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Risperidone induced periorbital oedema

Published online by Cambridge University Press:  13 June 2014

Vikrant Bajaj ,
Ankur Srivastava ,
Somnath Sengupta ,
Saurabh Mehrotra ,
Shaveta Vedi  and
Prashant Pathak
Vikrant Bajaj*
Affiliation:
Institute of Human Behaviour & Allied Sciences (IHBAS), Dilshad Garden, Delhi, India
Ankur Srivastava
Affiliation:
Institute of Human Behaviour & Allied Sciences (IHBAS), Dilshad Garden, Delhi, India
Somnath Sengupta
Affiliation:
Institute of Human Behaviour & Allied Sciences (IHBAS), Dilshad Garden, Delhi, India
Saurabh Mehrotra
Affiliation:
Institute of Human Behaviour & Allied Sciences (IHBAS), Dilshad Garden, Delhi, India
Shaveta Vedi
Affiliation:
Institute of Human Behaviour & Allied Sciences (IHBAS), Dilshad Garden, Delhi, India
Prashant Pathak
Affiliation:
Institute of Human Behaviour & Allied Sciences (IHBAS), Dilshad Garden, Delhi, India
*
*Correspondence E-mail: drvikrantbajaj@yahoo.co.in
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Abstract

Antipsychotic medications are associated with adverse cutaneous reactions (ACRs) in approximately 2–3% of patients. We present three cases of possible risperidone induced periorbital oedema in the absence of any other systemic or local cause responsible for the oedema. The development of periorbital oedema after the initiation of risperidone therapy, and disappearance after the discontinuation of this drug, suggests a possible causal relationship between periorbital oedema and risperidone. To our knowledge, there are very few reports of risperidone therapy and development of periorbital oedema. Risperidone is a valid and effective choice amongst antipsychotic medications, but these cases call for caution regarding ACRs at the time of prescribing.

Keywords

RisperidoneSchizophreniaPeriorbital oedema
Type
Case reports
Information
Irish Journal of Psychological Medicine , Volume 27 , Issue 4 , December 2010 , pp. 216 - 217
Copyright
Copyright © Cambridge University Press 2010

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References

1.Acmorran, W, Krahn, L.Adverse Cutaneous Reactions to Psychotropics drugs. Psychosomatics 1997; 38: 413–422.CrossRefGoogle Scholar
2.Katz, Y, Goldberg, N, Kivity, S.Localised periorbital edema induced by aspirin. Allergy 1993; 48[5]: 366–369.CrossRefGoogle ScholarPubMed
3.Palungwachira, P, Palungwachira, P, Ogawa, H.Localised periorbital edema induced by Ibuprofen. J Dermatol 2005; 32(12): 969–971.CrossRefGoogle ScholarPubMed
4.Akkaya, C, Sarandol, A, Aydogan, K.Urticaria and angio-oedema due to ziprasidone. J Psychopharmacol 2007; 21(5): 550–552.CrossRefGoogle ScholarPubMed
5.Mishra, B, Sahoo, S, Sarkar, S, Akhtar, S.Clozapine induced angioneurotic edema. Gen Hosp Psychiatry 2007; 29: 78–80.CrossRefGoogle ScholarPubMed
6.Kaizu, K, Abe, N.Drug induced edema. Nippon Rinsho 2005 Jan; 63[1]: 102–106.Google ScholarPubMed
7.Baldassano, CF, Ghaemi, SN.Generalised edema with risperidone: divalproex treatment. J Clin Psychiatry 1996; 57(9): 422.Google Scholar
8.Sanders, R, Lehrer, D.Edema associated with addition of risperidone to valproate treatment. J Clin Psychiatry 1998; 12: 689–670.CrossRefGoogle Scholar
9.Cooney, C, Nagy, A.Angio-oedema associated with risperidone. BMJ 1995; 311[7014]: 1204.CrossRefGoogle ScholarPubMed
10.Erken, DD, Kilico, O, Okay, IT, Dilbaz, N.A case of angioedema due to risperidone. Bull Clin Psychopharmacol 2007; 17: 198–202.Google Scholar
11.Ravasia, S.Risperidone induced edema. Can J Psychiatry 2001 June; 46(5): 453–454.CrossRefGoogle ScholarPubMed