = .000).

Conclusions: Diabetic youths treated with CSII therapy have better HRQoL than those treated with MDI. There are no differences between the investigated groups in anthropometric data, glycated hemoglobin, and physical fitness. Moreover, good physical fitness has an important role in achieving better metabolic control and HRQoL, which underlines the importance of regular aerobic exercise in the treatment and care of type 1 diabetes in childhood.

Keywords

Type 1 diabetes mellitusChildrenAdolescentsHealth-related quality of lifeContinuous subcutaneous insulin infusion
Type
ASSESSMENTS
Information
International Journal of Technology Assessment in Health Care , Volume 29 , Issue 1 , January 2013 , pp. 48 - 52
Copyright
Copyright © Cambridge University Press 2013

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