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Clozapine induced myocarditis: a case report and literature review

Published online by Cambridge University Press:  13 June 2014

Sunday O Okereke ,
Wan MY Mohd Abdoh  and
Bernadette M Murphy
Sunday O Okereke
Affiliation:
Department of Psychiatry, Adelaide and Meath Hospital including the National Children's Hospital, Tallaght, Dublin 24, Ireland
Wan MY Mohd Abdoh
Affiliation:
Department of Psychiatry, Adelaide and Meath Hospital including the National Children's Hospital, Tallaght, Dublin 24, Ireland
Bernadette M Murphy*
Affiliation:
Department of Psychiatry, Adelaide and Meath Hospital including the National Children's Hospital, Tallaght, Dublin 24, Ireland
*
*Correspondence E-mail: bcantillonmurphy@hotmail.com
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Abstract

Clozapine, the drug of choice for treatment resistant schizophrenia, has a range of serious cardiac side-effects. This paper describes a fatal case of myocarditis in a 48 year old man four weeks after starting clozapine. In particular, this case illustrates how incipient the disorder can be and the need for a high level of suspicion. Difficulties in diagnosing clozapine induced myocarditis and ways to minimise its risk are also discussed.

Keywords

ClozapineMyocarditisSchizophrenia
Type
Case Reports
Information
Irish Journal of Psychological Medicine , Volume 26 , Issue 3 , September 2009 , pp. 147 - 148
Copyright
Copyright © Cambridge University Press 2009

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