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The Chemistry and Anticonvulsant Action of Paltothyreus tarsatus Extracts

Published online by Cambridge University Press:  19 September 2011

S. K. Adesina
Affiliation:
Drug Research and Production Unit, Faculty of Pharmacy, University of Ife, Ile-Ife, Nigeria
S. O. Awe
Affiliation:
Drug Research and Production Unit, Faculty of Pharmacy, University of Ife, Ile-Ife, Nigeria
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Abstract

Paltothyreus tarsatus F. extracts showed anticonvulsant effects in laboratory mice. Chemical examination of Paltothyreus tarsatus revealed the presence of alkyl sulphides (8.5%), ketones (9%), fatty acids (50%), small amounts of alkanes, alkenes and sterol. Constituents were analysed by gas chromatography. Tentative identification of the unknown was confirmed by comparison of its mass spectrometry and its gas chromatography retention time with those of an authentic sample and by co-injection.

Résumé

Les extraits de Paltothyreus tarsatus F. ont montré des effects anticonvulsivants chez des souris de laboratoire. Un examen chimique du P. tarsatus a révélé la presence d'alkyl sulfures (8.5%), de cetones (9%), d'acides gras (50%), de petites quantites d'alkanes, d'alkenes et de sterol. Les éléments constitutifs etaient analysés par la chromatographie à gaz. Une identification provisoire de l'inconnu été confirmé par la comparaison la spectrometrie de la masse et la durée de rétention et chromatographie à gaz avec celles d'un spécimen authentique et aussi parmoyen de co-injection.

Type
Research Articles
Copyright
Copyright © ICIPE 1988

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References

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