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Head and neck tumour immunology: basic concepts and new clinical implications

Published online by Cambridge University Press:  02 September 2008

K P Topping ,
L M Fletcher ,
F O Agada ,
O Alhamarneh ,
N D Stafford  and
J Greenman
K P Topping
Affiliation:
Division of Cancer, Department of Otolaryngology, Head and Neck Surgery, Postgraduate Medical Institute, University of Hull, UK
L M Fletcher
Affiliation:
Division of Cancer, Department of Otolaryngology, Head and Neck Surgery, Postgraduate Medical Institute, University of Hull, UK
F O Agada
Affiliation:
Division of Cancer, Department of Otolaryngology, Head and Neck Surgery, Postgraduate Medical Institute, University of Hull, UK
O Alhamarneh
Affiliation:
Division of Cancer, Department of Otolaryngology, Head and Neck Surgery, Postgraduate Medical Institute, University of Hull, UK
N D Stafford
Affiliation:
Division of Cancer, Department of Otolaryngology, Head and Neck Surgery, Postgraduate Medical Institute, University of Hull, UK
J Greenman*
Affiliation:
Division of Cancer, Department of Otolaryngology, Head and Neck Surgery, Postgraduate Medical Institute, University of Hull, UK
*
Address for correspondence: Dr John Greenman, Medical Research Laboratory, University of Hull, Wolfson Building, Cottingham Road, Hull, HU6 7RX, UK. Fax: 01482 466996, E-mail: j.greenman@hull.ac.uk
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Abstract

An understanding of the immune system and its modes of action is fundamental to understanding the causes, natural history, management and treatment of many diseases. As such, a grasp of the principles of immunology is essential for every physician.

This paper represents a succinct overview of the immune system, discussing the major components in turn, in respect of structure, function and integrated organisation, in relation to head and neck cancer.

Keywords

Head and Neck NeoplasmsImmunology
Type
Review Articles
Information
The Journal of Laryngology & Otology , Volume 123 , Issue 1 , January 2009 , pp. 9 - 18
Copyright
Copyright © JLO (1984) Limited 2008

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