Hostname: page-component-78c5997874-m6dg7 Total loading time: 0 Render date: 2024-11-13T04:03:50.476Z Has data issue: false hasContentIssue false

Sedative hypnotic use among veterans with a newly reported mental health disorder

Published online by Cambridge University Press:  13 April 2016

Elizabeth A. DiNapoli
Affiliation:
VISN 4 Mental Illness Research, Education and Clinical Center (MIRECC), VA Pittsburgh Healthcare System, Pittsburgh, PA, USA Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Adam D. Bramoweth*
Affiliation:
VISN 4 Mental Illness Research, Education and Clinical Center (MIRECC), VA Pittsburgh Healthcare System, Pittsburgh, PA, USA Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Christopher Cinna
Affiliation:
VISN 4 Mental Illness Research, Education and Clinical Center (MIRECC), VA Pittsburgh Healthcare System, Pittsburgh, PA, USA Center for Social and Public Policy, Duquesne University, Pittsburgh, PA, USA
John Kasckow
Affiliation:
VISN 4 Mental Illness Research, Education and Clinical Center (MIRECC), VA Pittsburgh Healthcare System, Pittsburgh, PA, USA Center for Health Equity Research and Promotion, VA Pittsburgh Healthcare System, Pittsburgh, PA, USA Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
*
Correspondence should be addressed to: Adam D. Bramoweth, PhD, VA Pittsburgh Healthcare System, Research Office Building (151R), University Drive, Pittsburgh, PA 15240, USA. Phone: +412-360-2806; Fax: +412-360-2369. Email: Adam.Bramoweth@va.gov.

Abstract

Background:

This study compared sedative hypnotic use by type of mental health diagnosis and determined factors associated with use among older veterans (65+ years) with a newly reported mental health disorder.

Methods:

This study used data from veterans who received primary care services at VA Pittsburgh Healthcare System (VAPHS) from January 1, 2007 to December 31, 2011 (n = 879).

Results:

Sedative hypnotics were commonly used in older veterans within 12-months following a newly reported mental health disorder (19.9%), particularly amongst those with insomnia (41.7%). The number of newly reported mental health disorders was a significant factor associated with sedative hypnotic use, with the odds of use increasing by more than 200% in older adults with two newly reported disorders compared to those with one newly reported mental health disorder.

Conclusions:

Continued efforts are needed to improve provider and patient awareness of the risks associated with sedative hypnotic use in older adults, as well as to increase access to and receipt of non-pharmacological mental health treatments for this vulnerable population.

