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P59: Associations Between Smoking, Alcohol Consumption, Physical Activity and Depression in Middle-Aged Premenopausal and Postmenopausal Women

Published online by Cambridge University Press:  02 February 2024

Eunseo Heo ,
Hyewon Kim ,
Juhwan Yoo ,
Kyungdo Han ,
Maurizio Fava ,
David Mischoulon ,
Mi Jin Park  and
Hong Jin Jeon
Eunseo Heo
Affiliation:
Department of Psychiatry, Hanyang University Hospital, Seoul, South Korea
Hyewon Kim
Affiliation:
Department of Psychiatry, Hanyang University Hospital, Seoul, South Korea
Juhwan Yoo
Affiliation:
Department of Biomedicine and Health Science, The Catholic University of Korea, Seoul, South Korea
Kyungdo Han
Affiliation:
Department of Statistics and Actuarial Science, Soongsil University, Seoul, South Korea
Maurizio Fava
Affiliation:
Depression Clinical and Research Program, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States
David Mischoulon
Affiliation:
Depression Clinical and Research Program, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States
Mi Jin Park
Affiliation:
Department of Psychiatry, Depression Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea
Hong Jin Jeon
Affiliation:
Department of Psychiatry, Depression Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea Department of Health Sciences and Technology, Department of Medical Device Management and Research, and Department of Clinical Research Design and Evaluation, Samsung Advanced Institute for Health Sciences and Technology (SAIHST), Sungkyunkwan University, Seoul, South Korea

Abstract

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Background:

Changes in lifestyle factors are known to affect mood. However, there is insufficient evidence supporting the association between smoking, alcohol consumption, physical activity and depression in middle-aged women who are likely to experience rapid hormonal changes.

Methods:

We used a nationwide database of medical records in South Korea. 901,721 premenopausal and 943,710 postmenopausal women aged 40 years or older included in this study. Information on smoking, alcohol consumption, physical activity was identified from health examination data and followed up for the occurrence of depression using claims data.

Results:

Compared with never-smokers, ex-smokers and current smokers among premenopausal and postmenopausal women showed an increased risk of depression in a dose-dependent manner (aHR 1.13 for ex-smokers; aHR 1.23 for current smokers). Compared with non-drinkers, mild drinkers showed a decreased risk of depression (aHR 0.98 for premenopausal women; aHR 0.95 for postmenopausal women), and heavy drinkers showed an increased risk of depression both among premenopausal (aHR 1.20) and postmenopausal women (aHR 1.05). The risk of depression due to smoking and heavy alcohol consumption was higher in premenopausal women than in postmenopausal women. Compared with those who had not engaged in regular physical activity, those who had engaged showed a decreased risk of depression both among premenopausal (aHR 0.96) and postmenopausal women (aHR 0.95).

Conclusions:

Smoking and heavy alcohol consumption increased the risk of depression, and the increased risk was prominent in premenopausal than in postmenopausal women. Regular physical activity decreased the risk of depression both in premenopausal and postmenopausal women.

Type
Posters
Information
International Psychogeriatrics , Volume 35 , Issue S1 , December 2023 , pp. 156 - 157
Copyright
© International Psychogeriatric Association 2024