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Effect of royal jelly on milk composition and blood biochemical parameters in lactating ewes

Published online by Cambridge University Press:  27 May 2019

Mahmoud S. El-Tarabany Open the ORCID record for Mahmoud S. El-Tarabany [Opens in a new window] ,
Akram A. El-Tarabany ,
Mostafa A. Atta ,
Omar A. Ahmed-Farid  and
Mohamed M. Mostafa
Mahmoud S. El-Tarabany*
Affiliation:
Department of Animal Wealth Development, Faculty of Veterinary Medicine, Zagazig University, Sharkia, Egypt
Akram A. El-Tarabany
Affiliation:
Biological Applications Department, Radioisotopes Applications Division, NRC, Atomic Energy Authority, Inshas, Cairo, Egypt
Mostafa A. Atta
Affiliation:
Biological Applications Department, Radioisotopes Applications Division, NRC, Atomic Energy Authority, Inshas, Cairo, Egypt
Omar A. Ahmed-Farid
Affiliation:
Physiology department, National Organization for Drug Control and Research (NODCAR), Cairo, Egypt
Mohamed M. Mostafa
Affiliation:
Biological Applications Department, Radioisotopes Applications Division, NRC, Atomic Energy Authority, Inshas, Cairo, Egypt
*
Author for correspondence: Mahmoud S. El-Tarabany, E-mail: mahmoudtarabany2887@yahoo.com
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Abstract

Use of antibiotics as feed additives has been reduced to avoid the hazard of drug residues, and consequently, the search for alternative natural additives has developed. Thus, the aim was to evaluate the influence of royal jelly (RJ) supplementation on milk composition, blood biochemical and antioxidant parameters of lactating ewes. Thirty-six Ossimi ewes were divided randomly into two groups (18 animals each). For a period of 4 weeks, the control group (CON) was fed a basal diet only, while the other group was fed the basal diet and supplemented with a single bolus of RJ (1000 mg/head). The RJ-supplemented ewes produced significantly higher milk protein, fat and total solids than the CON group. The RJ group had a significantly higher red blood cell count, haemoglobin content, haematocrit value and total leucocyte counts, but lower neutrophil to lymphocyte ratio when compared with the control treatment. The RJ group showed significantly higher concentrations of total antioxidant capacity, superoxide dismutase activity and glutathione in the serum compared with the control treatment. In conclusion, RJ supplements can improve the nutritive value of milk fat and the serum antioxidant activities in lactating ewes.

Keywords

Antioxidant activitylactating ewesmilk compositionroyal jelly
Type
Animal Research Paper
Information
The Journal of Agricultural Science , Volume 157 , Issue 2 , March 2019 , pp. 176 - 181
Copyright
Copyright © Cambridge University Press 2019 

