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Antifilarial effect of Zingiber officinale on Dirofilaria immitis

Published online by Cambridge University Press:  05 June 2009

Anita Datta  and
Nirmal C. Sukul
Anita Datta
Affiliation:
Department of Zoology, Visva-Bharati University, Santiniketan 731235, West Bengal, India
Nirmal C. Sukul
Affiliation:
Department of Zoology, Visva-Bharati University, Santiniketan 731235, West Bengal, India
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Abstract

Dogs, naturally infected with Dirofilaria immitis, were treated with the residues of the alcoholic extracts of the rhizomes of Zingiber officinale (ginger). Twelve subcutaneous injections of the extract given at 100 mg/kg reduced microfilarial concentration in blood by a maximum of 98%. Fifty five days after the last injection there was 83% reduction in microfilarial concentration suggesting partial destruction of adult worms. Half of the treated dogs showed some lethargy at the beginning of treatment possibly due to the mass annihilation of microfilariae in blood.

Keywords

Dirofilaria immitisdogZingiber officinaleantifilarialsplant extracts
Type
Research Note
Information
Journal of Helminthology , Volume 61 , Issue 3 , September 1987 , pp. 268 - 270
Copyright
Copyright © Cambridge University Press 1987

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References

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