Hostname: page-component-78c5997874-m6dg7 Total loading time: 0 Render date: 2024-11-11T08:12:25.119Z Has data issue: false hasContentIssue false
  • English
  • Français

Sexual dysfunction and antidepressants: a review with emphasis on treatment

Published online by Cambridge University Press:  13 June 2014

Maeve Kenny  and
Faraz Jabbar
Maeve Kenny
Affiliation:
Mater Misericordiae University Hospital, Eccles St, Dublin 7, Ireland
Faraz Jabbar
Affiliation:
Mater Misericordiae University Hospital, Eccles St, Dublin 7, Ireland
Get access Rights & Permissions [Opens in a new window]

Abstract

Sexual dysfunction (SD) is widely recognised as a potential side-effect of antidepressant therapy. SD has been reported with all classes of antidepressants (MAOIs, TCAs, SSRIs, SNRIs and newer antidepressants) in patients with depression and anxiety disorders. Increased attention has been directed at the SD produced by antidepressants; not only because its initial prevalence was underestimated but also because of the adverse impact that these side-effects can have on treatment compliance. Although SD is an important adverse effect of antidepressant medication, patients tend to be reluctant to report them if not directly questioned. This suggests that consideration of the doctor-patient relationship is needed when deciding on an appropriate treatment plan.

Type
Review
Information
Irish Journal of Psychological Medicine , Volume 28 , Issue 3 , September 2011 , pp. 165 - 167
Copyright
Copyright © Cambridge University Press 2011

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Montgomery, S, Baldwin, A, Riley, A. Antidepressant Medications: A Review of the evidence for drug-induced sexual dysfunction. J Affect Dis 2000; 69(2): 119–140.CrossRefGoogle Scholar
2.Rivas-Vazquez, R, Blais, M, Rey, G, Rivas-Vazquez, A. Sexual Dysfunction associated with antidepressant treatment. Prof Psychol Res Pract 2000; 31(6): 641–651.CrossRefGoogle Scholar
3.Serretti, A, Chiesa, A. Treatment-emergent sexual dysfunction related to antidepressants: A meta-analysis. J Clin Psychopharmacol 2009; 29(3): 259–266.CrossRefGoogle ScholarPubMed
4.Lee, K, Lee, Y, Nam, Jet al.Antidepressant-Induced sexual dysfunction among newer antidepressants in a naturalistic setting. Psychiat Invest 2010; 7(1): 55–59.CrossRefGoogle Scholar
5.Osvath, P, Fekete, S, Voros, V, Vitrai, J. Sexual dysfunction among patients treated with antidepressants – a Hungarian retrospective study. Eur Psychiat 2003; 18(8): 412–414.Google Scholar
6.Taylor, D, Paton, C, Kerwin, R. The Maudsley Prescribing Guidelines (9th Ed.) United Kingdom: Informa Healthcare, 2007.CrossRefGoogle Scholar
7.Ferguson, J. SSRI Antidepressant Medications: Adverse Effects and Tolerability. J Clin Psychiat 2001; 3(1): 22–27.Google ScholarPubMed
8.Nurnberg, G, Hensley, P, Heiman, J, Croft, H, Debattista, C, Paine, S. Sildenafil treatment of women with anti-depressant associated sexual dysfunction: A randomized controlled trial. JAMA 2008; 300(4): 395–404.Google Scholar
9.Yang, C, Jiang, X. (2009) Clinical autonomic neurophysiology and the male sexual response: an overview. J Sexual Med 2009; 3: 221–228.CrossRefGoogle Scholar
10.Meston, C. Sympathetic nervous system activity and female sexual arousal. Am J Cardiol 2000; 2(1): 30–34.CrossRefGoogle Scholar
11.Brill, M. Antidepressants and sexual dysfunction. Sexuality, Reproduction and Menopause 2004; 2(1): 35–40.CrossRefGoogle Scholar
12.Settle, E. Antidepressant drugs: disturbing and potentially dangerous adverse effects. J Clin Psychiat 1998; 59(16): 25–30.Google ScholarPubMed
13.Balon, R, Segraves, R. Survey of treatments practices for sexual dysfunction(s) associated with ant-depressants. J Sex Marital Ther 2008; 34(4): 353–365.CrossRefGoogle Scholar
14.Nurnberg, G, Hensley, P, Gelenberg, A, Fava, M, Lauriello, J, Paine, S. Treatment of antidepressant-associated sexual dysfunction with sildenafil: A randomized controlled trial. JAMA 2003; 289: 56–64.CrossRefGoogle ScholarPubMed
15.Nurnberg, G, Seidman, S, Gelenberg, A, Fava, M, Rosen, R, Shabsigh, R. Depression, antidepressant therapies, and erectile dysfunction: clinical. Of sildenafil citrate (Viagra) in treated and untreated patients with Depression. Urology 2002; 60(2): 58–66.CrossRefGoogle ScholarPubMed