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References

Aebi, H (1984) Catalase in vitro. Methods in Enzymology 105, 121–126.Google Scholar
Aguiar, SC, Cottica, SM, Boeing, JS, Samensari, RB, Santos, GT, Visentainer, JV and Zeoula, LM (2014) Effect of feeding phenolic compounds from propolis extracts to dairy cows on milk production, milk fatty acid composition, and the antioxidant capacity of milk. Animal Feed Science and Technology 193, 148–154.Google Scholar
Akaike, H (1973) Information theory and an extension of the maximum likelihood principle. In Petrov, BN and Csaki, F (eds), Proceedings of the 2nd International Symposium on Information Theory. Budapest, Hungary: Akademiai Kiado, pp. 267–281.Google Scholar
AOAC (1990) Official Methods of Analysis, 15th Edn. Arlington, Virginia, USA: AOAC.Google Scholar
Benzie, IF and Strain, JJ (1996) The ferric reducing ability of plasma [FRAP] as a measure of “antioxidant power”: the FRAP assay. Analytical Biochemistry 239, 70–76.Google Scholar
Brown, K, Uwiera, RRE, Kalmokoff, ML, Brooks, SPJ and Inglis, GD (2017) Antimicrobial growth promoter use in livestock: a requirement to understand their modes of action to develop effective alternatives. International Journal of Antimicrobial Agents 49, 12–24.Google Scholar
Cardenia, V, Rodriguez-Estrada, MT, Baldacci, E, Savioli, S and Lercker, G (2012) Analysis of cholesterol oxidation products by fast gas chromatography/mass spectrometry. Journal of Separation Science 35, 424–430.Google Scholar
Choi, YH, Hong, YJ, Ahn, Y, Park, IH and Jeong, MH (2014) Relationship between neutrophil-to-lymphocyte ratio and plaque components in patients with coronary artery disease: virtual histology intravascular ultrasound analysis. Journal of Korean Medical Science 29, 950–956.Google Scholar
de Bie, L, Berger, YM and Thomas, DL (2000) The effect of three times a day milking at the beginning of lactation on the milk production of East Friesian crossbred ewes. In Thomas, DL and Porter, S (eds), Proceedings of the 6th Great Lakes Dairy Sheep Symposium: November 2-4, 2000, Guelph, Ontario, Canada. Shelburne, Ontario, Canada: Ontario Dairy Sheep Association, pp. 1–9.Google Scholar
El-Nekeety, AA, El-Kholy, W, Abbas, NF, Ebaid, A, Amra, HA and Abdel-Wahhab, MA (2007) Efficacy of royal jelly against the oxidative stress of fumonisin in rats. Toxicon 50, 256–269.Google Scholar
Hattori, N, Nomoto, H, Fukumitsu, H, Mishima, S and Furukawa, S (2007) Royal jelly and its unique fatty acid, 10-hydroxy-trans-2-decenoic acid, promote neurogenesis by neural stem/progenitor cells in vitro. Biomedical Research 28, 261–266.Google Scholar
Husein, MQ and Kridli, RT (2002) Reproductive responses following royal jelly treatment administered orally or intramuscularly into progesterone-treated Awassi ewes. Animal Reproduction Science 74, 45–53.Google Scholar
Inoue, S, Koya-Miyata, S, Ushio, S, Iwaki, K, Ikeda, M and Kurimoto, M (2003) Royal jelly prolongs the life span of C3H/HeJ mice; correlation with reduced DNA damage. Experimental Gerontology 38, 965–969.Google Scholar
Izuta, H, Chikaraishi, Y, Shimazawa, M, Mishima, S and Hara, H (2009) 10-Hydroxy-2-decenoic acid, a major fatty acid from royal jelly, inhibits VEGF-induced angiogenesis in human umbilical vein endothelial cells. Evidence-Based Complementary and Alternative Medicine 6, 489–494.Google Scholar
Jayatilleke, E and Shaw, S (1993) A high performance liquid chromatographic assay for reduced and oxidized glutathione in biological samples. Analytical Biochemistry 214, 452–457.Google Scholar
Kalafova, A, Hascik, P, Kacaniova, M, Petruska, P and Capcarova, M (2015) The effect of propolis on biochemical parameters and antioxidant status of the blood of broiler chickens. Journal of Apicultural Research 54, 173–178.Google Scholar
Kanbur, M, Eraslan, G, Beyaz, L, Silici, S, Liman, BC, Altinordulu, S and Atasever, A (2009) The effects of royal jelly on liver damage induced by paracetamol in mice. Experimental and Toxicologic Pathology 61, 123–132.Google Scholar
Karatas, F, Karatepe, M and Baysar, A (2002) Determination of free malondialdehyde in human serum by high performance liquid chromatography. Analytical Biochemistry 311, 76–79.Google Scholar
Koya-Miyata, S, Arai, N, Mizote, A, Taniguchi, Y, Ushio, S, Iwaki, K and Fukuda, S (2009) Propolis prevents diet-induced hyperlipidemia and mitigates weight gain in diet-induced obesity in mice. Biological and Pharmaceutical Bulletin 32, 2022–2028.Google Scholar
