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Fasciolosis in South America: epidemiology and control challenges

Published online by Cambridge University Press:  09 September 2016

C. Carmona  and
J.F. Tort
C. Carmona
Affiliation:
Unidad de Biología Parasitaria, Departamento de Biología Celular y Molecular, Facultad de Ciencias, Instituto de Higiene, Universidad de la Republica, UDELAR, Av. Alfredo Navarro 3051 CP 11600, Montevideo, Uruguay
J.F. Tort*
Affiliation:
Departamento de Genética, Facultad de Medicina, Universidad de la Republica, UDELAR, Avda. Gral. Flores 2125, CP 11800, Montevideo, Uruguay
*
*E-mail: jtort@fmed.edu.uy
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Abstract

Fasciolosis caused by Fasciola hepatica severely affects the efficiency of livestock production systems worldwide. In addition to the economic impact inflicted on livestock farmers, fasciolosis is an emergent zoonosis. This review emphasizes different aspects of the disease in South America. Available data on epidemiology in bovines and ovines in different countries, as well as a growing body of information on other domestic and wildlife definitive hosts, are summarized. The issue of drug resistance that compromises the long-term sustainability of current pharmacological strategies is examined from a regional perspective. Finally, efforts to develop a single-antigen recombinant vaccine in ruminants are reviewed, focusing on the cases of leucine aminopeptidase or thioredoxin glutathione reductase.

Type
Review Article
Information
Journal of Helminthology , Volume 91 , Issue 2 , March 2017 , pp. 99 - 109
Copyright
Copyright © Cambridge University Press 2016 

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