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Volume and Outcome of Organ Transplantation

Published online by Cambridge University Press:  14 October 2009

H. David Banta ,
Gerard L. Engel  and
Tore Scherstén
H. David Banta
Affiliation:
Netherlands Organization for Applied Scientific Research (TNO)
Gerard L. Engel
Affiliation:
Maastricht University Hospital
Tore Scherstén
Affiliation:
Sahlgrenska Hospital, Goteborg
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Abstract

In general, technically demanding medical procedures are associated with better outcomes when they are carried out in institutions and by physicians with higher volumes of practice. This paper examines the evidence for a volume–outcome relationship in the case of organ transplantation. Although few studies have been done on this subject, existing evidence is consistent with improved outcomes at higher volumes. Therefore, evidence supports policies that regionalize transplantation services.

Type
General Essays
Information
International Journal of Technology Assessment in Health Care , Volume 8 , Issue 3 , Summer 1992 , pp. 490 - 505
Copyright
Copyright © Cambridge University Press 1992

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References

REFERENCES

1.Adams, D. F., Fraser, D. B., & Abrams, H. L.The complications of coronary arteriography. Circulation, 1973, 48, 609–18.CrossRefGoogle ScholarPubMed
2.Annas, G. J.Regulating heart and liver transplants in Massachusetts: An overview of the Report of the Task Force on Organ Transplantation. Law, Medicine & Health Care, 1985, 13, 4–7.Google ScholarPubMed
3.Anthony, C. R.Federal financing of transplantation. Transplantation Proceedings, 1988, 20(suppl.), 1047–50.Google ScholarPubMed
4.Balk, A. H. M. M., Simoons, M. L., Mochtar, B., & Weimar, W.Heart transplantation, a sensible alternative, results of the Heart Transplantation Working Group Rot-terdam/Leiden/Nieuwegein. Netherlands Journal of Cardiology. 1988, 1, 35–40.Google Scholar
5.Benlahrache, C., Cecka, M., Mickey, M. R., & Cicciarelli, J. The center effect. In Terasaki, P. (ed.), Clinical transplants. Los Angeles, CA: UCLA Tissue Typing Laboratory, 1987, 325–37.Google Scholar
6.Blue Cross and Blue Shield Association, Technology Evaluation & Coverage, Health Benefits Management Division. Criteria for evaluating institutions for liver & heart transplants. Chicago, IL: Blue Cross/Blue Shield, 1985.Google Scholar
7.de Charro, F., & Banta, H. D.Transplant policy in the Netherlands. International Journal of Technology Assessment in Health Care, 1986, 2, 533–44.CrossRefGoogle ScholarPubMed
8.Cook, D. J. Long-term survival of kidney allografts. In Terasaki, P. (ed.), Clinical transplants. Los Angeles, CA: UCLA Tissue Typing Laboratory, 1987, 277–85.Google Scholar
9.de Lissovoy, G.Medicare and heart transplants: Will lightning strike twice? Health Affairs, 1988, 8, 61–72.CrossRefGoogle Scholar
10.Eurotransplant Foundation. Annual report 1987. Leiden, the Netherlands.Google Scholar
11.Eurotransplant Foundation. Eurotransplant Newsletter. Leiden, the Netherlands: February 1989.Google Scholar
12.Evans, R. W.Health care technology and the inevitability of resource allocation and rationing decisions, Part II. Journal of the American Medical Association, 1983, 249, 2208–19.CrossRefGoogle ScholarPubMed
13.Evans, R. W., Manninen, D. L., Garrison, L. P., et al. The quality of life of patients with end-stage renal disease. New England Journal of Medicine, 1985, 312, 553–59.CrossRefGoogle ScholarPubMed
14.Evans, R. W., Manninen, D. L., Overcase, T. D., et al. National heart transplantation study. Seattle, WA: Battelle Human Affairs Research Centers, 1984.Google Scholar