Lindmark-Mansson, H and Akesson, B (2000) Antioxidative factors in milk. British Journal of Nutrition 84(suppl. 1), S103–S110.Google Scholar
Liu, JR, Yang, YC, Shi, LS and Peng, CC (2008) Antioxidant properties of royal jelly associated with larval age and time of harvest. Journal of Agricultural and Food Chemistry 56, 11447–11452.Google Scholar
Lock, AL and Shingfield, KJ (2004) Optimising milk composition. In Kebreab, E, Mills, J and Beever, DE (eds), Dairying: Using Science to Meet Consumers' Needs. British Society of Animal Science, Occasional Publication 29. Nottingham, UK: Nottingham University Press, pp. 107–188.Google Scholar
Morsy, AS, Abdalla, AL, Soltan, YA, Sallam, SMA, El-Azrak, KEM, Louvandini, H and Alencar, SM (2013) Effect of Brazilian red propolis administration on haematological, biochemical variables and parasitic response of Santa Inês ewes during and after flushing period. Tropical Animal Health and Production 45, 1609–1618.Google Scholar
Morsy, AS, Soltan, YA, Sallam, SMA, Alencar, SM and Abdalla, AL (2016) Impact of Brazilian red Propolis extract on blood metabolites, milk production, and lamb performance of Santa Inês ewes. Tropical Animal Health and Production 48, 1043–1050.Google Scholar
Nagai, T and Inoue, R (2004) Preparation and the functional properties of water extract and alkaline extract of royal jelly. Food Chemistry 84, 181–186.Google Scholar
Nandi, A and Chatterjee, IB (1988) Assay of superoxide dismutase activity in animal tissues. Journal of Biosciences 13, 305–315.Google Scholar
National Research Council (NRC) (2007) Nutrient Requirements of Small Ruminants. Washington, DC, USA: National Academy of Sciences.Google Scholar
Okamoto, I, Taniguchi, Y, Kunikata, T, Kohno, K, Iwaki, K, Ikeda, M and Kurimoto, M (2003) Major royal jelly protein 3 modulates immune responses in vitro and in vivo. Life Science 73, 2029–2045.Google Scholar
Orsolić, N and Basić, I (2005) Antitumor, hematostimulative and radioprotective action of water-soluble derivative of propolis (WSDP). Biomedicine & Pharmacotherapy 59, 561–570.Google Scholar
Pan, Y, Xu, J, Chen, C, Chen, F, Jin, P, Zhu, K, Hu, CW, You, M, Chen, M and Hu, F (2018) Royal jelly reduces cholesterol levels, ameliorates Aβ pathology and enhances neuronal metabolic activities in a rabbit model of Alzheimer's disease. Frontiers in Aging Neuroscience 10, 1–14, article no. 50. doi: 10.3389/fnagi.2018.00050.Google Scholar
Pasupuleti, VR, Sammugam, L, Ramesh, N and Gan, SH (2017) Honey, propolis, and royal jelly: a comprehensive review of their biological actions and health benefits. Oxidative Medicine and Cellular Longevity 2017, 1–21, article no. 1259510. doi: doi.org/10.1155/2017/1259510.Google Scholar
Ramadan, MF and Al-Ghamdi, A (2012) Bioactive compounds and health-promoting properties of royal jelly: a review. Journal of Functional Foods 4, 39–52.Google Scholar
Santos, NW, Yoshimura, EH, Machado, E, Matumoto-Pintro, PT, Montanher, PF, Visentainer, JV, dos Santos, GT and Zeoula, L (2016) Antioxidant effects of a propolis extract and vitamin E in blood and milk of dairy cows fed diet containing flaxseed oil. Livestock Science 191, 132–138.Google Scholar
SAS (2003) SAS/STAT User's Guide. Cary, NC, USA: SAS Institute Inc.Google Scholar
Seven, I, Aksu, T and Tatli Seven, P (2012) The effects of propolis and vitamin C supplemented feed on performance, nutrient utilization and carcass characteristics in broilers exposed to lead. Livestock Science 148, 10–15.Google Scholar
Tamura, S, Kono, T, Harada, C, Yamaguchi, K and Moriyama, T (2009) Estimation and characterisation of major royal jelly proteins obtained from the honeybee Apis merifera. Food Chemistry 114, 1491–1497.Google Scholar
Torreão, JNDC, Rocha, AM, Marques, CAT, Bezerra, LR, Gottardi, FP, Araújo, MJD, Souza Júnior, ELD and Oliveira, RL (2014) Concentrate supplementation during pregnancy and lactation of ewes affects the growth rate of lambs from a variety of crosses. Revista Brasileira de Zootecnia 43, 544–550.Google Scholar
Vucevic, D, Melliou, E, Vasilijic, S, Gasic, S, Ivanovski, P, Chinou, I and Colic, M (2007) Fatty acids isolated from royal jelly modulate dendritic cell-mediated immune response in vitro. International Immunopharmacology 7, 1211–1220.Google Scholar
Zhao, X, Wang, J, Yang, Y, Bu, D, Cui, H, Sun, Y, Xu, X and Zhou, L (2013) Effects of different fat mixtures on milk fatty acid composition and oxidative stability of milk fat. Animal Feed Science and Technology 185, 35–42.Google Scholar