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Complications of verapamil in psychiatry

Published online by Cambridge University Press:  13 June 2014

Kenneth R Kaufman
Kenneth R Kaufman*
Affiliation:
Department of Psychiatry, UMDNJ-Robert Wood Johnson Medical School, 675 Hoes Lane, Piscataway, New Jersey, 08901, USA
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Abstract

Effectiveness of verapamil as a psychotropic and verapamil toxicity when used as a psychotropic are presented in this case study with literature review.

Keywords

Affective disordersVerapamilToxicityCimetidine
Type
Brief Reports
Information
Irish Journal of Psychological Medicine , Volume 13 , Issue 3 , September 1996 , pp. 100 - 101
Copyright
Copyright © Cambridge University Press 1996

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References

1.Post, RM. Approaches to treatment-resistant bipolar affectively ill patients. Clin Neuropharm 1988; 11(2): 93–104.CrossRefGoogle ScholarPubMed
2.Gerner, RM. Treatment of acute mania. Psychiatric Clinics of North America 1993; 16(3): 443–60.CrossRefGoogle ScholarPubMed
3.Post, RM, Uhde, TW, Roy-Byrne, PP, Joffe, RT. Correlates of antimanic response to carbamazepine. Psychiat Res 1987; 21: 71–83.CrossRefGoogle ScholarPubMed
4.McElroy, SL, Keck, PE, Pope, HG, Hudson, JI. Valproate in the treatment of bipolar disorder: literature review and clinical guidelines. J of Clin Psychopharm 1992; 12:42S–52S.CrossRefGoogle ScholarPubMed
5.Chouinard, G, Young, SN, Annable, L. Antimanic effects of clonazepam. Biol Psychiat 1983; 18:451–66.Google ScholarPubMed
6.Dubovsky, SL. Calcium antagonists in manic-depressive illness. Neuropsychobiology 1993; 27: 184–92.CrossRefGoogle ScholarPubMed
7.Carman, JS, Wyatt, RJ. Calcium: bivalent cation in the bivalent psychoses. Biol Psychiat 1979; 14: 295–336.Google ScholarPubMed
8.Mathis, P, Schmitt, L, Moron, P. Efficacite du verapamil dans les acces maniaques. L'Encephale 1988; XIV: 127–32.Google Scholar
9.Dubovsky, SL, Murphy, J, Christiano, J, Lee, C. The calcium second messenger system in bipolar disorders: data supporting new research directions. J of Neuropsychiat and Clin Neurosci 1992; 4: 3–14.Google ScholarPubMed
10.Schou, M, Mellerup, ET, Rafaelsen, OJ. Mode of action of lithium. in Van, Praag HM, Lader, MH, Rafaelsen, OJ, Sachar, EJ, eds. Handbook of biological psychiatry. New York: Marcel Decker, 1981: 805–24.Google Scholar
11.Messing, RO, Carpenter, CL, Greenberg, DA. Mechanism of calcium channel inhibition by phenytoin: comparison with classical calcium channel antagonists. J of Pharm and Exp Ther 1985; 235: 407–11.Google ScholarPubMed
12.Crowder, JM, Bradford, HF. Common anticonvulsants inhibit Ca2+ uptake and amino acid neurotransmitter release in vitro. Epilepsia 1987; 28(4): 378–82.CrossRefGoogle ScholarPubMed
13.Taft, WC, Goldenring, JR, DeLorenzo, RJ. Molecular mechanisms of neuronal excitability: possible involvement of CaM kinase II in seizure activity. in Ehrlich, YH, Lenox, RH, Kornecki, E, Berry, WO, eds. Molecular mechanisms of neuronal responsiveness. New York: Plenum, 1987: 409–24.CrossRefGoogle Scholar
14.Franceschetti, S, Hamon, B, Heinemann, U. The action of valproate on spontaneous epileptiform activity in the absence of synaptic transmission and on evoked changes in [Ca2+]o and [K+]o in the hippocampal slice. Brain Res 1986; 386: 1–11.CrossRefGoogle Scholar
15.Taft, WC, DeLorenzo, RJ. Micromolar-affinity benzodiazepine receptors regulate voltage sensitive calcium channels in nerve terminal preparations. Proc Nat Acad of Sci 1984; 81(10): 3118–22.CrossRefGoogle ScholarPubMed
16.Matlib, MA, Doane, JD, Sperelakis, N, Riccippo-Neto, F. Clonazepam and diltiazem both inhibit sodium-calcium exchange of mitochondria, but only diltiazem inhibits the slow action potentials of cardiac muscles. Biochem and Biophys Res Comm 1985; 128: 290–6.CrossRefGoogle ScholarPubMed
17.Drago, F, Valeris, C, Clementi, G, Scapagnini, U. Effects of flunarizine on experimentally induced convulsions in animals. Fun Neur 1986; 1(4): 529–32.Google ScholarPubMed
18.Ots, ME, Yaksh, TL, Anderson, RE, Sundt, TM. Effect of dihydropyridines and diphenylalkylamines on pentylenetetrazol-induced seizures and cerebral blood flow in cats. J of Neurosurg 1987; 67(3): 406–13.CrossRefGoogle ScholarPubMed
19.Larkin, JG, McKee, PJW, Blacklaw, J, Thompson, GG, Morgan, PC, Brodie, MJ. Nimodipine in refractory epilepsy: a placebo-controlled, add-on study. Epilepsy Res 1991;9:71–7.CrossRefGoogle ScholarPubMed
20.Xie, JT, Li, CL. Induction and termination of after-depolarisations and triggered arrhythmias by drugs in cat heart in vivo. Meth and Find in Exp and Clin Pharm 1992; 14(5): 347–54.Google Scholar
21.Meerson, FZ, Gimrikh, EO, Gutsol, LI, Popov, SV, Plekhanov, IG. The antiarrhythmic efficacy of sodium valproate. Kardiologiya 1992; 32: 19–21.Google ScholarPubMed
22.Pazzaglia, PJ, Post, RM, Ketter, TA, George, MS, Marangell, LB. Preliminary controlled trial of nimodipine in ultra-rapid cycling affective dysregulation. Psychiat Res 1993; 49: 257–72.CrossRefGoogle ScholarPubMed
23.Mikus, G, Eichelbaum, M, Fischer, C, Gumulka, S, Klotz, U, Kroemer, HK. Interaction of verapamil and cimetidine: stereochemical aspects of drug metabolism, drug disposition and drug action. J of Pharm and Exp Ther 1990; 253(3): 1042–8.Google ScholarPubMed
24.Rosansky, SJ. Verapamil toxicity – treatment with hemoperfusion. Ann of Intern Med 1991; 114(4): 340–1.CrossRefGoogle ScholarPubMed