15.Farber, B. F., Kaiser, D. L., & Wenzel, R. P.Relation between surgical volume and incidence of postoperative wound infection. New England Journal of Medicine, 1981, 305, 200–04.CrossRefGoogle ScholarPubMed
16.Flatmark, A.Foreword. Transplantation Proceedings, 1988, 20, 361.Google Scholar
17.Flood, A. B., Scott, W. R., & Ewy, W.Does practice make perfect? Part I: The relation between hospital volume and outcomes for selected diagnostic categories. Medical Care, 1984, 22, 98–114.CrossRefGoogle ScholarPubMed
18.Foster, W. R., & Burton, B. T.Technology assessment applied to liver transplantation in adults. International Journal of Technology Assessment in Health Care, 1989, 5, 173–82.CrossRefGoogle ScholarPubMed
19.Fowles, J., Bunker, J. P., Oda, M., et al. Surgery data yield quality indicators. Business and Health, 1987, 4, 44–46.Google ScholarPubMed
20.Fox, R. C., & Swazey, J. P.The courage to fail. Chicago, IL: The University of Chicago Press, 1974, 1978.Google Scholar
21.Friedlander, G. E.Tissue transplantation: Allocation and related issues. Transplantation Proceedings, 1988, 20(suppl.), 1017–21.Google Scholar
22.Gezondheidsraad. Harttransplantatie. The Hague: January 27, 1989 (summary in English).Google Scholar
23.Gezondheidsraad. Levertransplantatie. The Hague: March 16, 1989 (summary in English).Google Scholar
24.Gezondheidsraad. Algemene Transplantatieproblematiek. The Hague: January 30, 1987 (translated to English: Transplantation).Google Scholar
25.Gilks, W., Bradley, B. A., Gore, S. M., & Selwood, N. H.Immunogenic and clinical factors affecting renal transplantation. Transplantation, 1986, 42, 39–45.CrossRefGoogle ScholarPubMed
26.Gilks, W., Gore, S. M., & Bradley, B. A.Analyzing transplant survival data. Transplantation, 1986, 42, 46–49.CrossRefGoogle ScholarPubMed
27.Groot, L. M. J. Study on regulatory mechanisms of the diffusion of expensive health technology in the member states of the EC. Report to the European Commission, Brussels, August 1986.Google Scholar
28.Hannan, E. L., O'Donnell, J. F., Kilburn, H., et al. Investigation of the relationship between volume and mortality for surgical procedures performed in New York state hospitals. Journal of the American Medical Association, 1989, 262, 503–10.CrossRefGoogle ScholarPubMed
29.Hartz, A. J., Krakauer, H., Kuhn, E. M., et al. Hospital characteristics and mortality rates. New England Journal of Medicine, 1989, 321, 1720–25.CrossRefGoogle ScholarPubMed
30.Hertzler, N. R., Avellone, J. C., Farrell, C. J., et al. The risk of vascular surgery in a metropolitan community. Journal of Vascular Surgery, 1984, 1, 13–21.CrossRefGoogle Scholar
31.Hockerstedt, K., & Kankaanpaa, J.Liver transplantation in Europe-Present status. International Journal of Technology Assessment in Health Care, 1986, 2, 451–63.CrossRefGoogle ScholarPubMed
32.Hughes, R. G., Garnick, D. W., Luft, H. S., et al. Hospital volume and patient outcomes: The case of hip fracture patients. Medical Care, November, 1988.CrossRefGoogle ScholarPubMed
33.Hughes, R. G., Hunt, S. S., & Luft, H. S.Effects of surgeon volume and hospital volume on quality of care in hospitals. Medical Care, 1987, 25, 489–503.CrossRefGoogle ScholarPubMed
34.Human Renal Transplant Registry. Eleventh report. Journal of the American Medical Association, 1973, 226, 1197–204.Google Scholar
35.Johnson, J. O., McGauly, C. T., & Copley, J. B.The quality of life of hemodialysis or transplant patients. International Volume, 1982, 22, 286–91.Google ScholarPubMed
36.Kaye, M. P. The Registry of the International Society for Heart Transplantation: Fourth official report–1987. In Terasaki, P. (ed.), Clinical transplants. Los Angeles, CA: UCLA Tissue Typing Laboratory, 1987, 1–6.Google Scholar