Type
Research Article
Copyright
Copyright © International Psychogeriatric Association 2016 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Allain, H., Bentue-Ferrer, D., Polard, E., Akwa, Y. and Patat, A. (2005). Postural instability and consequent falls and hip fractures associated with use of hypnotics in the elderly: a comparative review. Drugs Aging, 22, 749765.CrossRefGoogle ScholarPubMed
Ancoli-Israel, S. (2000). Insomnia in the elderly: a review for the primary care practitioner. Sleep, 23, S23–30.Google ScholarPubMed
American Medical Directors Association. (2006). Clinical Practice Guidelines: Sleep Disorders. Columbia, MD: American Medical Directors Association.Google Scholar
Barbone, F. et al. (1998). Association of road-traffic accidents with benzodiazepine use. The Lancet, 352, 13311336.CrossRefGoogle ScholarPubMed
Bastien, C. H., LeBlanc, M., Carrier, J. and Morin, C. M. (2003). Sleep EEG power spectra, insomnia, and chronic use of benzodiazepines. Sleep, 26, 313317.Google Scholar
Blazer, D., Hybels, C., Simonsick, E. and Hanlon, J. T. (2000). Sedative, hypnotic, and antianxiety medication in an aging cohort over ten years: a racial comparison. Journal of American Geriatric Society, 48, 10731079.CrossRefGoogle Scholar
Campanelli, C. M. (2012). American geriatrics society updated beers criteria for potentially inappropriate medication use in older adults: the American geriatrics society 2012 beers criteria update expert panel. Journal of American Geriatrics Society, 60, 616631.Google Scholar
Carr, M. (2005). Sedative and psychotropic mediations. Nursing BC, 37, 2931.Google Scholar
Cohen, J. (1988). Statistical Power Analysis for the Behavioral Sciences, 2nd edn. Hillsdale, NJ: Lawrence Earlbaum Associates.Google Scholar
Cuijpers, P., van Straten, A. and Smit, F. (2006). Psychological treatment of late-life depression: a meta-analysis of randomized controlled trails. International Journal of Geriatric Psychiatry, 21, 11391149.Google Scholar
Dinnen, S., Simiola, V. and Cook, J. M. (2015). Post-traumatic stress disorder in older adults: a systematic review of the psychotherapy treatment literature. Aging & Mental Health, 19, 144150.CrossRefGoogle ScholarPubMed
FDA requiring lower recommended dose for certain sleep drugs containing zolpidem [press release]. Silver Spring, MD; 2013.Google Scholar
Fu, A. Z., Jiang, J. Z., Reeves, J. H., Fincham, J. E., Liu, G. G. and Perri, M. 3rd. (2007). Potentially inappropriate medication use and healthcare expenditures in the US community-dwelling elderly. Medical Care, 45, 472476.Google Scholar
Glass, J., Lanctot, K. L., Herrmann, N., Sproule, B. A. and Busto, U. E. (2005). Sedative hypnotics in older people with insomnia: meta-analysis of risks and benefits. British Medical Journal, 331, 11691176.Google Scholar
James, S. P. and Mendelson, W. B. (2004). The use of trazodone as a hypnotic: a critical review. Journal of Clinical Psychiatry, 65, 752755.Google Scholar
Jorm, A. F., Grayson, D., Creasey, H., Waite, L. and Broe, G. A. (2000). Long-term benzodiazepine use by elderly people living in the community. Australian and New Zealand Journal of Public Health, 24, 710.CrossRefGoogle ScholarPubMed
Kessler, R. C. et al. (2014). Thirty-day prevalence of DSM-IV mental disorders among non-deployed soldiers in the U.S. army: results from the army study to assess risk and resilience in service members (Army STARRS). Journal of American Medical Association, 71, 504513.Google Scholar
Kripke, D. F., Langer, R. D. and Kline, L. E. (2012). Hypnotics’ association with mortality or cancer: a matched cohort study. British Medical Journal Open, 2, 18.Google Scholar
Lechevallier-Michel, N., Berr, C. and Fourrier-Reglat, A. (2005). Incidence and characteristics of benzodiazepine use in the elderly cohort: the EVA study. Therapie, 60, 561566.Google Scholar
Lindsey, P. L. (2009). Psychotropic medication use among older adults: what all nurses need to know. Journal of Gerontological Nursing, 35, 2838.Google Scholar
Mendelson, W. B. (1995). Effects of flurazepam and zolpidem on the perception of sleep in insomniacs. Sleep, 18, 9296.Google Scholar
Office of the Under Secretary of Defense, Personnel and Readiness. (2012). Population Representation in the Military Services: Fiscal Year 2011 Summary Report. Available at: https://www.cna.org/pop-rep/2011/summary/summary.pdf; last accessed 9 February 2016.Google Scholar
Pugh, M. J. V. et al. (2005). Potentially inappropriate prescribing in elderly veterans: are we using the wrong drug, wrong dose, or wrong duration?. Journal of the American Geriatrics Society, 53, 12821289.Google Scholar
Pugh, M. J. V., Hanlon, J. T., Zeber, J. E., Bierman, A., Cornell, J. and Berlowitz, D. R. (2006). Assessing potentially inappropriate prescribing in the elderly Veterans Affair population using the HEDIS 2006 Quality Measure. Journal of Managed Care Pharmacy, 12, 537545.Google Scholar
Sabrina, P., Dufouil, C. and Alperovitch, A. (2002). Long-term benzodiazepine use and cognitive decline in the elderly: the epidemiology of vascular aging study. Journal of Clinical Psychopharmacology, 22, 285293.Google Scholar
Schonfeld, L. et al. (2000). Cognitive-behavioral treatment of older veterans with substance abuse problems. Journal of Geriatric Psychiatry and Neurology, 13, 124129.Google Scholar
Schutte-Rodin, S., Broch, L., Buysse, D., Dorsey, C. and Sateia, M. (2008). Clinical guideline for the evaluation and management of chronic insomnia in adults. Clinical Sleep Medicine, 4, 487504.CrossRefGoogle ScholarPubMed
Simon, G. E. and Ludman, E. J. (2006). Outcome of new benzodiazepine prescriptions to older adults in primary care. General Hospital Psychiatry, 28, 374378.Google Scholar
Sivertsen, B. et al. (2006). Cognitive behavioral therapy vs Zopiclone for treatment of chronic primary insomnia in older adults: a randomized controlled trial. Journal of the American Medical Association, 295, 28512858.CrossRefGoogle ScholarPubMed
Smith, M. T. et al. (2002). Comparative meta-analysis of pharmacotherapy and behavior therapy for persistent insomnia. American Journal of Psychiatry, 159, 511.Google Scholar
Stuck, A. E., Beers, M. H., Steiner, A., Aronow, H. U., Rubenstein, L. Z. and Beck, J. C. (1994). Inappropriate medication use in community-dwelling older persons. Archives of Internal Medicine, 154, 21952200.CrossRefGoogle Scholar
Thorp, S. R., Ayers, C. R., Nuevo, R., Stoddard, J. A., Sorrell, J. T. and Wetherell, J. L. (2009). Meta-analysis comparing different behavioral treatments for late-life anxiety. American Journal of Geriatric Psychiatry, 17, 105115.Google Scholar
Troxel, W. M. et al. (2015). Sleep in the Military: Promoting Healthy Sleep Among U.S. Servicemembers. Santa Monica, CA: RAND Corporation.Google ScholarPubMed
Zisselman, M. H., Rovner, B. W., Yuen, E. J. and Louis, D. Z. (1996). Sedative-hypnotic use and increased hospital stay and costs in older people. Journal of American Geriatric Society, 44, 13711374.Google Scholar