Hostname: page-component-cd9895bd7-fscjk Total loading time: 0 Render date: 2024-12-27T10:48:16.829Z Has data issue: false hasContentIssue false
  • English
  • Français

The mouse as a suitable host for an isolate of Schistosoma haematobium from Niger

Published online by Cambridge University Press:  05 June 2009

D. Imbert-Establet ,
C. Vera ,
B. Sellin  and
J. Jourdane
D. Imbert-Establet
Affiliation:
Laboratoire de Biologie Animale, Centre de Biologie et d'ecologie Tropicale et Méditerranéenne, U.R.A. CNRS 698, Université, Avenue de Villeneuve, 66860 Perpignan Cedex, France
C. Vera
Affiliation:
Laboratoire des schistosomoses O.C.C.G.E.–O.R.S.T.O.M., B.P. 10887 Niamey, Niger
B. Sellin
Affiliation:
Laboratoire des schistosomoses O.C.C.G.E.–O.R.S.T.O.M., B.P. 10887 Niamey, Niger
J. Jourdane
Affiliation:
Laboratoire de Biologie Animale, Centre de Biologie et d'ecologie Tropicale et Méditerranéenne, U.R.A. CNRS 698, Université, Avenue de Villeneuve, 66860 Perpignan Cedex, France
Get access Rights & Permissions [Opens in a new window]

Abstract

The host-parasite relationships of a Schistosoma haematobium isolate, originating from Niger, and the white mouse are described. Swiss OF1 albino mice were exposed individually to 200 cercariae and worms were recovered 9, 12, 16 and 20 weeks post infection. The mean worm returns ranged between 10·54 and 13·5% and did not alter significantly between 9 and 20 weeks post infection. The sex ratio of worms was always in favour of males; from 7·9:1 at 9 weeks after infection it decreased regularly to 3·28:1 at 20 weeks. Male worms reached a mean length of 8·72 mm at 20 weeks. From the 12th week post infection, a high number of eggs was found in the liver and gut. At 20 weeks, eggs were also found in the bladder. Viable eggs and infective miracidia were obtained. The infection of Bulinus truncatus from Niger succeeded with a mean rate of 61% after the first passage through mice. The isolate of S. haematobium was maintained in the laboratory during 3 successive passages through mice. These entirely new results are very probably linked to genetic characteristics peculiar to the S. haematobium populations from Niger.

Keywords

Schistosoma haematobiummousemiracidium infectivityNigerhost-parasite relationshipsTrematoda
Type
Research Article
Information
Journal of Helminthology , Volume 66 , Issue 1 , March 1992 , pp. 1 - 6
Copyright
Copyright © Cambridge University Press 1992

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Agnew, A. M., Lucas, S. B. & Doenhoff, M. J. (1988) The host-parasite relationship of Schistosoma haematobium in CBA mice. Parasitology, 97, 403–424.CrossRefGoogle ScholarPubMed
Capron, A., Deblock, S., Biguet, J., Clay, A., Adenis, L. & Vernes, A. (1965) Contribution à l'étude expérimentale de la Bilharziose à; Schistosoma haematobium. Bulletin of the World Health Organization, 32, 755–778.Google Scholar
Cheever, A. W., Duvall, R. H. & Hallack, T. A. (1983) Hepatic fibrosis in Schistosoma haematobium infected mice. Transactions of the Royal Society of Tropical Medicine and Hygiene, 77, 673–679.CrossRefGoogle ScholarPubMed
Duwall, R. H. & Dewitt, W. B. (1967) An improved perfusion technique for recovering adult schistosomes from laboratory animals. American Journal of Parasitology, 7, 293–297.Google Scholar
Mitchell, G. F., Garcia, E. G., Wood, S. M., Diasanta, R., Almonte, A. R., Calica, E., Davern, K. M. & Tiu, W. U. (1990) Studies on the sex ratio of worms in schistosome infection. Parasitology, 101, 27–34.Google Scholar
Moore, D. V. & Meleney, A. I. (1954) Comparative susceptibility of common laboratory animals to experimental infection with Schistosoma haematobium. Journal of Parasitology, 40, 392–397.CrossRefGoogle ScholarPubMed
Taylor, M. G. & Andrews, B. J. (1973) Comparison of the infectivity and pathogenicity of six species of African schistosomes and their hybrids. I. Mice and hamsters. Journal of Helminthology, 47, 439–453.Google Scholar
Vera, C., Jourdane, J., Sellin, B. & Combes, C. (1990) Genetic variability in the compatibility between Schistosoma haematobium and its potential vectors in Niger. Epidemiological implications. Tropical Medicine and Parasitology, 41, 143–148.Google ScholarPubMed
Wright, C. A. & Knowles, R. J. (1972) Studies on Schistosoma haematobium in the laboratory. III. Strains from Iran, Mauritius and Ghana. Transactions of the Royal Society of Tropical Medicine and Hygiene, 66, 108–118.Google Scholar