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Immunological aspects in the rejection process of Hymenolepis muris-sylvaticae from CFLP and NMRI mice

Published online by Cambridge University Press:  05 June 2009

C. Van Haeren  and
P. H. De Rycke
C. Van Haeren
Affiliation:
Laboratory of Zoophysiology, State University of GentK.L. Ledeganckstraat35, B-9000 Gent Belgium
P. H. De Rycke
Affiliation:
Laboratory of Zoophysiology, State University of GentK.L. Ledeganckstraat35, B-9000 Gent Belgium
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Abstract

When mice were treated with 1–25 mg cortisone acetate thrice weekly, recovery of Hymenolepis murissylvaticae was significantly higher than in untreated controls, both in oral infections with six cysticercoids and surgical transplantations of one 7-day or 8-day-old worm. Cortisone treatment also resulted in the worms being located more anteriorly in the small intestine.Evidence of an immunological response against the tapeworm in the intestine is given by: (a) an accelerated rejection of a secondary oral cysticercoid infection and a significant difference of the dry weights of the worms recovered on day 10 in CFLP mice; (b) an accelerated rejection of a secondary surgical infection on days 4 and 6 in CFLP mice and on days 3 and 4 in NMRI mice; (c) an accelerated rejection of a secondary surgical infection given 3 and 6 months after the primary immunizing infection in SWlSS-albino mice.

Keywords

Hymenolepis murissylvaticaecortisonemouserejection
Type
Research Article
Information
Journal of Helminthology , Volume 60 , Issue 3 , September 1986 , pp. 179 - 186
Copyright
Copyright © Cambridge University Press 1986

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References

REFERENCES

Befus, A. D. (1975) Secondary infections of Hymenolepis diminuta in mice: effects of varying worm burdens in primary and secondary infections. Parasitology, 71, 61–75.CrossRefGoogle ScholarPubMed
Hopkins, C. A., Grant, P. M. & Stallard, H. E. (1973) The effect of oxyclozanide on Hymenolepis microstoma and H. diminuta. Parasitology, 66, 355–365.CrossRefGoogle ScholarPubMed
Hopkins, C. A. & Stallard, H.E. (1974) Immunity to intestinal tapeworms: the rejection of Hymenolepis citelli by mice. Parasitology, 69, 63–76.CrossRefGoogle ScholarPubMed
Hopkins, C. A. & Stallard, H. E. (1976) The effect of cortisone on the survival of Hymenolepis diminuta in mice. Rice University Studies, 62, 145–159.Google Scholar
Hopkins, C. A., Subramanian, G. & Stallard, H. (1972a) The development of Hymenolepis diminuta in primary and secondary infections in mice. Parasitology, 64,401–412.CrossRefGoogle ScholarPubMed
Hopkins, C. A., Subramanian, G. & Stallard, H. (1972b) The effect of immunosuppressants on the development of Hymenolepis diminuta in mice. Parasitology, 65, 111–120.Google ScholarPubMed
Hopkins, C. A. & Zajac, A. (1976) Transplantation of Hymenolepis diminuta into naieve, immune and irradiated mice. Parasitology, 73, 73–81.CrossRefGoogle Scholar
Howard, R. J. (1976) The growth of secondary infections of Hymenolepis microstoma in mice: the effect of various primary infection regimes. Parasitology, 72, 317–323.CrossRefGoogle ScholarPubMed
Khan, Z. I. & De Rycke, P. H. (1977) The effect of cortisone acetate on the metabolism of Hymenolepis microstoma (Cestoda: Cyclophyllidea). Zeitschrift fur Parasitenkunde, 52, 267–274.CrossRefGoogle Scholar
Lucas, S. B., Hassounah, B., Müller, R. & Doenhoff, M. J. (1980) Abnormal development of Hymenolepis nana larvae in immunosuppressed mice. Journal of Helminthology, 54, 75–82.CrossRefGoogle ScholarPubMed
Moss, G. D. (1971) The nature of the immune response of the mouse to the bile duct cestode Hymenolepis Microstoma. Parasitology, 62, 285–294.CrossRefGoogle Scholar
Moss, G. D. (1972) The effect of cortisone treatment on the growth of Hymenolepis microstoma in mice. Parasitology, 64, 311–320.CrossRefGoogle ScholarPubMed
Siegel, G. (1956) In: Nonparametric statistics for the behavioural sciences. New York: McGraw-Hill Book Company, Inc.Google Scholar
Tan, B. D. & Jones, A. W. (1968) Resistance of mice to reinfection with the bile duct cestode, Hymenolepis microstoma. Experimental Parasitology, 22, 250–255.Google ScholarPubMed
Van Haeren, C. & De Rycke, P. H. (1984) Hymenolepis muris-sylvaticae in laboratory rodents. Journal of Helminthology, 58, 31–37.CrossRefGoogle ScholarPubMed
Walkey, M., Simmons, D. J. C. & Nasher, A. K. (1980) Observations on the host specificity of Hymenolepis straminae (Goeze). Journal of Parasitology, 66, 420–423.CrossRefGoogle Scholar