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The development of some digestive enzymes in the intestines of pigs reared artificially

Published online by Cambridge University Press:  27 March 2009

Rosa M. Campbell ,
Helen Brough  and
B. F. Fell
Rosa M. Campbell
Affiliation:
Rowett Research Institute, Bucksburn, Aberdeen
Helen Brough
Affiliation:
Rowett Research Institute, Bucksburn, Aberdeen
B. F. Fell
Affiliation:
Rowett Research Institute, Bucksburn, Aberdeen
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Summary

A comparison was made of the development of acid and alkaline phosphatase, invertase, lactase and leucine aminopeptidase specific activities in the small intestines of two groups of neonatal pigs. The groups consisted of two litters of suckling pigs and two litters of pigs that were delivered by hysterectomy and reared in incubators on a diet based on cow's milk. In the unsuckled pigs there was retardation of the development of invertase and leucine aminopeptidase. The unsuckled animals grew slowly and were affected by diarrhoea, and it is possible that enteric disease may have affected the development of the brush border of the intestinal epithelial cells, or enzymes specifically associated with the microvilli.

Type
Research Article
Information
The Journal of Agricultural Science , Volume 76 , Issue 3 , June 1971 , pp. 531 - 538
Copyright
Copyright © Cambridge University Press 1971

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References

REFERENCES

Alexander, V. A. W. (1969). Studies on the nutrition of the neonatal pig. Ph.D. Thesis, University of Edinburgh.Google Scholar
Bergmeyer, H. U. & Bernt, E. (1963). D-Glucose determination with glucose oxidase and peroxidase. In Methods of Enzymatic Analysis (ed. Bergmeyer, H. U.), pp. 123–30. New York: Academic Press.Google Scholar
Boehringer, C. F. & Sons, (1968). Biochemica Catalogue, 1st edn.Mannheim, Germany.Google Scholar
Brown, H. O., Levine, M. L. & Lipkin, M. (1963). Inhibition of intestinal epithelial cell renewal and migration induced by starvation. Am. J. Physiol. 205, 868–72.Google Scholar
Eichholz, A. (1967). Structural and functional organization of the brush border of intestinal epithelial cells. III. Enzymatic activities and chemical composition of various fractions of Tris-disrupted brush borders. Biochim. biophys. Acta 135, 475–82.Google Scholar
Hübscher, G., West, G. R. & Brindley, D. N. (1965). Studies on the fractionation of mucosal homogenates from the small intestine. Biockem. J. 97, 629–42.Google ScholarPubMed
Kenworthy, R. & Allen, W. D. (1966). Influence of diet and bacteria on small intestinal morphology, with special reference to early weaning and Escherichia coli. Studies with germ-free and gnotobiotic pigs. J. comp. Path. 76, 291–6.Google Scholar
Lecce, J. G. (1965–1966). Absorption of macromolecules by neonatal intestine. Biologia Neonat. 9, 50–61.CrossRefGoogle ScholarPubMed
Lecce, J. G., Matrone, G. & Morgan, D. O. (1961). Porcine neonatal nutrition: Absorption of unaltered nonporcine proteins and polyvinylpyrrolidone from the gut of piglets and the subsequent effect on the maturation of the serum profile. J. Nutr. 73, 158–66.Google Scholar
McCance, R. A. & Widdowson, E. M. (1964). Protein metabolism and requirements in the new born. In Mammalian Protein Metabolism, vol. II (eds. Munro, H. N. and Allison, J. B.), pp. 225–45. London: Academic Press.CrossRefGoogle Scholar
Miller, D. & Crane, R. K. (1961). The digestive function of the epithelium of the small intestine. II. Localization of disaccharide hydrolysis in the isolated brush border portion of intestinal epithelial cells. Biochim. biophys. Acta 52, 293–9.Google Scholar
Munro, H. N. & Goldberg, D. M. (1964). The effect of protein intake on the protein and nucleic acid metabolism of the intestinal mucosal cell. In The Role of the Gastrointestinal Tract in Protein Metabolism. C.I.O.M.S. Symposium (ed. Munro, H. N.), pp. 189–96. Oxford: Blackwell.Google Scholar
Porteous, J. W. (1969). Isolation of brush borders (microvilli) from the epithelial cells of mammalian intestine. In Subcellular Components (eds. Birnie, G. D. and Fox, S. M.), pp. 57–81. London: Butterworths.Google Scholar
Porteous, J. W. & Clark, B. (1965). The isolation and characterization of subcellular components of the epithelial cells of rabbit small intestine. Biochem. J. 96, 159–71.Google Scholar
Rhodes, J. B., Eichholz, A. & Crane, R. K. (1967). Studies on the organization of the brush border in intestinal epithelial cells. IV. Aminopeptidase activity in microvillus membranes of hamster intestinal brush borders. Biochim. biophys. Acta 135, 959–65.Google Scholar
Smith, H. W. & Jones, J. E. T. (1963). Observations on the alimentary tract and its bacterial flora in healthy and diseased pigs. J. Path. Bact. 86, 387–412.Google Scholar
Sun, T. P. (1927). Histophysiological study of the epithelial changes in the small intestine of the albino mouse after starvation and refeeding. Anat. Rec. 34, 341–9.CrossRefGoogle Scholar