Hostname: page-component-78c5997874-g7gxr Total loading time: 0 Render date: 2024-11-13T05:57:14.119Z Has data issue: false hasContentIssue false
  • English
  • Français

SSRIs, aggression and suicide – a cause for concern or the result of media hype?

Published online by Cambridge University Press:  13 June 2014

Brian E Leonard
Brian E Leonard*
Affiliation:
National University of Ireland, Galway, Ireland; Brain Research Institute, University of Maastricht, The Netherlands
Rights & Permissions [Opens in a new window]

Abstract

An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Editorial
Information
Irish Journal of Psychological Medicine , Volume 21 , Issue 2 , June 2004 , pp. 40 - 42
Copyright
Copyright © Cambridge University Press 2004

References

1.Creaney, W, Murray, I, Healy, D. Antidepressant induced suicidal ideation. Hum Psychopharmacol 1991; 6:329–32.CrossRefGoogle Scholar
2.Healy, DA. A failure to warn. Editorial. Int J Risk & Safety in Med, 1999; 12:151–6.Google Scholar
3.Beasley, CM, Dornseif, BE, Bosomworth, JCet al.Fluoxetine and suicide: a metaanalysis of controlled trials of treatment for depression. BMJ 1991; 303: 685–92.CrossRefGoogle ScholarPubMed
4.Healy, D, Creaney, W. Antidepressant induced suicidal ideation. Brit Med J 1991; 303:1058–9.CrossRefGoogle Scholar
5.Healy, D. Let them eat Prozac. James Lorimer & Co. Toronto, 2003; 269Google Scholar
6.Rothschild, A T, Locke, C A. Re-exposure to fluoxetine after serious suicidal attempts by three patients: the role of akathisia. J Clin Psychiat 1991; 52:491–493.Google Scholar
7.Teicher, M H, Glod, C, Cole, J O. Emergence of intense suicidal preoccupation during fluoxetine treatment. Am J Psychiat 1990; 147: 207–210.Google ScholarPubMed
8.Ayd, F. A survey of drug induced extrapyramidal reactions. JAMA 1961; 175:1054–60.CrossRefGoogle ScholarPubMed
9.Lader, M. Psychiatric Disorders In: Avery's Drug Treatment, 4th Edition Eds. Speight, TM, Holford, NHG. Adis International Ltd. Auckland, New Zealand. 1987;1046–1047.Google Scholar
10.Wojcik, J D, Gelenberg, A J, LaBrie, R A & Mieske, M. Prevalence of tardive dyskinesia in an outpatient population. Compr Psychiat 1980; 21: 370–379.CrossRefGoogle Scholar
11.Patterson, JF. Amoxapine-induced chorea. South Med J 1983; 76:1077.iCrossRefGoogle ScholarPubMed
12.Joseph, A B, Wrobiewski, B A. Paradoxical akathisia caused by clonazepam, clorazepate and lorazepam in patients with traumatic encephalopathy and seizure disorders: a subtype of benzodiazepine-induced disinhibition. Behav Neurol 1993; 6: 221–3.CrossRefGoogle ScholarPubMed
13.Riley, D E, Lang, A E. The spectrum of levodopa-related fluctuations in Parkinson's disease. Neurology, 1993; 43:1459–1464.CrossRefGoogle ScholarPubMed
14.Gerber, P E, Lynd, L D. Selective serotonin reuptake inhibitor induced movement disorders. Ann Pharmacotherap. 1998; 32: 692–8.CrossRefGoogle ScholarPubMed
15.King, A, Riddle, M A, Chappell, P Bet al.Emergence of self destructive phenomena in children and adolescents during fluoxetine treatment. J Amer Acad Child Adult Psychiat 1991; 30: 176.Google ScholarPubMed
16Hall, W D, Mant, A, Mitchell, PBet al.Association between antidepressant prescribing and suicide in Australia, 1991–2000: trend analysis. BMJ 2003; 326: 1008–1013.CrossRefGoogle ScholarPubMed
17.Jick, S S, Dean, A D, Jick, H. Antidepressants and suicide. BMJ 1995; 310: 215–8.CrossRefGoogle ScholarPubMed
