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Positron emission tomography in the study of neuropsychiatric disorders – its uses and potential

Published online by Cambridge University Press:  13 June 2014

Raymond J Dolan
Raymond J Dolan*
Affiliation:
The National Hospital, Queen Square WCl, Senior Lecturer, The Royal Free Hospital, Pond Street NW3
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Abstract

PET represents the most powerful tool available for the measurement of in-vivo brain function. The basic principles of the technique and its application to the study of brain energy metabolism and neuroreceptor function are described by reference to findings from clinical studies of cerebral metabolism in neurological and psychiatric disorders. The extension of such resting state investigations by the application of activation paradigms in dynamic studies is discussed. The potential of PET as a tool to investigate neuroreceptor function is outlined in the context of preliminary findings from studies of dopaminergic function in schizophrenic patients.

Keywords

Positron Emission TomographyNeuropsychiatry: SchizophreniaAffective Disorder
Type
Review Articles
Information
Irish Journal of Psychological Medicine , Volume 6 , Issue 2 , September 1989 , pp. 81 - 88
Copyright
Copyright © Cambridge University Press 1989

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