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Prevalence and comorbidities of dementia in Israel: A nationally representative cohort study

Published online by Cambridge University Press:  15 October 2018

A. Kodesh
A. Kodesh*
Affiliation:
Meuhedet Health Services, Mental Health, Tel Aviv, Israel Community Mental Health, University of Haifa, Haifa, Israel
*
Correspondence should be addressed to: A. Kodesh, Meuhedet Health Services, Mental Health, 36 Jabotinsky St., Tel Aviv 62287, Israel. Phone: 972-522674784; Fax: 972-3-5276707. Email: arad.k@meuhedet.co.il.
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Abstract

Information on the prevalence of dementia is rare in the Middle East, including dementia comorbidities with diabetes, ischemic heart disease (IHD), diabetes, and severe mental illnesses (SMI). This study aims to examine the 1-year prevalence of dementia and the aforementioned comorbidities in a representative national Israeli cohort aged 60 and above. The study design was a nationally representative cohort. The source sample comprised 122,829 persons aged 60 and above in 2015. The dementia group consisted of 8,153 patients (6.6%). The rate of dementia approximately doubled for every 5 years of maturation to the age of 84, and dropped thereafter. Dementia was significantly (P < 0.0001) more likely among women (N = 4,899, 7.4%) than men (N = 3,254, 5.7%). Based on multivariate logistic regression models, the group with dementia compared with the group without dementia had statistically significant (P < 0.001) lower odds of diabetes (OR = 0.78) and IHD (OR = 0.87), and significantly higher odds of SMI (OR = 4.96), accounting for age and gender. The prevalence of dementia delineated by age and gender in Israel resembles those found in other developed nations. Generally, dementia was associated with more SMI and less IHD and diabetes.

Keywords

epidemiologypsychogeriatricdementiaagingcomorbidities
Type
Brief Report
Information
International Psychogeriatrics , Volume 31 , Issue 7: Issue Theme: Diverse Approaches to Stemming Cognitive Decline , July 2019 , pp. 1059 - 1063
Copyright
© International Psychogeriatric Association 2018 

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References

Andreas, S. et al. (2017). Prevalence of mental disorders in elderly people: the European MentDis_ICF65+ study. British Journal of Psychiatry, 210, 125–131. doi: 10.1192/bjp.bp.115.180463.CrossRefGoogle ScholarPubMed
Bowirrat, A., Treves, T. A., Friedland, R. P. and Korczyn, A. D. (2001). Prevalence of Alzheimer’s type dementia in an elderly Arab population. European Journal of Neurology, 8, 119–123. doi: 10.1046/j.1468-1331.2001.00183.x.CrossRefGoogle Scholar
Green, R. C. et al. (2003). Depression as a risk factor for Alzheimer disease: the MIRAGE study. Archives of Neurology, 60, 753–759. doi: 10.1001/archneur.60.5.753.CrossRefGoogle ScholarPubMed
Jacobson, N. S. and Truax, P. (1991). Clinical significance: a statistical approach to defining meaningful change in psychotherapy research. Journal of Consulting and Clinical Psychology, 59, 12–19.CrossRefGoogle ScholarPubMed
Kodesh, A., Goldshtein, I., Gelkopf, M., Goren, I., Chodick, G. and Shalev, V. (2012). Epidemiology and comorbidity of severe mental illnesses in the community: findings from a computerized mental health registry in a large Israeli health organization. Social Psychiatry and Psychiatric Epidemiology, 47, 1775–1782. doi: 10.1007/s00127-012-0478-9.CrossRefGoogle Scholar
Larson, E. B., Reifler, B. V., Featherstone, H. J. and English, D. R. (1984). Dementia in elderly outpatients: a prospective study. Annals of Internal Medicine, 100, 417–423. doi: 10.7326/0003-4819-100-3-417.CrossRefGoogle ScholarPubMed
Matthews, F. E. et al. (2016). A two decade dementia incidence comparison from the Cognitive Function and Ageing Studies I and II. Nature Communications, 7, 11398. doi: 10.1038/ncomms11398.CrossRefGoogle ScholarPubMed
McCormick, W. C., Kukull, W. A., Van Belle, G., Bowen, J. D., Teri, L. and Larson, E. B. (1994). Symptom patterns and comorbidity in the early stages of Alzheimer’s disease. Journal of the American Geriatrics Society, 42, 517–521. doi: 10.1111/j.1532-5415.1994.tb04974.x.CrossRefGoogle ScholarPubMed
Prince, M., Bryce, R., Albanese, E., Wimo, A., Ribeiro, W. and Ferri, C. P. (2013). The global prevalence of dementia: a systematic review and meta-analysis. Alzheimer’s & Dementia, 9, 63–75. doi: 10.1016/j.jalz.2012.11.007.CrossRefGoogle Scholar
Prince, M. J. (2015). World Alzheimer Report 2015: The Global Impact of Dementia: An Analysis of Prevalence, Incidence, Cost and Trends. London: Alzheimer’s Disease International.Google Scholar
Schubert, C. C. et al. (2006). Comorbidity profile of dementia patients in primary care: are they sicker? Journal of the American Geriatrics Society, 54, 104–109. doi: 10.1111/j.1532-5415.2005.00543.x.CrossRefGoogle ScholarPubMed
Woodhead, C., Ashworth, M., Schofield, P. and Henderson, M. (2014). Patterns of physical co-/multi-morbidity among patients with serious mental illness: a London borough-based cross-sectional study. BMC Family Practice, 15, 117. doi: 10.1186/1471-2296-15-117.CrossRefGoogle ScholarPubMed
Wortmann, M. (2012). Dementia: a global health priority – highlights from an ADI and World Health Organization report. Alzheimer’s Research & Therapy, 4, 40. doi: 10.1186/alzrt143.Google ScholarPubMed
Wu, Y. T. et al. (2016). Dementia in western Europe: epidemiological evidence and implications for policy making. Lancet Neurology, 15, 116–124. doi: 10.1016/S1474-4422(15)00092-7.CrossRefGoogle ScholarPubMed
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