Molecular characterization of the goat CSN1S101 allele

Gianfranco Cosenza; Rosa Illario; Andrea Rando; Paola di Gregorio; Piero Masina; Luigi Ramunno

doi:10.1017/S0022029903006101

Abstract

Caseins (αs1, β, αs2, e κ) represent about 80% of the whole protein content of ruminant milk. Each of these proteins is encoded by single copy genes (CSN1S1, CSN2, CSN1S2 and CSN3, respectively) clustered on a ∼200-kb segment of chromosome 6 (Ferretti et al. 1990; Gallagher et al. 1994) in the order: CSN1S1, CSN2, CSN1S2 and CSN3 (Mercier & Vilotte, 1993). Furthermore, in cattle and goat CSN1S1 and CSN2 are convergently transcribed (Leroux & Martin, 1996; Rijnkles et al. 1997) and are only 20 and 12 kb apart, respectively.

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Ramunno, Luigi Cosenza, Gianfranco Rando, Andrea Illario, Rosa Gallo, Daniela Berardino, Dino Di and Masina, Piero 2004. The goat αs1-casein gene: gene structure and promoter analysis. Gene, Vol. 334, Issue. , p. 105.

Cunsolo, Vincenzo Galliano, Francesco Muccilli, Vera Saletti, Rosaria Marletta, Donata Bordonaro, Salvatore and Foti, Salvatore 2005. Detection and characterization by high‐performance liquid chromatography and mass spectrometry of a goat β‐casein associated with a CSN2 null allele. Rapid Communications in Mass Spectrometry, Vol. 19, Issue. 20, p. 2943.

Ramunno, Luigi Cosenza, Gianfranco Rando, Andrea Pauciullo, Alfredo Illario, Rosa Gallo, Daniela Di Berardino, Dino and Masina, Piero 2005. Comparative analysis of gene sequence of goat CSN1S1 F and N alleles and characterization of CSN1S1 transcript variants in mammary gland. Gene, Vol. 345, Issue. 2, p. 289.

Caroli, A. Chiatti, F. Chessa, S. Rignanese, D. Bolla, P. and Pagnacco, G. 2006. Focusing on the Goat Casein Complex. Journal of Dairy Science, Vol. 89, Issue. 8, p. 3178.

Sztankóová, Z. Kott, T. Czerneková, V. Dudková, G. Mátlová, V. and Soldát, J. 2006. A new allele specific polymerase chain reaction method (AS-PCR) for detection of the goat CSN1S101 allele. Small Ruminant Research, Vol. 66, Issue. 1-3, p. 282.

Marletta, Donata Criscione, Andrea Bordonaro, Salvatore Guastella, Anna Maria and D'Urso, Giuseppe 2007. Casein polymorphism in goat's milk. Le Lait, Vol. 87, Issue. 6, p. 491.

Caroli, A. Chiatti, F. Chessa, S. Rignanese, D. Ibeagha-Awemu, E.M. and Erhardt, G. 2007. Characterization of the Casein Gene Complex in West African Goats and Description of a New αs1-Casein Polymorphism. Journal of Dairy Science, Vol. 90, Issue. 6, p. 2989.

Sztankóová, Z. Mátlová, V. and Malá, G. 2007. Genetic polymorphism at the CSN1S1 gene in two Czech goat breeds. Czech Journal of Animal Science, Vol. 52, Issue. 7, p. 199.

Ibeagha-Awemu, Eveline M. Kgwatalala, Patrick and Zhao, Xin 2008. A critical analysis of production-associated DNA polymorphisms in the genes of cattle, goat, sheep, and pig. Mammalian Genome, Vol. 19, Issue. 9, p. 591.

Gigli, I. Maizon, D.O. Riggio, V. Sardina, M.T. and Portolano, B. 2008. Short Communication: Casein Haplotype Variability in Sicilian Dairy Goat Breeds. Journal of Dairy Science, Vol. 91, Issue. 9, p. 3687.

Cosenza, G. Pauciullo, A. Gallo, D. Colimoro, L. D’Avino, A. Mancusi, A. and Ramunno, L. 2008. Genotyping at the CSN1S1 locus by PCR-RFLP and AS-PCR in a Neapolitan goat population. Small Ruminant Research, Vol. 74, Issue. 1-3, p. 84.

Silva, M.M.C. Torres, R.A. Rodrigues, M.T. Soares, M.A.M. Magalhães, A.C.M. Silva, S.P. and Silveira, T.S. 2009. Efeito dos genótipos para alphaS1-caseína sobre as frações proteicas e lipídicas do leite de cabra. Arquivo Brasileiro de Medicina Veterinária e Zootecnia, Vol. 61, Issue. 3, p. 682.

Guastella, Anna Maria Criscione, Andrea Zuccaro, Antonio Tidona, Flavio Marietta, Donata and Bordonaro, Salvatore 2009. Genetic polymorphism of CSN1S1 and CSN2 loci in Rossa Mediterranea goat population. Italian Journal of Animal Science, Vol. 8, Issue. sup3, p. 101.

Maga, E. A. Daftari, P. Kültz, D. and Penedo, M. C. T. 2009. Prevalence of αs1-casein genotypes in American dairy goats1. Journal of Animal Science, Vol. 87, Issue. 11, p. 3464.

Soares, Maria Amélia Menck Rodrigues, Marcelo Teixeira Mognol, Giuliana Patrícia Ribeiro, Lucinéia de Fátima Chasko Silva, José Luis da Conceição and Brancalhão, Rose Meire Costa 2009. Polymorphism of alpha s1-casein gene in a dairy goat herd in the southeastern region of Brazil. Revista Brasileira de Zootecnia, Vol. 38, Issue. 6, p. 1026.

Küpper, Julia Chessa, Stefania Rignanese, Daniela Caroli, Anna and Erhardt, Georg 2010. Divergence at the casein haplotypes in dairy and meat goat breeds. Journal of Dairy Research, Vol. 77, Issue. 1, p. 56.

Pagano, Renato Italo Pennisi, Pietro Valenti, Bernardo Lanza, Massimiliano Di Trana, Adriana Di Gregorio, Paola De Angelis, Anna and Avondo, Marcella 2010. Effect of CSN1S1 genotype and its interaction with diet energy level on milk production and quality in Girgentana goats fed ad libitum. Journal of Dairy Research, Vol. 77, Issue. 2, p. 245.

Yue, X. P. Zhang, X. M. Wang, W. Ma, R. N. Deng, C. J. Lan, X. Y. Chen, H. Li, F. Xu, X. R. Ma, Y. and Lei, C. Z. 2011. The CSN1S1 N and F alleles identified by PCR-SSCP and their associations with milk yield and composition in Chinese dairy goats. Molecular Biology Reports, Vol. 38, Issue. 4, p. 2821.

Martin, P. Bianchi, L. Cebo, C. and Miranda, G. 2013. Advanced Dairy Chemistry. p. 463.

Bonanno, A. Di Grigoli, A. Di Trana, A. Di Gregorio, P. Tornambè, G. Bellina, V. Claps, S. Maggio, G. and Todaro, M. 2013. Influence of fresh forage-based diets and αS1-casein (CSN1S1) genotype on nutrient intake and productive, metabolic, and hormonal responses in milking goats. Journal of Dairy Science, Vol. 96, Issue. 4, p. 2107.

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Molecular characterization of the goat CSN1S101 allele

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Molecular characterization of the goat CSN1S101 allele

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