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Schistosomiasis in the Senegal River Basin: before and after the construction of the dams at Diama, Senegal and Manantali, Mali and future prospects

Published online by Cambridge University Press:  05 June 2009

V.R. Southgate
V.R. Southgate
Affiliation:
Department of Zoology, The Natural History Museum, Cromwell Road, South Kensington, London, SW7 5BD, UK
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Abstract

Ecological changes in the Senegal River Basin (SRB) resulting from the construction of a barrage at Diama, Senegal on the Senegal River to prevent the intrusion of sea water into the river, and a dam at Manantali, Mali on the Bafing River to control the flow of water and to generate electricity, have been responsible for changes in the epidemiology of human schistosomiasis. The introduction of Schistosoma mansoni into the Lower and Middle Valleys of the SRB and subsequent spread of the parasite in the human population is recorded with regard to prevalence and intensity. New foci of S. haematobium are described. The reduction in salinity and change from an acidic to an alkaline environment in the water are beneficial to both the fecundity and growth of freshwater snails and transmission of the parasite. The creation of new irrigation canals and expansion of the rice fields have provided new habitats for intermediate hosts to colonize. The evidence for praziquantel resistance/tolerance by populations of S. mansoni and the possibilities of the development, production and testing of a vaccine against human schistosomiasis are discussed. Future studies will monitor the spread of human urinary and mesenteric schistosomiasis in the SRB, will evaluate further the presence of praziquantel resistance/tolerance in S. mansoni, will examine the heavily infected human population for pathological symptoms and determine the most appropriate methods to control this severe outbreak of human schistosomiasis.

Type
Symposium Papers
Information
Journal of Helminthology , Volume 71 , Issue 2 , June 1997 , pp. 125 - 132
Copyright
Copyright © Cambridge University Press 1997

