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The BMI–adiposity conundrum in South Asian populations: need for further research

Published online by Cambridge University Press:  04 April 2019

Nitin Kapoor*
Affiliation:
Department of Endocrinology, Diabetes and Metabolism, Christian Medical College & Hospital, Vellore, Tamil Nadu, India Melbourne School of Population and Global Health, Faculty of Medicine, Dentistry and Health Science, University of Melbourne, Australia
John Furler
Affiliation:
Department of General Practice, Faculty of Medicine, Dentistry and Health Science, University of Melbourne, Australia
Thomas V. Paul
Affiliation:
Department of Endocrinology, Diabetes and Metabolism, Christian Medical College & Hospital, Vellore, Tamil Nadu, India
Nihal Thomas
Affiliation:
Department of Endocrinology, Diabetes and Metabolism, Christian Medical College & Hospital, Vellore, Tamil Nadu, India
Brian Oldenburg
Affiliation:
Melbourne School of Population and Global Health, Faculty of Medicine, Dentistry and Health Science, University of Melbourne, Australia
*
*Corresponding author. Email: nitin.kapoor@cmcvellore.ac.in

Abstract

High body fat in apparently lean individuals is a commonly described phenotype in individuals of Asian descent, but very limited consolidated scientific literature is available on this topic. This phenotype is known as ‘normal-weight obesity’ and may explain the large disparity between the prevalence of obesity (as measured by BMI) and diabetes that occurs in these individuals. Routine use of obesity indicators that best predict body fat content would help to identify these individuals in clinical practice. In this debate, we would like to highlight that even though fat and BMI have a good correlation, as suggested by Kryst et al. (2019), clinicians, public health researchers and policymakers should consider the use of these indicators in conjunction with each other rather than individually. Future research is needed on pathogenic mechanisms, diagnostic modalities and therapeutic options in these individuals which will help to further characterize and manage these patients appropriately.

Type
Debate
Copyright
© Cambridge University Press, 2019 

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