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Childhood ‘risk characteristics’ and the schizophrenia spectrum prodrome

Published online by Cambridge University Press:  13 June 2014

Mark Morris
Affiliation:
The Upper Surgery, 27 Lemon Street, Truro, Cornwall, TR1 2LS, England
Robert Macpherson
Affiliation:
Wotton Lawn, Horton Road, Gloucester, GL1 3WL, England

Abstract

This review identifies similarities between behavioural indicators of children with future schizophrenia-spectrum disorders and prodromal symptoms in the first episode of schizophrenia. An alternative concept of prodrome is described with implications for early recognition, monitoring and intervention of individuals at risk of future schizophrenia spectrum disorders.

Type
Reviews
Copyright
Copyright © Cambridge University Press 2001

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References

1.Parnas, Jet al. Lifetime DSM III R diagnostic outcomes in offspring of schizophrenic mothers: Results from the Copenhagen high risk study. Arch Gen Psychiat 1993; 50: 707–14.CrossRefGoogle ScholarPubMed
2.Olin, SSet al. Childhood behavioural precursors of schizotypal personality disorder. Schizophrenia Bulletin 1994; 23: 93103.CrossRefGoogle Scholar
3.Olin, SS, John, RS, Mednick, SA. Assessing the predictive value of teacher reports in a high risk sample for schizophrenia: A ROC analysis. Schizophrenia Research 1995; 16:5366.CrossRefGoogle Scholar
4.Tyrka, ARet al. The latent structure of schizotypy: I. Premorbid indicators of a taxon of individuals at risk for schizophrenia spectrum disorders. J Abnormal Psychology 1995; 104: 173–83.CrossRefGoogle ScholarPubMed
5.Watt, NF. Longitudinal changes in the social behaviour of children hospitalised for schizophrenia as adults. J Nerv Ment Disorders 1972; 155: 4254.CrossRefGoogle ScholarPubMed
6.Watt, NF. Patterns of childhood social development in adult schizophrenics. Arch Gen Psychiat 1978; 35: 160–5.CrossRefGoogle ScholarPubMed
7.Watt, NF, Lubenksky, AW. Childhood roots of schizophrenia. J Consult Clin Psych 1976; 44: 363–75.CrossRefGoogle ScholarPubMed
8.Jones, Pet al. Child developmental risk factors for adult schizophrenia in the British 1946 birth cohort. Lancet 1994; 344: 1398–402.CrossRefGoogle ScholarPubMed
9.Malmberg, Aet al. Premorbid adjustment and personality in people with schizophrenia. Br J Psychiat 1998; 172: 308–13.CrossRefGoogle ScholarPubMed
10.Yung, A, McGorry, P. The prodromal phase of first episode psychosis: Past and current conceptualisations. Schizophrenia Bulletin 1996; 22: 353–71.CrossRefGoogle Scholar
11.American Psychiatric Association. (1987) Diagnostic and Statistical Manual of Mental Disorders (3rd Ed, revised) (DSM-III-R). Washington, DC: APA.Google Scholar
12.Meehl, PE. Schizotaxia, schizotypy, schizophrenia. Am Psych 1962; 17: 827–38.CrossRefGoogle Scholar
13.Meehl, PE. Schizotaxia revisited. Arch Gen Psychiat 1989; 46: 935944.CrossRefGoogle ScholarPubMed
14.Meehl, PE. Toward an integrated theory of schizotaxia, schizotypy and schizophrenia. J Personality Disorders 1990; 4, 199.CrossRefGoogle Scholar
15.Jones, PBet al. Cerebral ventricle dimensions as risk factors for schizophrenia and affective psychosis. An epidemiological approach to analysis. Psych Med 1994; 24: 9951011.CrossRefGoogle ScholarPubMed
16.Kirov, Get al. Do obstetric complications cause gender differences in schizophrenia? Schizophrenia Research 1996; 20: 117–23.CrossRefGoogle Scholar
17.Rapoport, JLet al. Childhood-Onset Schizophrenia. Progressive ventricular change during adolescence. Arch Gen Psychiat 1997; 54: 897903.CrossRefGoogle ScholarPubMed
18.Bertolino, Aet al. Common pattern of cortical pathology in Childhood-Onset and Adult-Onset Schizophrenia as identified by Proton Magnetic Resonance Spectroscopic Imaging. Am J Psychiat 1998; 155: 1376–83.CrossRefGoogle ScholarPubMed
19.Birchwood, A, McGorry, P, Jackson, H. Early Intervention in Schizophrenia. Br J Psychiat 1997; 170: 25.CrossRefGoogle ScholarPubMed
20.Olin, SSet al. School teacher ratings predictive of psychiatric outcome 25 years later. Br J Psychiat 1998; 172 (suppl.33): 713.CrossRefGoogle ScholarPubMed
21.Yung, ARet al. Monitoring and care of young people at incipient risk of psychosis. Schizophrenia Bulletin 1996; 22: 283303.CrossRefGoogle ScholarPubMed
22.Tsuang, MTet al. Treatment of nonpsychotic relatives of patients with schizophrenia: Four case studies. Biological Psychiatry 1999; 45: 14121418.CrossRefGoogle ScholarPubMed