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Network analysis of impulse dyscontrol in mild cognitive impairment and subjective cognitive decline

Published online by Cambridge University Press:  15 February 2021

T. Saari Open the ORCID record for T. Saari [Opens in a new window] ,
E. E. Smith  and
Z. Ismail
T. Saari*
Affiliation:
Department of Neurology, University of Eastern Finland, Kuopio, Finland
E. E. Smith
Affiliation:
Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada
Z. Ismail
Affiliation:
Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada Department of Psychiatry, University of Calgary, Calgary, Alberta, Canada
*
Correspondence should be addressed to: T. Saari, University of Eastern Finland, Yliopistonranta 1B, FIN-70210Kuopio, Finland. Phone: +358 50 325 9130; Fax: 358 17 163539. Email: toni.saari@uef.fi.
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Abstract

Objectives:

To investigate conditional dependence relationships of impulse dyscontrol symptoms in mild cognitive impairment (MCI) and subjective cognitive decline (SCD).

Design:

A prospective, observational study.

Participants:

Two hundred and thirty-five patients with MCI (n = 159) or SCD (n = 76) from the Prospective Study for Persons with Memory Symptoms dataset.

Measurements:

Items of the Mild Behavioral Impairment Checklist impulse dyscontrol subscale.

Results:

Stubbornness/rigidity, agitation/aggressiveness, and argumentativeness were frequent and the most central symptoms in the network. Impulsivity, the fourth most central symptom in the network, served as the bridge between these common symptoms and less central and rare symptoms.

Conclusions:

Impulse dyscontrol in at-risk states for dementia is characterized by closely connected symptoms of irritability, agitation, and rigidity. Compulsions and difficulties in regulating rewarding behaviors are relatively isolated symptoms.

Keywords

impulse control disordersmild cognitive impairmentsubjective cognitive declinemild behavioral impairmentneuropsychiatric symptomsnetwork analysis
Type
Original Research Article
Information
International Psychogeriatrics , Volume 34 , Special Issue 6: Issue Theme: New Studies of Mild Cognitive Impairment , June 2022 , pp. 553 - 562
Copyright
© International Psychogeriatric Association 2021

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