37.Kaye, M. P., Elcombe, S. A., & O'Fallon, W. M.The International Heart Transplantation Register: The 1984 report. Heart Transplantation, 1985, 4, 290–92.Google Scholar
38.Kelly, J. V. Deaths in teaching and nonteaching hospitals: Quality of care and severity of illness differences (forthcoming).Google Scholar
39.Kelly, J. V., & Hellinger, F. K. J.Physician and hospital factors associated with mortality of surgical patients. Medical Care, 1986, 24, 785–800.CrossRefGoogle ScholarPubMed
40.Kelly, J. V., & Hellinger, F. J.Heart disease and hospital deaths: An empirical study. Health Services Research, 22, 369–95.Google Scholar
41.Kempczinski, R. F., Brott, T. G., & Labutta, R. J.The influence of surgical specialty and caseload on the results of carotid endarterectomy. Journal of Vascular Surgery, 1986, 3, 911–16.CrossRefGoogle ScholarPubMed
42.Kirkpatrick, C. H.Transplantation immunology. Journal of the American Medical Association, 1987, 258, 2993–3000.CrossRefGoogle ScholarPubMed
43.Luft, H. S.The relation between surgical volume and mortality: An exploration of causal factors and alternative models. Medical Care, 1980, 18, 940–59.CrossRefGoogle ScholarPubMed
44.Luft, H. S., Bunker, J. P., & Anthoven, A. C.Should operations be recognized? New England Journal of Medicine, 1979, 301, 1364–69.CrossRefGoogle Scholar
45.Luft, H. S., & Hunt, S. S.Evaluating individual hospital quality through outcome statistics. Journal of the American Medical Association, 1986, 255, 2780–84.CrossRefGoogle ScholarPubMed
46.Luft, H. S., Hunt, S. S., & Maerki, S. C.The volume-outcome relationship: Practice makes perfect or selective referral patterns? Health Services Research, 1987, 22, 157–82.Google ScholarPubMed
47.Lutz, S.Organ transplant programs multiply. Modern Health Care, March 4, 1988, 23–31.Google ScholarPubMed
48.Maerki, S. C., Luft, H. S., & Hunt, S. S.Selecting categories of patients for regionalization: Implications of the relationship between volume and outcome. Medical Care, 1986, 24, 148–58.CrossRefGoogle ScholarPubMed
49.Morris, P. J.Are there ethical problems posed by multiple small transplant centres? Transplant International, 1988, 1, 47–48.CrossRefGoogle ScholarPubMed
50.National Institutes of Health. Liver transplantation. Consensus development conference summary, vol. 4, no. 7. Bethesda, MD.Google Scholar
51.Office of Technology Assessment. The quality of medical care, information for consumers. Washington, DC: U.S. Government Printing Office, 1988.Google Scholar
52.Opelz, G., Mickey, M. R., & Terasaki, P. I.Calculations on long-term graft and patient survival in human kidney transplantation. Transplantation Proceedings, 1977, 9, 27–30.Google ScholarPubMed
53.Opelz, G., Mickey, M. R., & Terasaki, P. I.Comparison of kidney transplant survival among transplant centers. Transplantation, 1975, 19, 226–29.CrossRefGoogle ScholarPubMed
54.Opelz, G., & Terasaki, P. I.International study of histocompatibility in renal transplantation. Transplantation, 1982, 33, 87–95.CrossRefGoogle Scholar
55.Persijn, G. Personal communication, March 22, 1989.Google Scholar
56.Pilcher, D. B., Davis, J. H., Ashikaga, T., et al. Treatment of abdominal aortic aneurysm in an entire state over 7½ years. American Journal of Surgery, 1980, 139, 487–94.CrossRefGoogle Scholar
57.Riley, G., & Lubitz, J.Outcome of surgery among the Medicare aged: Surgical volume and mortality. Health Care Financing Review, 1985, 7, 37–47.Google ScholarPubMed
