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Incidence of ovulatory cycles in women approaching the menopause

Published online by Cambridge University Press:  31 July 2008

Mary G. Metcalf
Mary G. Metcalf
Affiliation:
medical Unit, Princess Margart Hospital, Chirstchruch2, New Zealand.
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Summary

Urine was collected at weekly intervals at weekly intervals for three or more months from 139 menstruant women aged 40–55 years. Menstrual cycles were classed as ovulatory if the 24-hr pregnanediol output was > 5 μmol on a single occasion, or if the total excreted on 2 days 1 week apart was > 7 μmol. Of the 81 women who reported no change in menstrual frequency, 95% ovulated in every cycle. Only 34% of the 53 with a recent history of oligomenorrhoea ovulated without fail. Ovalation occurred in 93% of all 21–35-day menstrual cycles, in 55% of 36–50-day cycles, in 40% of 51–75-day cycles and in 17% of those lasting > 76 days. Pregnanediol increases suggestive of ovulation and followed by menstruation were observed on 31 occasions after amenorrhoea of from 2 to 6 months' duration.

Type
Research Article
Information
Journal of Biosocial Science , Volume 11 , Issue 1 , January 1979 , pp. 39 - 48
Copyright
Copyright © 1979, Cambridge University Press

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References

Bailey, J. & Marshall, J. (1970) The relationship of the post-ovulatory phase of the menstrual cycle to the total cycle length. J. biosoc. Sci. 2, 123.Google Scholar
Burch, P.R.J. & Gunz, F.W. (1967) The distribution of the menopausal age in New Zealand. An exploratory study. N.Z. med. J. 66, 6.Google ScholarPubMed
Chasson, A.L., Grady, H.J. & Stanley, M.A. (1961) The determination of creatinine by means of automatic chemical analysis. Am. J. clin. Path. 35, 83.Google Scholar
Costoff, A. & Mahesh, V.B. (1975) Primordial follicles with normal oocytes in the ovaries of postmenopausal women. J. Am. Geriat. Soc. 23, 193.CrossRefGoogle ScholarPubMed
Doring, G.K. (1969) The incidence of anovular cycles in women. J. Reprod. Fert. Suppl. 6, 77.Google Scholar
Mckinlay, S., Jefferys, M. & Thompson, B. (1972) An investigation of the age at menopause. J. biosoc. Sci. 4, 161.CrossRefGoogle ScholarPubMed
Metcalf, M.G. (1973) Rapid gas chromatographic assay for progesterone metaboites in urine. Clin. Biochem. 6, 307.Google Scholar
Metcalf, M.G. (1976) Are 24-hour urine collections necessary for the measurement of steroid excretion rates?. N.Z. med. J. 84, 150.Google ScholarPubMed
Odell, W.D., Parlow, A.F., Cargille, C.M. & Ross, G.T. (1968) Radioimmunoassay for follicle stimulating hormone: physiological studies. J. clin. Invest. 47, 2551.Google Scholar
Sherman, B.M., West, J.H. & Korenman, S.G. (1976) The menopausal transition: analysis of LH, FSH, estradiol and progesterone concentrations during menstrual cycles of older women. J. clin. Endocr. Metab. 42, 629.Google Scholar
Treloar, A.E., Boynton, R.E., Benn, B.G. & Brown, B.W. (1967) Variation of the human menstrual cycle through reproductive life. Int. J. Fert. 12, 77.Google ScholarPubMed