Hostname: page-component-78c5997874-mlc7c Total loading time: 0 Render date: 2024-11-10T11:11:37.719Z Has data issue: false hasContentIssue false

Ecological and physiological factors in the cyclic transmission of african trypanosomiasis

Published online by Cambridge University Press:  19 September 2011

F. L. Lambrecht
Affiliation:
International Centre of Insect Physiology and Ecology, P.O. Box 30772, Nairobi, Kenya
Get access

Abstract

The cyclic transmission of African trypanosomes is subject to the successful passage through successive ‘biological barriers’ associated with the ecology and physiology of the host(s) and vector(s), and the ability of the parasite to adjust to the various substrates. This paper is an analytical compilation of factors which play a relevant role in the complex pathway characteristic of trypanosome transmission. These are discussed under the following headings: (a) physiology of the parasite; (b) physiology of the vector; (c) ecology of the vector; (d) feeding habits of the vector; (e) physiology of the vertebrate host; and (f) behaviour of the vertebrate host.

Type
Research Article
Copyright
Copyright © ICIPE 1980

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Allsop, R., Baldry, D. A. T. and Rodrigues, C. (1972) The influence of game animals on the distribution and feeding habits of Glossina pallidipes in the Lambwe Valley. Bull. Wld. Hlth. Org. 47, 795809.Google Scholar
Amreim, Y. U., Geighy, R. and Kaufmann, M. (1965) On the reacquisition of virulence in trypanosomes of the brucei group. Acta trop. 22, 193203.Google Scholar
Ashcroft, M. T. (1959) The importance of African wild animals as reservoirs of trypanosomiasis. E. Afri. Med. J. 36, 247–161.Google ScholarPubMed
Ashcroft, M. T., Burt, E. and Fairbairn, H. (1959) The experimental infection of some African wild animals with T. rhodesiense, T. brucei and T. congolense. Ann. trop. Med. Parasit. 53, 137146.CrossRefGoogle Scholar
Baker, J. R. (1968) Trypanosomes of wild animals in the neighbourhood of the Serengeti National Park. Symp. Zool. Soc. Lond. 24, 147158.Google Scholar
Baker, J. R., Sachs, R. and Laufer, I. (1967) Trypanosomes of wild animals in an area northwest of the Serengeti National Park. Z. Tropenmed. Parasit. 18, 280284.Google Scholar
Burtt, E. (1946) Incubation of tsetse pupae: increased transmission rate of Trypanosoma rhodesiense in Glossina morsitans. Ann. trop. Med. Parasit. 40, 1828.CrossRefGoogle ScholarPubMed
Buxton, P. A. (1955) The Natural History of Tsetse Flies. Mem. London Sch. Hyg. & Trop. Med., No. 10.Google Scholar
Challier, A., Eyraud, M., Lafaye, A. and Laveissiere (1977) Amélioration du rendement de piège biconique pour Glossines par l'emploi d'un cône inférieur bleu. Cah. O.R.S.T.O.M., sér. ent. med. parasit. XV, 282286.Google Scholar
Clarke, J. E. (1965) Trypanosomes infections in the mouthparts of Glossina morsitans: a correlation between the extent of labral infection and invasion of the hypopharynx. Ann. trop. Med. Parasit. 59, 235239.CrossRefGoogle ScholarPubMed
Clarke, J. E. (1966) Trypanosome infections in the mouthpart of Glossina morsitans: variation in frequency and extent of labral infections with age. Ann. trop. Med. Parasit. 60, 223229.CrossRefGoogle ScholarPubMed
