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Experimental infections with Nematodirus spathiger in rabbits

Published online by Cambridge University Press:  05 June 2009

H. Hoste  and
G. Fort
H. Hoste
Affiliation:
C. R. INRA Tours-Nouzilly, Station de Pathologie Aviaire et de Parasitologie, F-37380 Nouzilly, France
G. Fort
Affiliation:
C. R. INRA Tours-Nouzilly, Station de Pathologie Aviaire et de Parasitologie, F-37380 Nouzilly, France
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Abstract

The feasibility of infecting laboratory rabbits experimentally with the ovine nematode Nematodirus spathiger was examined. Eight-week-old rabbits were dosed either with 5000 or with 17 000 third-stage larvae and killed on days 10, 21 or 42 post-infection. With the lower dose, 20 to 40% of the inoculum were recovered at necropsy. Similar values were recovered at necropsy. Similar values were observed with the 17 000 dose on days 10 and 21 post-infection, but on day 42 the worm population was residual (0·6%). With both dose levels, during the course of infection, the worm populations were mainly composed of fourth-stage larvae and worm egg excretion was low. N. spathiger mainly inhabited the proximal jejunum. The results were compared with N. spathiger infection in sheep to assess the usefulness of the rabbit as an experimental model for Nematodirus infection.

Keywords

Nematodirus spathigerrabbitexperimental modelNematoda
Type
Research Article
Information
Journal of Helminthology , Volume 66 , Issue 3 , September 1992 , pp. 227 - 230
Copyright
Copyright © Cambridge University Press 1992

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