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Resolution of panic disorder during pregnancy

Published online by Cambridge University Press:  13 June 2014

Stephen Curran
Affiliation:
Academic Unit of Psychiatry, St. James's University Hospital, Leeds, LS9 7TF, England
Terry E Nelson
Affiliation:
High Royds Hospital, Leeds, LS29 6AQ, England
R John Rodgers
Affiliation:
Department of Psychology, University of Leeds, LS2 9JT, England

Abstract

A patient with severe long-standing panic disorder who made a full recovery whilst pregnant, only to relapse during the postpartum period, is presented. Sex steroids may have a role in the aetiology and management of panic disorder. This is potentially an important area which requires further research.

Type
Case Reports
Copyright
Copyright © Cambridge University Press 1995

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References

1.Stein, D, Hanukoglu, A, Blank, S, Elizur, A. Cyclic psychosis associated with the menstrual cycle. Br J Psychiatry 1993; 163: 824–8.CrossRefGoogle ScholarPubMed
2.Seeman, MV, Lang, M. The role of oestrogens in schizophrenia gender differences. Schizophren Bull 1990; 16; 185–95.CrossRefGoogle ScholarPubMed
3.Kendell, RE, Chalmers, L, Platz, C. The epidemiology of puerperal psychoses. Br J Psychiatry 1987; 150: 662–73.CrossRefGoogle ScholarPubMed
4.Henderson, AF, Gregoire, AJ, Kumar, RD, Studd, JW. Treatment of severe postnatal depression with oestradiol skin patches. Lancet 1991; 338: 816–7.CrossRefGoogle ScholarPubMed
5.Studd, JW, Watson, N, Henderson, AF. Oestrogen therapy for the menopause. Br J Psychiatry 1990; 157: 931–2.CrossRefGoogle ScholarPubMed
6.Taylor, M, Kumar, R. Neuroleptics, oestrogen, post-partumpsychiatric disturbance and movement disorder; a case report. J Psychopharmacol 1994; 8(2): 134–5.CrossRefGoogle ScholarPubMed
7.Guyton, AC. Textbook of Medical Physiology (8th ed). WB Saunders & Co., London, 1991.Google Scholar
8.Villeponteaux, VA, Lydiard, RB, Laraia, MT, Stuart, GW, Ballenger, JC. The effects of pregnancy on preexisting panic disorder. J Clin Psychiatry 1992; 53: 201–3.Google ScholarPubMed
9a.Klein, DF. False suffocation alarms, spontaneous panics and related conditions; An integrative hypothesis. Arch General Psychiatry 1993; 50: 306–17.CrossRefGoogle ScholarPubMed
9b.APA. Diagnostic and Statistical Manual of Mental Disorders3rd rev ed. APA: Washington (DC), 1987.Google Scholar
10.Nutt, D, Lawson, C. Panic attacks; a neurochemical overview of models and mechanisms. Br J Psychiatry 1992; 160: 165–78.CrossRefGoogle ScholarPubMed
11.Kukumberg, P, Strecko, A. Increased neuronal excitability in panic disorder. Br J Psychiatry 1993; 163: 839–40.CrossRefGoogle ScholarPubMed
12.Greenstein, BD, Adcock, IM. Oestrogen receptors and effects of oestradiol administration on mRNA synthesis in the limbic system of the neonatal female rat. J Endocrinology 1989; 120(1): 83–8.CrossRefGoogle ScholarPubMed
13.Giordano, AL, Ahdieh, HB, Mayer, AD, Siegel, HI, Rosenblatt, JS. Cytosol and nuclear oestrogen receptor binding in the preoptic area and hypothalamus of female rats during pregnancy and ovariectomised, nulliparous rats after steriod priming; correlation with maternal behaviour. Hormones and Behaviour 1990; 24(2): 232–55.CrossRefGoogle Scholar
14.Fujimoto, N, Watanabe, H, Ito, A. Direct up-regulation of oestrogen receptor by tri-iodothyronine in rat pituitary tumour MtT/F84. Endocrinologica Japonica 1991; 38(4): 405–12.CrossRefGoogle Scholar
15.Pedersen, EB, O'Keefe, JA, Handa, RJ, Castro, AJ. Oestrogen receptors are present in neocortical transplants. Journal of Neural Transplantation and Plasticity 1992; 3(2-3): 135–8.CrossRefGoogle ScholarPubMed
16.Hafner, H, Behrens, S, De Vry, J, Gattaz, WF. Oestradiol enhances the vulnerability threshold for schizophrenia in women by an early effect on dopaminergic neurotransmission. Evidence from an epidemiological study and from animal experiments. Eur Arch Psychiatr Clin Neuroscience 1991; 241: 658.CrossRefGoogle ScholarPubMed
17.Clarke, WP, Goldfarb, J. Oestrogen enhances a 5-HT1A response in hippocampal slices from female rats. Eur J Pharmacol 1989; 160(1): 195–7.CrossRefGoogle ScholarPubMed
18.Rupprecht, R, Reul, JMHM, Trapp, T, van Steensel, B, Wetzel, C, Damm, K, Zieglgansberger, W, Holsoer, F. Progesterone receptor mediated effects of neuroactive steroids. Neuron 1993; 11: 523–30.CrossRefGoogle ScholarPubMed
19.Halbreich, U, Endicott, J. Methodological issues in studies of premenstrual changes. Psychoneuroendocrinology 1985; 10: 1523.CrossRefGoogle ScholarPubMed
20.Dennerstein, L, Spencer-Gardner, C, Gotts, G, Brown, JB, Smith, MA, Burrows, GD. Progesterone and premenstrual syndrome: a double-blind crossover trial. British Medical Journal 1985; 290: 1617–621.CrossRefGoogle ScholarPubMed
21.Carter-Little, B, Matta, RJ, Zahn, TP. Physiological and psychological effects of progesterone in men. J Nerv Ment Dis 1983; 159: 256–67.CrossRefGoogle Scholar
22.Bitran, D, Hilvers, RJ, Kellogg, CK. Ovarian status modulates the anxiety potency of diazepam and the efficacy of gamma-aminobutyric acid-benzodiazepine receptor-mediated chloride ion transport. Behavioural Neuroscience 1991; 105: 653–62.CrossRefGoogle Scholar
23.Zimmerberg, B, Farley, MJ. Sex differences in anxiety behaviour in rats: role of gonadal hormones. Physiology and Behaviour 1993; 54: 1119–24.CrossRefGoogle ScholarPubMed
24.Magnussen, I, Tonder, K, Engback, F. Paroxetine, a potent selective long acting ihibitor of synaptosomal serotonin uptake in mice. J Neural Transmission 1982; 55:217–66.CrossRefGoogle Scholar
25.Sheehan, DV, Raj, BA, Trehan, RR, Knapp, EL. Serotonin in panic disorder and social phobia. Intern Clin Psychopharmacol 1993; 8 (Suppl): 6377.CrossRefGoogle ScholarPubMed