Clarke, J. E. (1970) Trypanosome infection rates in the mouthparts of Zambián tsetse flies. Ann. trop. Med. Parasit. 64, 164165.Google Scholar
Cunningham, M. P. and Vickerman, K. (1962) Antigenic analyses of the Trypanosome brucei group, using the agglutination reaction. Trans. R. Soc. trop. Med. Hyg. 56, 4859.CrossRefGoogle Scholar
Damian, R. T. (1964) Molecular mimicry: antigen sharing by parasite and host and its consequences. Am. Naturalist 98, 129149.CrossRefGoogle Scholar
De Andrea Silva, M. A. and Marques Da Silva, J. (1958) On the incidence of Trypanosomiasis in game. C.S.I.T.R., 1th Meeting, 269–212.Google Scholar
Desowitz, R. and Watson, H. J. C. (1953) Studies on Trypanosoma vivax. IV. The maintenance of a strain in white rats without sheepserum supplement. Ann. trop. Med. Parasit. 47, 6267.CrossRefGoogle ScholarPubMed
Dodin, A. and Fromentin, H. (1962) Mise en évidence d'un antigène vaccinant dans le plasme de souris expérimentalement infectées par Trypanosoma gambiense et par T. congolense. Bull. Soc. Path. exot. 55, 128138.Google Scholar
Erickson, I. C. and Moller, A. R. (1975) Tsetse fly Glossina morsitans morsitans produces ultrasound related to behaviour. Experimentia 31, 788790.CrossRefGoogle Scholar
Fairbairn, H. and Burtt, E. (1946) The infectivity to man of a strain of Trypanosoma rhodesience transmitted cyclically by Glossina morsitans through sheep and antelope: evidence that man requires a minimum infective dose of metacyclic trypanosomes. Ann. trop. Med. Parasit. 40, 270313.CrossRefGoogle Scholar
Fairbairn, H. and Culwick, A. T. (1950) The transmission of polymorphic trypanosomes. Acta trop. 7, 1947.Google Scholar
Ford, J. and Leggate, B. M. (1961) The geographical and climatic distribution of trypanosome infection rates in Glossina morsitans group of flies. Trans. R. Soc. trop. Med. Hyg. 55, 383397.CrossRefGoogle Scholar
Frezil, J. L. (1971) Application du xénodiagnostic dans le dépistage de la trypanosomiase a T. gambiense chez des sujets immunologiquement suspect. Bull. Soc. Path. Exot. 64, 871878.Google Scholar
Frezil, J. L. and Carnevale, P. (1976) Utilisation de la carboglace pour la capture de Glossina fuscipes quanzensis avec le piège Challier-Laveissière. Conséquences épidémiologiques. Cah. O.R.S.T.O.M., ser. Ent. méd. parasit. XIV, 225233.Google Scholar
Galun, R. (1975) The role of host-blood in the feeding behaviour of ectoparasites. In Dynamic Aspects of Host-Parasite Relationship, Vol. II (Ed. by Zuckerman, A.), John Wiley, New York.Google Scholar
Geigy, R., Kauffmann, M. and Beglinger, R. (1967) A survey of wild animals as potential reservoirs of trypanosomiasis in the U langa District (Tanzania). Acta trop. 24, 97108.Google Scholar
Geigy, R. and Kauffmann, M. (1973) Sleeping sickness survey in the Serengeti area (Tanzania) 1971. I. Examination of large mammals for trypanosomes. Acta. trop. 30, 1223.Google ScholarPubMed
Geigy, R. M., Kauffmann, M., Mayende, J. S. P., Mwambu, P. M. and Onyango, R. J. (1973) Isolation of Trypanosoma rhodesiense from game and domestic animals in Musoma District, Tanzania. Acta. trop. 30, 4956.Google ScholarPubMed
Glasgow, J. P. (1961) The feeding habits of Glossina swynnertoni. J. Anim. Ecol. 30, 7785.CrossRefGoogle Scholar
