Hostname: page-component-cd9895bd7-jn8rn Total loading time: 0 Render date: 2024-12-26T06:55:47.978Z Has data issue: false hasContentIssue false
  • English
  • Français

Effect of trypsin on bovine lactoferrin and interaction between the fragments under different conditions

Published online by Cambridge University Press:  01 June 2009

Luis Mata ,
Helena Castillo ,
Lourdes Sánchez ,
Pilar Puyol  and
Miguel Calvo
Luis Mata
Affiliation:
Tecnologíay Bioquímica de los Alimentos, Facultad de Veterinaria, Miguel Servet 177, 50013 Zaragoza, España
Helena Castillo
Affiliation:
Tecnologíay Bioquímica de los Alimentos, Facultad de Veterinaria, Miguel Servet 177, 50013 Zaragoza, España
Lourdes Sánchez
Affiliation:
Tecnologíay Bioquímica de los Alimentos, Facultad de Veterinaria, Miguel Servet 177, 50013 Zaragoza, España
Pilar Puyol
Affiliation:
Tecnologíay Bioquímica de los Alimentos, Facultad de Veterinaria, Miguel Servet 177, 50013 Zaragoza, España
Miguel Calvo*
Affiliation:
Tecnologíay Bioquímica de los Alimentos, Facultad de Veterinaria, Miguel Servet 177, 50013 Zaragoza, España
*
* For correspondence.
Get access Rights & Permissions [Opens in a new window]

Abstract

An abstract is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Short Communications
Information
Journal of Dairy Research , Volume 61 , Issue 3 , August 1994 , pp. 427 - 432
Copyright
Copyright © Proprietors of Journal of Dairy Research 1994

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Bellamy, W., Takase, M., Yamauchi, K., Wakabayashi, H., Kawase, K. & Tomita, M. 1992 Identification of the bactericidal domain of lactoferrin. Biochimica et Biophysica Acta 1121 130–136CrossRefGoogle ScholarPubMed
Bennett, R. M., Bagby, G. C. & Davis, J. 1981 Calcium-dependent polymerization of lactofurrin. Biochemical and Biophysical Research Communications 101 88–95CrossRefGoogle Scholar
Brines, R. D. & Brock, J. H. 1983 The effect of trypsin and chymotrypsin on the in vitro antimicrobial and iron-binding properties of lactoferrin in human milk and bovine colostrum. Unusual resistance of human apolactoferrin to proteolytic digestion. Biochimica et Biophysica Acta 759 229–235CrossRefGoogle ScholarPubMed
Brock, J. H., Arzabe, F., Lampreave, F. & Piñeiro, A. 1976 The effect of trypsin on bovine transferrin and lactoferrin. Biochimica et Biophysica Acta 446 214–225CrossRefGoogle ScholarPubMed
Butler, J. E. 1973 The occurrence of immunoglobulin fragments, two types of lactoferrin and a lactoferrin-IgG2 complex in bovine colostral and milk whey. Biochimica et Biophysica Acta 295 341–351CrossRefGoogle Scholar
Jorieux, S., Mazurier, J., Montreuil, J. & Spik, G. 1985 Characterization of lactotransferrin complexes in human milk. Protides of the Biological Fluids 32 115–118CrossRefGoogle Scholar
Lampreave, F., Piñeiro, A., Brock, J. H., Castillo, H., Sánchez, L. & Calvo, M. 1990 Interaction of bovine lactoferrin with other proteins of milk whey. International Journal of Biological Macromolecules 12 2–5CrossRefGoogle ScholarPubMed
Legrand, D., Mazurier, J., Aubert, J. P., Loucheux-Lefebvre, M. H., Montreuil, J. & Spik, G. 1986 Evidence for interactions between the 30 kDa N- and 50 kDa C-terminal tryptic fragments of human lactotransferrin. Biochemical Journal 236 839–844CrossRefGoogle ScholarPubMed
Legrand, D., Mazurier, J., Colavizza, D., Montreuil, J. & Spik, G. 1990 Properties of the iron-binding site of the N-terminal lobe of human and bovine lactotransferrins. Importance of the glycan moiety and of the non-covalent interactions between the N- and C-terminal lobes in the stability of the iron-binding site. Biochemical Journal 266 575–581Google Scholar
Line, W. F., Sly, D. A. & Bezkorovainy, A. 1976 Limited cleavage of human lactoferrin with pepsin. International Journal of Biochemistry 7 203–208CrossRefGoogle Scholar
Sánchez, L., Aranda, P., Pérez, M.-D. & Calvo, M. 1988 Concentration of lactoferrin and transferrin throughout lactation in cow's colostrum and milk. Biological Chemistry Hoppe-Seyler 369 1005–1008CrossRefGoogle ScholarPubMed
Sánchez, L., Calvo, M. & Brock, J. H. 1992 Biological role of lactoferrin. Archives of Disease in Childhood 67 657–661CrossRefGoogle ScholarPubMed
Tomita, M., Bellamy, W., Takase, M., Yamauchi, K., Wakabayashi, H. & Kawase, K. 1991 Potent antibacterial peptides generated by pepsin digestion of bovine lactoferrin. Journal of Dairy Science 74 4137–4142CrossRefGoogle ScholarPubMed
Watanabe, T., Nagura, H., Watanabe, K. & Brown, W. R. 1984 The binding of human milk lactoferrin to immunoglobulin A. FBBS Letters 168 203–207CrossRefGoogle ScholarPubMed