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Changes in surface antigens of Hymenolepis nana during differentiation and maturation in mice

Published online by Cambridge University Press:  05 June 2009

A. Ito  and
K. Onitake
A. Ito
Affiliation:
Department of Parasitology, Gifu University School of Medicine, Gifu 500
K. Onitake
Affiliation:
Department of Biology, Faculty of Science, Yamagata University, Yamagata 990, Japan
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Abstract

The surface antigens of oncosphere, cysticercoid, adult scolex and adult strobila (other than scolex) of Hymenolepis nana differ critically from one another. When the oncosphere of H. nana undergoes differentiation and development into the mature tapeworm, the infected mouse first produces anti-oncosphere antibody, followed by anti-cysticercoid, anti-adult scolex and finally anti-strobila (other than scolex region) antibodies of IgG, IgM and IgA isotypes as detected by indirect immunofluorescent antibody test. The parasite changed its surface antigens throughout its differentiation and maturation, and all developmental stages were recognized by the infected mouse host. However, there appeared no further changes in surface antigens during aging after maturation. The antibody responses were always delayed compared with the differentiation and maturation of the parasite.

Keywords

Hymenolepis nanasurface antigensdevelopmentmouse
Type
Research Papers
Information
Journal of Helminthology , Volume 61 , Issue 2 , June 1987 , pp. 129 - 136
Copyright
Copyright © Cambridge University Press 1987

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