Glasgow, J. P. and Wilson, F. (1953) A census of the tsetse fly Glossina pallidipes Austen and of its host animals. J. Anim. Ecol. 22, 4756.CrossRefGoogle Scholar
Glasgow, J. P., Isherwood, F., Lee-Jones, F. and Weitz, B. (1958) Factors influencing the staple food of tsetse. J. Ann. Ecol. 27, 5969.CrossRefGoogle Scholar
Godfrey, D. G. (1961) Types of Trypanosoma congolense. II. Differences in the course of infection. Ann. trop. Med. Parasit. 55, 154.CrossRefGoogle Scholar
Gray, A. R. (1965) Antigenic variations in a strain of Trypanosoma brucei transmitted by Glossina morsitans and G. palpalis. J. gen. Microbiol. 41, 195214.CrossRefGoogle Scholar
Gray, A. R. (1975) A pattern in the development of agglutino-genic antigens of cyclically transmitted isolates of Trypanosoma gambiense. Trans. R. Soc. trop. Med. Hyg. 69, 131138.CrossRefGoogle ScholarPubMed
Harley, J. M. B. (1971) Comparison of the susceptibility to infection with Trypanosoma rhodesiense of Glossina pallidipes, G. fuscipes and G. brevipalpis. Ann. trop. Med. Parasit. 65, 191196.CrossRefGoogle ScholarPubMed
Harley, J. M. B., Cunningham, M. P. and Van Hoeve, K. (1966) The numbers of infective Trypanosoma rhodesiense extruded by Glossina morsitans during feeding. Ann. trop. Med. Parasit. 60, 455460.CrossRefGoogle Scholar
Harley, J. M. B. and Wilson, A. J. (1968) Comparison between Glossina morsitans, G. pallidipes and G. fuscipes as vectors of trypanosomes of the Trypanosoma congolense group; the proportions infected experimentally and the numbers of infective organisms extruded during feeding. Ann. trop. Med. Parasit. 62, 178187.CrossRefGoogle Scholar
Harmsen, R. (1973) The nature of the establishment barrier for Trypanosoma brucei in the gut of Glossina pallidipes. Trans. R. Soc. trop. Med. hyg. 67, 364373.CrossRefGoogle ScholarPubMed
Isherwood, F., Duffy, B. J., Glasgow, J. P., Lee-Jones, F. and Weitz, B. (1961) Further studies of the food of tsetse flies. J. Anim. Ecol. 30, 259266.CrossRefGoogle Scholar
Janssen, J. A. H. A. and Wijers, D. J. B. (1974) Trypanosoma simiae at the Kenya coast. A correlation between virulence and the transmitting species of Glossina. Ann. trop. Med. Parasit. 68, 519.CrossRefGoogle Scholar
Jordan, A. M. (1964) Trypanosome infection rate in Glossina morsitans submorsitans in northern Nigeria. Bull. ent. Res. 55, 219231.CrossRefGoogle Scholar
Jordan, A. M. (1965) The host of Glossina as the main factor affecting trypanosome infection rates of tsetse flies in Nigeria. Tvvrans. R. Soc. trop. Med. Hyg. 59, 423431.CrossRefGoogle Scholar
Kolbe, F. E. (1973) The modulated sounds made by the tsetse fly Glossina brevipalpis. Zoo. Afr. 8, 241258.Google Scholar
Lambrecht, F. L. (1964) Aspects of evolution and ecology of tsetse flies and trypanosomasis in prehistoric African environment. J. Afr. Hist. 5, 124.CrossRefGoogle Scholar
Lambrecht, F. L. (1965) Biological variations in trypanosomes and their relation to the epidemiology of Chagas' disease. Rev. Inst. Med. trop. Sao Paulo 7, 346352.Google Scholar
Lambrecht, F. L. (1967) Trypanosomiasis in prehistoric and later human populations: a tentative reconstruction. In Diseases in Antiquity (Ed. by Brothwell, and Sandson, ) Ch. C. Thomas, Illinois.Google Scholar