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References

Belot, J., Geerts, S. & Diouf, M. (1993) Observations on the population dynamics of snail hosts for schistosomes in the delta of the Senegal River Basin. Journal of Molluscan Studies 59, 7–13.Google Scholar
Capron, A., Dessaint, J.P., Capron, M. & Pierce, R.J. (1992) ‘Vaccine strategies against schistosomiasis’. Memorias do Instituto Oswalds Cruz 87, 1–9.CrossRefGoogle ScholarPubMed
Chaine, J.P. & Malek, E.A. (1983) Urinary schistosomiasis in the sahelian region of the Senegal River Basin. Tropical and Geographical Medicine 35, 249–256.Google Scholar
Christensen, N.Ø., Frandsen, F. & Nansen, P. (1979). The effects of some environmental conditions and final-host and parasite-related factors on the penetration of Schistosoma mansoni cercariae into mice. Zeitschrift für Parasitenkunde 59, 267–275.CrossRefGoogle ScholarPubMed
Cisse, F., Diallo, S. & Dieny, M. (1983) Bilan actuel de la bilharziose urinaire chez les populations riveraines du Lac de Guiers. Dakar Médical 28, 343–350.Google Scholar
De Clercq, D. (1996) The epidemiology and control of human schistosomiasis and geohelminthiasis in Mali, West Africa. PhD Thesis, University of Gent, Belgium.Google Scholar
Diaw, O.T., (1980) Trématodoses dans le delta du Sénégal et le ac de Guiers. 1. Étude de la répartition des mollusques d'eau douce. Bulletin de l'Institute Française Afrique Noire, Serie A, Science Nature 42, 709–722.Google Scholar
Diaw, O.T., Vassiliades, G., Seye, M. & Sarr, Y. (1990) Prolifération de mollusques et incidence sur les trématodoses dans la region du Delta et du Lac de Guiers aprés la construction du barrage de Diama sur le fleuve Sénégal. Bulletin de la Société Française Parasitologie, Supplement 2, 8, pp.772 (ICOPA V1 1).Google Scholar
Diaw, O.T., Vassiliades, G., Seye, M. & Sarr, Y. (1991) Epidémiologie de la bilharziose intestinale a Schistosoma mansoni a Richard-Toll (Delta du Fleuve Sénégal) étude malacologique. Bulletin de la Société Pathologie Exotique 84, 174–183.Google Scholar
Donnelly, F.A., Appleton, C.G. & Schutte, C.H.J. (1983) The influence of salinity on certain aspects of the biology of Bulinus (Physopsis) africanus. International Journal for Parasitology 13, 539–545.CrossRefGoogle ScholarPubMed
Donnelly, F.A., Appleton, C.G. & Schutte, C.H.J. (1984) The influence of salinity on the ova and miracidia of three species of Schistosoma. International Journal for Parasitology 13, 539–545.Google Scholar
Fallon, P.G. & Doenoff, M.J. (1994) Drug-resistant schistosomiasis: resistance to praziquantel and oxaminiquine induced in Schistosoma mansoni is drug specific. American Journal of Tropical Medicine & Hygiene 53, 83–88.Google Scholar
Fallon, P.G., Sturrock, R.F., Capron, A., Niang, M. & Doenhoff, M.J. (1995) Short report: Diminished susceptibility to praziquantel in a Senegal isolate of Schistosoma mansoni. American Journal of Tropical Medicine and Hygiene 53, 61–62.Google Scholar
Kardoff, R., Stelma, F.F., Vocke, A.K., Yazdanpanah, Y., Thomas, A.K., Mbaye, A., Talla, I., Niang, M., Enrich, J.H.H., Doehring, E. & Gryseels, B. (1996) Ultrasonography in a Senegalese community recently exposed to Schistosoma mansoni infection. American Journal of Tropical Medicine and Hygiene 54, 586–590.CrossRefGoogle Scholar
Imbert-Establet, D. (1986) Approche synthétique du rôle des rongeurs sauvages dans la transmission de Schistosoma mansoni: Résultats démographiques, écologiques, immunologiques et génétiques. Thèse de Doctoral d'Etat, Université de Perpignan.Google Scholar
Ismail, M.M., Taha, S.A., Arghaly, A.M. & el-Azony, A.S. (1994) Laboratory induced resistance to praziquantel in experimental schistosomiasis. Journal of the Egyptian Society of Parasitology 24, 685–695.Google ScholarPubMed
Malek, E. & Chaine, J.P. (1989) Effects of the developments in the Senegal River Basin on the prevalence and spread of schistosomiasis. pp. 181–192in Service, M.W. (Ed.) Demography and vector borne diseases. Boca Raton, Florida, CRC Press.Google Scholar
Meir-Brook, C., Hass, D., Wister, G. & Zeller, T. (1987) Hydrochemical factors limiting the distribution of Bulinus truncatus (Pulmonata; Planorbidae). American Malacological Bulletin 5, 85–90.Google Scholar