18.Tollefson, G D, Fawcett, J, Winokur, Get al.Evaluation of suicidality during pharmacologic treatment of mood and nonmood disorders. Ann Clin Psychiat 1993; 5: 209–224.CrossRefGoogle ScholarPubMed
19.Tollefson, GD, Rampey, A H, Beasley, C Met al.Absence of a relationship between adverse events and suicidality during pharmacotherapy for depression. J Clin Psychopharmacol 1994; 14:163–169.CrossRefGoogle ScholarPubMed
20.Warshaw, MG, Keller, MB. The relationship between fluoxetine use and suicidal behaviour in 654 subjects with anxiety disorders. J Clin Psychiat 1996; 57:158–166Google ScholarPubMed
21.Leon, A C, Keller, M B, Warshaw, M Get al.Prospective study of fluoxetine treatment and suicidal behaviour in affectively ill subjects. Am J Psychiat 1999; 156:195–201.CrossRefGoogle ScholarPubMed
22.Mackay, FJ, Dunn, NR, Wilton, LVet al.A comparison of fluvoxamine, fluoxetine, sertraline and paroxetine examined by observational cohort studies. Pharmacoepidemiol Drug Safety 1997; 6: 235–246.3.0.CO;2-3>CrossRefGoogle ScholarPubMed
23.Edwards, JG. Drug choice in depression. Selective serotonin reuptake inhibitors or tricyclic antidepressants? CNS Drugs 1995; 4: 141–159.CrossRefGoogle Scholar
24.Kasper, S, Schindler, S, Neumeister, A. Risk of suicide in depression and its implications for psychopharmacological treatment. Int Clin Psychopharmacol 1996; 11: 71–79.Google ScholarPubMed
25.Committee on Safety of Medicines. Current problems in pharmacovigilance – Selective Serotonin Reuptake Inhibitors (SSRIs) 2000; 26: 11–12.Google Scholar
26. Food and Drug Administration, Review of antidepressants: Psycho Drugs Advisory Committee Report. September, 1991.Google Scholar
27.Walsh, M-T, Dinan, TG, Selective serotonin reuptake inhibitors and violence: a review of the available evidence. Acta Psychiat Scand 2001; 104: 84–91.CrossRefGoogle ScholarPubMed
28.Nyth, A L, Gottfries, C G. The clinical efficacy of Citalopram in the treatment of emotional disturbance in dementia disorder. Br J Psychiat 1990; 51(7): 894–901.CrossRefGoogle Scholar
29.Pinner, E, Rich, CL. Effects of trazodone on aggressive behaviour in 7 patients with organic mental disorders. Am J Psychiat 1988; 145:1295–1296.Google Scholar
30.Stanley, B, Molcho, A, Stanley, Met al.Association of aggressive behaviour with altered serotoninergic function in patients who are not suicidal. Am J Psychiat 2000; 157:609–614.CrossRefGoogle Scholar
31.Rosenbaum, JF. Clinical trials by media: the Prozac story. In (Ed. Schwartz, HI.) Psychotropic practice under fire. The influence of the Government, the media and special interests on somatic therapies. American Psychiatric Association Press, Washington, DC 1994; 3–27.Google Scholar
32.Khan, A, Brown, WA. Suicide rates in clinical trials of SSRIs, other antidepresants and placebo:analysis of FDA reports. Am J Psychiat 2003; 160: 790–792.CrossRefGoogle Scholar
33.Hall, WD. Mant, A. Mitchell, PB. Rendle, VA, Hickie, IB. McManus, P. Association between antidepressant prescribing and suicide in Australia, 1991–2000: trend analysis. BMJ 2003; 326: 1008–17.CrossRefGoogle ScholarPubMed
34.Carlten, A. Waern, M. Ekedahl, A, Ranstram, J. Antidepressant medication and suicide in Sweden. Pharmacoepidemiol. Drug Safety 2001; 10: 525–530.Google Scholar
35.Rihmer, Z. Can better recognition and treatment of depression reduce suicide rates? A brief review. Eur Psychiatry 2001; 16: 406–409.CrossRefGoogle ScholarPubMed