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The response of plasma minerals, free fatty acids and glucose to adrenaline and cortisol infusion in sheep

Published online by Cambridge University Press:  27 March 2009

Sarah C. Bolton
Affiliation:
Department of Agricultural Biochemistry and Nutrition, The University, Newcastle upon Tyne, NE1 7RU
T. E. C. Weekes
Affiliation:
Department of Agricultural Biochemistry and Nutrition, The University, Newcastle upon Tyne, NE1 7RU

Summary

Adrenaline was infused at three rates, 40, 15 or 3 μ/kg/h, in normal sheep and in sheep rendered hypercortisolaemic by infusion of cortisol at 150 μg/kg/h. In both normal and hypercortisolaemic animals, plasma concentrations of glucose and free fatty acids were increased by adrenaline treatment; plasma phosphate decreased with all treatments; plasma magnesium and potassium decreased on infusion of adrenaline at 40 or 15, but not at 3 μg/kg/h; plasma calcium decreased only on infusion of adrenaline in hypercortisolaemic animals, and plasma sodium concentration was unaffected by treatment.

Induction of a degree of lipolysis likely to occur in the field was not associated with a marked decrease in plasma magnesium.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1986

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