Lambrecht, F. L. (1973) Colour attraction of Glossina morsitans in N'gamiland, Botswana. J. trop. med. hyg. 76, 9496.Google ScholarPubMed
Lamprey, H. F., Glasgow, J. P., Lee-Jones, F. and Weitz, B. (1962) A simultaneous census of the potential and actual food sources of the tsetse fly Glossina swynnertoni, Austen. J. Anim. Ecol. 31, 151156.CrossRefGoogle Scholar
Langley, P. A. (1968) The effect of feeding the tsetse fly Glossina morsitans on impala blood. Bull. ent. Res. 58, 295298.CrossRefGoogle Scholar
Langley, P. A. (1976) Initiation and regulation of ingestion by haematophagous arthropods. J. med. ent. 13, 121130.CrossRefGoogle Scholar
Langridge, W. P. (1960) Scent attractants for tsetse flies. In Int. Sci. Comm. Tryp. Res., 8th Meeting.Google Scholar
Lehman, D. L. (1961) Attempts at the selective cultivation of Trypanosoma rhodesiense, T. brucei and T. congolense. Ann. Trop. Med. Parasit. 55, 440446.CrossRefGoogle Scholar
Lumsden, W. H. R. (1966) Estimation of serum Igm in the diagnosis of human trypanosomiasis. Trans. R. Soc. trop. Med. Hyg. 60, 125.CrossRefGoogle Scholar
Lumsden, W. H. R. (1967) Trends in research on the immunology of trypanosomiasis. Bull. Wid. Hlth. Org. 37, 167175.Google ScholarPubMed
Lumsden, W. H. R. and Evans, D. A. (1976) Biology of the Kinetoplastida. Academic Press, London.Google Scholar
Maillot, L. (1961) Répartition des Glossines et maladie du sommeil suivant les races géographiques. Bull. Soc. Path. Exot. 54, 856869.Google Scholar
Marks, A. D. (1966) Notes on the behaviour of tsetse flies (G. morsitans and G. pallidipes) with regard to impala. Interim report, Rhodesián Governm., Dept. Vet. Serv., Tsetse and Trypanosomiasis Control Branch.Google Scholar
Mschelbwala, A. S. (1972) Trypanosoma brucei infection in the haemocele of tsetse flies. Trans. R. Soc. trop. Med. Hyg. 66, 637643.CrossRefGoogle Scholar
Nash, T. A. M. (1948) A note on the effect of high temperature on the pupal stages of Glossina in relation to the transmission rate of Trypanosomes. Ann. trop. Med. Parasit. 42, 3032.CrossRefGoogle Scholar
Otieno, L. H. (1973) Trypanosoma brucei in the haemolymph of experimentally infected young Glossina morsitans. Trans. R. Soc. trop. Med. Hyg. 67, 886887.CrossRefGoogle ScholarPubMed
Prothero, R. M. (1963) Population mobility and trypanosomiasis in Africa. Bull. Wld. Hlth. Org. 28, 615623.Google ScholarPubMed
Rennisson, B. D. and Robertson, D. H. H. (1958) The use of carbon dioxide as an attractant for catching tsetse. E.A.T.R.O., Report 1958, p. 26.Google Scholar
Rice, M. J., Galun, R. and Margalit, J. (1973) Mouthpart sensilla of the tsetse fly and their function. III. Labrocibarial sensilla. Ann. trop. med. parasit. 67, 109116.CrossRefGoogle Scholar
Rifkin, M. R. (1978) Purification and identification of the trypanocidal factor from normal human serum. 4th Int. Congr. Parasit. Warsaw, 1978, section F, p. 42.Google Scholar
Rogers, A. (1969) The use of dry ice in trapping tsetse. E.A.T.R.O. Report, 1969, 8591.Google Scholar
Soltys, M. A. (1963) Immunity in African Trypanosomiasis. Bull. Wld. Hlth. Org. 28, 753761.Google ScholarPubMed
Soltys, M. A. and Woo, P. (1969) Multiplication of Trypanosoma brucei. Trans. R. Soc. trop. Med. Hyg. 63, 490496.CrossRefGoogle ScholarPubMed
