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Experimental infection in a human subject by a possibly undescribed species of Taenia in Taiwan

Published online by Cambridge University Press:  05 June 2009

David Chao ,
Ming M. Wong  and
Ping-Chin Fan
David Chao
Affiliation:
Department of Parasitology, National Yang-Ming Medical College, Taipei 11221, Taiwan, Republic of China
Ming M. Wong
Affiliation:
Department of Veterinary Microbiology and Immunology, University of California, Davis, California 95626, USA
Ping-Chin Fan
Affiliation:
Department of Parasitology, National Yang-Ming Medical College, Taipei 11221, Taiwan, Republic of China
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Abstract

A cysticercus of a possibly undescribed species of Taenia which occurs commonly in Taiwan aborigines was used to establish an experimental infection in a human volunteer. Symptomatic effects attributed to the infection included diarrhoea, upper abdominal pain, and increase or loss of appetite over a four-month period. After an expelled proglottid was observed 122 days post-exposure, eggs and proglottids were found continuously until the patient was treated with anthelmintics. Antibody titres measured by enzyme-linked immunosorbent assay and levels of eosinophilia seemed to correlate with symptoms. Haematological analyses revealed an abnormal lipid metabolism during the entire symptomatic period.

Keywords

TaeniaTaiwanmanexperimental infection
Type
Research Papers
Information
Journal of Helminthology , Volume 62 , Issue 3 , September 1988 , pp. 235 - 242
Copyright
Copyright © Cambridge University Press 1988

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References

REFERENCES

Chao, D. & Fan, P. C. (1986) Larval stage of a possible new species of tapeworm from Taiwan aborigines. Chinese Bioscience, 27, 1–6.Google Scholar
Chung, W. C. & Liu, J. C. (1971) Survey and treatment of Taenia saginata with atabrine in aborigines in Wufeng District, Hsinchu County, Taiwan. Chinese Journal of Microbiology, 4, 45–49.Google Scholar
Gleich, G. J., Frigas, E., Loegering, D. A., Wassom, D. L. & Steinmuller, D. (1979) Cytotoxic properties of the eosinophil major basic protein. Journal of Immunology, 123, 2925–2927.Google Scholar
Huang, S. W. (1967) Studies on Taenia species prevalent among the aborigines in Wulai District, Taiwan. II. On the species of Taenia. Bulletin of the Institute of Zoology Academia Sinica, 6, 29–34.Google Scholar
Liu, H. Y., Chao, D. & Fan, P. C. (1981) Prevalence and chemotherapy of taeniasis among the aborigines in Nan-ao District, I-Ian County, Northeastern Taiwan. Proceedings of the National Science Council, Republic of China, 5, 188–195.Google Scholar
Pawlowski, Z. S. (1982) Taeniasis and cysticercosis. In: CRC Handbook Series in Zoonoses, Parasitic Zoonoses. Vol.I., editor, Fallis, A. M. pp. 313–348. CRC Press: Boca Raton.Google Scholar
Ruitenberg, E. J., Steerenberg, R. A. & Brosi, B. J. (1975) Microsystem for the application of ELISA (enzyme-linked immunosorbent assay) in the serodiagnosis of Trichinella spiralis infections. Medikon Nederland, 4, 30–31.Google Scholar
Schmidt, G. D. & Roberts, L. S. (1985) Tapeworms. In: Foundations of Parasitology, 3rd edition, pp. 373–408. Times Mirror/Mosby College Publishing: Saint Louis.Google Scholar
Wassom, D. L. & Gleich, G. J. (1979) Damage to Trichinella spiralis newborn larvae by eosinophil major basic protein. American Journal of Tropical Medicine and Hygiene, 28, 860–863.Google Scholar
Yokogawa, S. (1935) On the taeniasis saginata among the aborigines in Taiwan. Nippon Gakujits Kyokai Hohoku, 10, 497–500.Google Scholar
Yoshimura, K., Uchida, K., Sato, K. & Oya, H. (1984) Ultrastructural evidence for eosinophil-mediated destruction of Angiostrongylus cantonensis transferred into the pulmonary artery of nonpermissive host. Parasite Immunology, 6, 105–118.CrossRefGoogle Scholar
Yu, J. C. & Kao, C. Y. (1982) Present status of intestinal parasitic infections and head louse infestation among aborigines of Lan-yu (Orchid Island), Taiwan. Journal of Formosan Medical Association, 81, 408–413.Google Scholar