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Study of the effects of insulin on the migration of Hymenolepls diminuta in rats

Published online by Cambridge University Press:  05 June 2009

C. H. Cho
C. H. Cho
Affiliation:
Laboratory of Pharmacology, Department of Medical Research, Veterans General Hospital, Taipei, Taiwan, Republic of China
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Abstract

The effects of insulin on worm (Hymenolepls diminuta) migration was studied. Insulin injection (20 U/kg, s.c.) significantly increased gastric acid output but did not affect the serotonin content of blood, intestinal lumen or worms. The drug produced, dose-dcpcndcntly, postcriad migration of the worms in rats without pylorusligation but ligation of the pylorus prevented this migration. It is concluded that the hypcrsccrction of gastric acid induced by insulin is responsible for the postcriad migration of H. diminuta in rats.

Type
Research Article
Information
Journal of Helminthology , Volume 58 , Issue 4 , December 1984 , pp. 291 - 293
Copyright
Copyright © Cambridge University Press 1984

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References

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