Hostname: page-component-78c5997874-mlc7c Total loading time: 0 Render date: 2024-11-11T09:41:11.927Z Has data issue: false hasContentIssue false
  • English
  • Français

Antifilarial effect of Zingiber officinale on Dirofilaria immitis

Published online by Cambridge University Press:  05 June 2009

Anita Datta  and
Nirmal C. Sukul
Anita Datta
Affiliation:
Department of Zoology, Visva-Bharati University, Santiniketan 731235, West Bengal, India
Nirmal C. Sukul
Affiliation:
Department of Zoology, Visva-Bharati University, Santiniketan 731235, West Bengal, India
Get access Rights & Permissions [Opens in a new window]

Abstract

Dogs, naturally infected with Dirofilaria immitis, were treated with the residues of the alcoholic extracts of the rhizomes of Zingiber officinale (ginger). Twelve subcutaneous injections of the extract given at 100 mg/kg reduced microfilarial concentration in blood by a maximum of 98%. Fifty five days after the last injection there was 83% reduction in microfilarial concentration suggesting partial destruction of adult worms. Half of the treated dogs showed some lethargy at the beginning of treatment possibly due to the mass annihilation of microfilariae in blood.

Keywords

Dirofilaria immitisdogZingiber officinaleantifilarialsplant extracts
Type
Research Note
Information
Journal of Helminthology , Volume 61 , Issue 3 , September 1987 , pp. 268 - 270
Copyright
Copyright © Cambridge University Press 1987

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Dutta, A. & Sukul, N. C. (1982) Filaricidal properties of a wild herb, Andrographis paniculata. Journal of Helminthology, 56, 81–84.CrossRefGoogle ScholarPubMed
Partono, F., Purnomo, & Soewarta, A. (1979) A single method to control Brugia timori by diethylcarbamazine administration. Transactions of the Royal Society of Tropical Medicine and Hygiene, 75, 536–542.CrossRefGoogle Scholar
Raj, R. K. (1974) Screening of some indigenous plants for anthelmintic action against human Ascaris lumbricoides. Indian Journal of Physiology and Pharmacology, 18, 129–131.Google ScholarPubMed
Rollo, I. M. (1970) Drugs used in the chemotherapy of helminthiasis. In: The Pharmacological Basis of Therapeutics, 4th ed. (editors Goodman, L. S. and Gilman, A.) pp. 1067–1094. The Macmillan Co.: London.Google Scholar
Sukul, N. C., Das, P. K. & De, G. C. (1974) Nematicidal action of some edible crops. Nematologica, 20, 187–191.CrossRefGoogle Scholar
World Health Organization (1985) Newsletter, Special Programme for research and training in tropical diseases. No. 22. Special Issue: TDR Workplans.Google Scholar