Soltys, M. A., Woo, P. and Gillick, A. C. (1969) A preliminary note on the separate and infectivity of tissue forms of Trypanosoma brucei. Trans. R. Soc. trop. Med. Hyg. 63, 495496.CrossRefGoogle ScholarPubMed
Terry, R. J. (1976) Innate resistance to trypanosome infections. In Biology of the Kinetoplastida, (Ed. by Lumsden, and Evans, ), pp. 477492. Academic Press, London.Google Scholar
Turner, D. A. (1971) Olfactory perception of live host and carbon dioxide by the tsetse fly Glossina morsitans morsitans. Bull. ent. Res. 61, 7596.CrossRefGoogle Scholar
Turner, D. A. and Invest, J. F. (1973) Laboratory analyses of vision in tsetse flies (Dipt.: Glossinidae),. Bull. ent. Res. 62, 342357.CrossRefGoogle Scholar
Vale, G. A. (1966) Mobile attractants for tsetse flies. Arnoldia 4, No. 33.Google Scholar
Vale, G. A. (1974) New field methods for studying the responses of tsetse flies (Diptera: Glossinidae) to hosts. Bull. ent. Res. 64, 199208.CrossRefGoogle Scholar
Vale, G. A. and Hargrove, J. W. (1975) Field attraction of tsetse flies (Diptera: Glossinidae) to ox odour; the effect of dose. Trans. Rhodesian Sci. Assoc. 56, 4650.Google Scholar
Vanden Berghe, L. (1956) Aspect particular de la trypanosomiasis, maladie des pêcheurs, au Lac Tumba (Congo Belge.). Ann. Soc. Bel. Med. trop. 36, 185190.Google Scholar
Vanden Berghe, L. and Lambrecht, F. L. (1962) Etude bioloque et écologique dans la région du Bugesera (Ruanda). Acad. R. Sci. Outre-Mer, Mem. Tome XIII.Google Scholar
Vanden Berghe, L. and Lambrecht, F. L. (1963) The epidemiology and control of human trypanosomiasis in Glossina morsitans fly belts. Am. J. trop. Med. Hyg. 12, 129164.CrossRefGoogle Scholar
Vickerman, K. (1978) Antigenic variations in trypanosomes. Nature 273, 613617.CrossRefGoogle ScholarPubMed
Weinman, D. (1959) Cultivation of trypanosomes. Trans. R. Soc. trop. Med. Hyg. 51, 560561.CrossRefGoogle Scholar
Weitz, B. (1960) Feeding habits of bloodsucking arthropods. Exp. Parasit. 9, 6382.CrossRefGoogle Scholar
Weitz, B. (1963) The feeding habits of Glossina. Bull. Wld. Hlth. Org. 28, 711729.Google ScholarPubMed
Weitz, B. (1970) Host of Glossina. In The African Trypanosomiasis (Ed. by Mulligan, H. W.). Allen and Unwin, London.Google Scholar
Weitz, B. and Jackson, C. H. N. (1955) The host-animals of Glossina morsitans at Daga-Iloi. Bull. ent. Res. 46, 531538.CrossRefGoogle Scholar
Wijers, D. J. B. (1958) Factors that may influence the infection rate of Glossina palpalis with Trypanosoma gambiense. I. Age of the fly at the time of the infected feed. Ann. trop. Med. Parasit. 52, 385389.CrossRefGoogle ScholarPubMed
Wijers, D. J. B. and Willet, K. G. (1960) Factors that may influence the infection rate of Glossina palpalis with Trypanosoma gamhiense. II. The number and the morphology of the trypanosomes present in the blood of the host at the time of the infected feed. Ann. trop. Med. Parasit. 54, 341350.CrossRefGoogle ScholarPubMed
Willett, K. C. (1966) Development of the peritrophic membrane in Glossina (tsetse flies) and its relation to infection with trypanosomes. Exp. Parasit. 18, 290295.CrossRefGoogle Scholar
Williamson, J. (1956) The composition of tsetse fly saliva. I. A histochemical analysis. II. Analysis of amino acids and sugars by paper partition chromatography. Ann. trop. Med. Parasit. 50, 322–333, 334344.CrossRefGoogle Scholar