Hostname: page-component-78c5997874-dh8gc Total loading time: 0 Render date: 2024-11-15T07:05:02.014Z Has data issue: false hasContentIssue false
  • English
  • Français

Economic Analysis Alongside Clinical Trials: Bias in the Assessment of Economic Outcomes

Published online by Cambridge University Press:  10 March 2009

Leon B. Ellwein  and
Michael F. Drummond
Leon B. Ellwein
Affiliation:
National Eye Institute
Michael F. Drummond
Affiliation:
University of York
Get access Rights & Permissions [Opens in a new window]

Abstract

Clnical trial randomization schemes to control patient characteristics that can influence clinical response are not sufficient to control for their effects on operational efficiency and cost within the provider institution. This variation can result in biased economic findings when patients are allowed to select a provider themselves.

Type
General Essays
Information
International Journal of Technology Assessment in Health Care , Volume 12 , Issue 4 , Fall 1996 , pp. 691 - 697
Copyright
Copyright © Cambridge University Press 1996

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

1.Adams, M. E., McCall, N. T., Gray, D. T., et al. Economic analysis in randomized control trials. Medical Care, 1992, 30, 231–43.CrossRefGoogle ScholarPubMed
2.Briggs, A., Sculpher, M., & Buxton, M.Uncertainty in the economic evaluation of health care technologies: The role of sensitivity analysis. Health Economics, 1994, 3, 95–104.CrossRefGoogle ScholarPubMed
3.Cooper, R., & Kaplan, R. S.Measure costs right: Make the right decisions. Harvard Business Review, 1988, 66, 96–103.Google Scholar
4.Drummond, M. F., & Davies, L.Economic analysis alongside clinical trials: Revisiting the methodological issues. International Journal of Technological Assessment of Health Care, 1991, 7, 561–73.CrossRefGoogle ScholarPubMed
5.Drummond, M. F., & Stoddart, G. L.Economic analysis and clinical trials. Controlled Clinical Trials, 1984, 5, 115–28.CrossRefGoogle ScholarPubMed
6.Freund, D. A., Evans, D., Henry, D., et al. Implications of the Australian guidelines for the United States. Health Affairs, 1992, 11, 202–06.CrossRefGoogle ScholarPubMed
7.Friedman, L. M., Furberg, C. D., & DeMets, D. L.Fundamentals of clinical trials, 2nd ed.Littleton, MA: PSG Publishing Company, Inc., 1985.Google Scholar
8.Kaplan, R. S.Management accounting for advanced technological environments. Science 1989, 245, 819–23.CrossRefGoogle ScholarPubMed
9.Pare, T. P. A new tool for managing costs. Fortune, 06 14, 1993, 124–29.Google Scholar