Miller, M. (1982) Parasites of man and arthropod disease vectors in communities of a water development program on the Senegal River Basin. pp. 279–334in Meerovich, E. (Ed.) Aspects of parasitology - a festschrift dedicated to the fiftieth anniversary of the Institute of Parasitology of McGill University 1932–1982. McGill University, Canada.Google Scholar
Picquet, M., Ernould, J.C., Vercruysse, J., Southgate, V.R., Mbaye, A., Sambou, B., Niang, M. & Rollinson, D. (1996) The epidemiology of human schistosomiasis in the Senegal River Basin. Transactions of the Royal Society of Tropical Medicine and Hygiene 90, 440–446.Google Scholar
Rey, L. (1993) Non human vertebrate hosts for Schistosoma mansoni and schistosomiasis transmission in Brazil. Research and Reviews in Parasitology 53, 13–25.Google Scholar
Rouquet, P., Verlé, P., Kongs, A., Talla, I. & Niang, M. (1993) Hepatosplenic alterations determined by ultrasonography in a population recently infected with Schistosoma mansoni in Richard-Toll, Senegal. Transactions of the Royal Society of Tropical Medicine and Hygiene 87, 190–193.CrossRefGoogle Scholar
Sène, M., Brémond, P., Hervé, J.P., Southgate, V.R., Sellin, B., Marchand, B. & Duplantier, J.M. (in press) Comparison of human and murine isolates of Schistosoma mansoni from Richard-Toll, Senegal, by isoelectric focusing. Journal of Helminthology.Google Scholar
Schneider, C.R. & Malek, E.A. (1984) B. pfeifferi in Eastern Senegal region, Department of Kedougou, Republic of Senegal. Transactions of the Royal Society of Tropical Medicine and Hygiene 78, 565–566.Google Scholar
Southgate, V.R., Rollinson, D., Ross, G.C., Knowles, R.J. & Vercruysse, J. (1985) On Schistosoma curassoni, S. haematobium, and S. bovis from Senegal: development in Mesocricetus auratus, compatibility with species of Bulinus and their enzymes. Journal of Natural History 19, 1249–1267.Google Scholar
Stelma, F.F., Talla, I., Verlé, P., Niang, M. & Gryseels, B. (1994) Morbidity due to heavy Schistosoma mansoni infections in a recently established focus in northern Senegal. American Journal of Tropical Medicine and Hygiene 50, 575–579.Google Scholar
Stelma, F.F., Talla, I., Kongs, A., Niang, M., Polman, K., Deelder, A.M. & Gryseels, B. (1995) Efficacy and side effects of praziquantel in an epidemic focus of Schistosoma mansoni. American Journal of Tropical Medicine and Hygiene 53, 167–170.Google Scholar
Stelma, F.F., Werf, M.V.D., Talla, I., Niang, M. & Gryseels, B. (in press) Four years follow-up of hepatosplenic mobidity in a recently emerged focus of Schistosoma mansoni in northern Senegal. Transactions of the Royal Society of Tropical Medicine and Hygiene.Google Scholar
Talla, I., Kongs, A., Verlé, P., Belot, J., Sarr, S. & Coll, A.M. (1990) Outbreak of intestinal schistosomiasis in the Senegal River Basin. Annales de la Societé Belge de Médecine Tropicale 70, 173–180.Google Scholar
Talla, I., Kongs, A. & Verlé, P. (1992) Preliminary study of the prevalence of human schistosomiasis in Richard-Toll (the Senegal river basin). Transactions of the Royal Society of Tropical Medicine and Hygiene 86, 132.CrossRefGoogle ScholarPubMed
TDR News (World Health Organization) (1996) Schistosomiasis vaccine: an update. 50, 8–9.Google Scholar
Vercruysse, J., Southgate, V.R. & Rollinson, D. (1985) The epidemiology of human and animal schistosomiasis in the Senegal River Basin. Acta Tropica 42, 249–259.Google Scholar
Vercruysse, J., Southgate, V.R., Rollinson, D., De Clercq, D., Sacko, M., De Bont, J. & Mungomba, L.M. (1994) Studies on transmission and schistosome interactions in Senegal, Mali and Zambia. Tropical and Geographical Medicine 46, 220–226.Google ScholarPubMed
Verlé, P., Stelma, F., Desreumaux, P., Dieng, A., Diaw, O., Kongs, A., Niang, M., Sow, S., Talla, I., Sturrock, R.F., Gryseels, B. & Capron, A. (1994) Preliminary study of urinary schistosomiasis in a village in the delta of the Senegal river basin, Senegal. Transactions of the Royal Society of Tropical Medicine and Hygiene 88, 401–405.CrossRefGoogle Scholar
Wash Field Report No. 453 (1994) Senegal River Basin Health Master Plan. 163 pp. Prepared for the USAID Mission to Senegal under WASH Task No. 512.Google Scholar
White, N.J. & Olliaro, P.L. (1996) Strategies for the prevention of antimalarial drug resistance: rationale for combination chemotherapy for malaria. Parasitology Today 12, 399–340.CrossRefGoogle ScholarPubMed