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Eosinophilia in Ascaris suum-reinfected mice

Published online by Cambridge University Press:  05 June 2009

Kazuo Sugane
Kazuo Sugane
Affiliation:
Department of Parasitology, Faculty of Medicine, Shinshu University, 3–1–1 Asahi, Matsumoto City, Nagano Prefecture, Japan
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Abstract

The secondary response of eosinophilia has been studied in mice infected with A. suum. In mice infected orally with 1000 A. suum eggs, larvae disappeared from the body within two weeks after infection. The number of peripheral blood eosinophils decreased to the pre-infection level within eight weeks. A typical secondary response of IgG antibody production to egg antigen was found after reinfection with 1000 eggs. The number of peripheral blood eosinophils increased more rapidly after reinfection than after the primary infection. However, the peak number of eosinophils after reinfection was similar to that after primary infection, and the long-lasting characteristics of eosinophilia after reinfection did not differ from those after primary infection. These results suggest that the secondary response of eosinophilia is characterized by a rapid increase in the number of eosinophils in A. suum-reinfected mice.

Keywords

Ascaris suumeosinophiliamousesecondary responseIgG antibodyegg antigen
Type
Research Papers
Information
Journal of Helminthology , Volume 62 , Issue 1 , March 1988 , pp. 51 - 57
Copyright
Copyright © Cambridge University Press 1988

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