58.van Rood, J. J. A proposal for international cooperation in organ transplantation: Eu-rotransplant. In Curtoni, E. S., Mattiuz, P. L., & Tosi, R. N. (eds.), Histocompatibility testing. Copenhagen: Munksgaard, 1967, 451–56.Google Scholar
59. van Rood, J. J., Persijn, G. G., Cohen, B., et al. Hierarchy of factors influencing kidney graft survival. Dialysis and Transplant, 1982, 11, 111–18.Google Scholar
60.Roos, L. L., Cageorge, S. M., Roos, N. P., et al. Centralization, certification, and monitoring readmissions and complications after surgery, Medical Care, 1986, 24, 1044–66.CrossRefGoogle ScholarPubMed
61.Roos, L. L., Roos, N. P., & Sharp, S. M.Monitoring adverse outcomes of surgery using administrative data. Health Care Financing Review, December 1987(suppl.), 5–16.Google ScholarPubMed
62.Rosenblatt, R. A., Reinken, J., & Shoemack, P.Is obstetrics safe in small hospitals? Evidence from New Zealand's regionalised perinatal system. Lancet, 1985, ii, 429–32.CrossRefGoogle Scholar
63.Shortell, S. M., & LoGerfo, J. P.Hospital medical staff organization and quality of care: Results for myocardial infarction and appendectomy. Medical Care, 1981, 19, 1041–53.CrossRefGoogle ScholarPubMed
64.Showstack, J. A., Rosenfeld, K. E., Garnick, D. W., et al. Association of volume with outcome of coronary artery bypass graft surgery. Journal of the American Medical Association, 1987, 257, 785–89.CrossRefGoogle ScholarPubMed
65.Simmons, R. G., et al. Quality of life and alternate ESRD therapies. International Reports of the Union of Minnesota, 1981, 10–14.Google Scholar
66.Sloan, F. A., Perrin, J. M., & Valvona, F.In-hospital mortality of surgical patients: Is there an empiric basic for standard setting? Surgery, 1986, 99, 446–53.Google Scholar
67.Starzl, T. E., Iwatsuki, S., Shaw, B. W., et al. Analysis of liver transplant. Hepatology, 1984, 4, 475–95.CrossRefGoogle Scholar
68.Starzl, T. E., Iwatsuki, S., van Thiel, D., et al. Evolution of liver transplantation. Hepatology, 1982, 2, 614–36.CrossRefGoogle ScholarPubMed
69.Sutherland, D. E. R., & Kendall, D.Clinical pancreas and islet transplant registry report. Transplantation Proceedings, 1985, 18, 307–11.Google Scholar
70.Sutherland, D. E. R., & Moudry, K. C. Report of the International Pancreas Transplant Registry. In Terasaki, P. (ed.), Clinical transplant. Los Angeles, CA: UCLA Tissue Typing Laboratory, 1987, 63–101.Google Scholar
71.Taylor, R. M. R., Ting, A., & Briggs, J. D.Renal transplantation in the United Kingdom and Ireland-The Centre Effect. Lancet, 1985, i, 798–805.CrossRefGoogle Scholar
72.Terasaki, P. I., Mickey, M. R., Cecka, M., et al. Overview. In Terasaki, P. (ed.), Clinical transplants. Los Angeles, CA: UCLA Tissue Typing Laboratory, 1987, 467–90.Google Scholar
73.Thorogood, J., van Houwelingen, J. C., van Rood, J. J., & Persijn, G. G.The impact of centre variation on the HLA-DR matching effect in kidney graft survival. Transplantation, 1989, 48, 231–38.CrossRefGoogle ScholarPubMed
74.U.S. Department of Health and Human Services. Scientific and clinical status of organ transplantation: Report for 1987. Washington, DC: U.S. Public Health Service, 1987.Google Scholar
75.Welch, H. G., & Larson, E. B.Dealing with limited resources, the Oregon decision to curtail funding for organ transplantation. New England Journal of Medicine, 1988, 319, 171–73.CrossRefGoogle ScholarPubMed
76.Wennberg, J. E., Roos, N., Sola, L., et al. Use of claims data systems to evaluate health care outcomes: Mortality and reoperation following prostatectomy. Journal of the American Medical Association, 1987, 257, 933–36.CrossRefGoogle ScholarPubMed
77.Williams, R. L.Measuring the effectiveness of perinatal medical care. Medical Care, 1979, 17, 95–109.CrossRefGoogle ScholarPubMed