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Horner syndrome in glandular fever: a case report

Published online by Cambridge University Press:  06 January 2016

E V West ,
F Sheerin  and
J E H M Bates
E V West*
Affiliation:
Department of Plastic Surgery, Norfolk and Norwich University Hospitals, Norwich, UK
F Sheerin
Affiliation:
Department of Neuroradiology, Oxford University Hospitals NHS Trust, UK
J E H M Bates
Affiliation:
Department of Plastic Surgery, Oxford University Hospitals NHS Trust, UK
*
Address for correspondence: Ms E V West, Department of Plastic Surgery, Norfolk and Norwich University Hospitals, Colney Lane, Norwich NR4 7UY, UK E-mail: emilyvwest@gmail.com
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Abstract

Objective:

This study aimed to present and discuss the case of a patient with known glandular fever who presented with Horner syndrome.

Case report:

A 35-year-old patient with known glandular fever developed acute unilateral Horner syndrome, a previously undescribed complication of this common illness. Magnetic resonance imaging and magnetic resonance angiography showed that enlarged intra-carotid sheath lymphoid tissue was likely to be the underlying cause of sympathetic nerve disruption. The case is described, the anatomy of the sympathetic chain is discussed and possible alternative pathophysiological mechanisms are reviewed.

Conclusion:

This is the first report in the worldwide literature of Horner syndrome arising as a result of compression from enlarged lymph nodes in glandular fever.

Keywords

Horner SyndromeInfectious MononucleosisCaroid Artery
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 130 , Issue 2 , February 2016 , pp. 207 - 209
Copyright
Copyright © JLO (1984) Limited 2016 

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References

1Luzuriaga, K, Sullivan, JL. Infectious Mononucleosis. N Engl J Med 2010;362:1993–2000CrossRefGoogle ScholarPubMed
2Connelly, KP, DeWitt, LD. Neurological complications of infectious mononucleosis. Pediatr Neurol 1994;10:181–4CrossRefGoogle ScholarPubMed
3Odumade, OA, Hogquist, KA, Balfour, HH Jr.Progress and problems in understanding and managing primary Epstein–Barr virus infections. Clin Microbiol Rev 2011;24:193–209CrossRefGoogle ScholarPubMed
4Kedar, S, Biousse, V, Newman, N. Horner's syndrome. UptoDate: Waltham MA, 2012Google Scholar
5Costello, D, Salmon, J, Milford, C, Pretorius, P. A rare cause of Horner Syndrome. J Laryngol Otol 2010;124:925–7CrossRefGoogle ScholarPubMed
6Kong, YX, Wright, G, Pesudovs, K, O'Day, J, Wainer, Z, Weisinger, HS. Horner syndrome. Clin Exp Optom 2007;90:336–44CrossRefGoogle ScholarPubMed
7Wilhelm, H, Ochsner, H, Kopycziok, E, Trauzettel-Klosinski, S, Schiefer, U, Zrenner, E. Horner's syndrome: a retrospective analysis of 90 cases and recommendations for clinical handling. Ger J Ophthalmol 1992;1:96–102Google ScholarPubMed
8Ismail, MH, Hodkinson, HJ, Tuling, B. Horner's syndrome and tuberculosis. A case report. S Afr Med J 1988;74:586–7Google ScholarPubMed
9Mohanaruban, K, Fisher, DJH. A combination of cranial and peripheral nerve palsies in infectious mononucleosis. Postgrad Med J 1986;62:1129–30CrossRefGoogle ScholarPubMed
10Gavin, C, Langan, Y, Hutchinson, M. Cranial and peripheral neuropathy due to Epstein-Barr virus infection Postgrad Med J 1997;73:419–20CrossRefGoogle ScholarPubMed
11Flanagan, P, Hawkins, S, Bryars, J. Infectious mononucleosis with cranial nerve palsies. Ulster Med J 1987;56:69–71Google ScholarPubMed
12Van Baalen, A, Petersen, B, Stephani, U. Infectious mononucleosis and unilateral tongue writhing. Neurology 2006;66:1110CrossRefGoogle ScholarPubMed
13Salazar, A, Martinez, H, Sotelo, J. Ophthalmoplegic polyneuropathy associated with infectious mononucleosis. Ann Neurol 1983;13:219–20CrossRefGoogle ScholarPubMed
14Vucic, S, Palmer, W, Cros, D. Radiculoplexopathy with conduction block caused by acute Epstein-Barr virus infection. Neurology 2005;64;530–2CrossRefGoogle ScholarPubMed
15Dodig, D, Ngo, M, Bailey, D, Bril, V. Brachial plexopathy complicating Epstein-Barr virus infection in an adult. Acta Myol 2010;29:357–9Google ScholarPubMed
16Librach, IM. Ocular symptoms in glandular fever. Br J Ophthalmol 1956;40:619–21CrossRefGoogle ScholarPubMed
17Flaherty, PM, Flynn, JM. Horner syndrome due to carotid dissection. J Emerg Med 2011;41:43–6CrossRefGoogle ScholarPubMed
18Patel, RR, Adam, R, Maldjian, C, Lincoln, CM, Yuen, A, Arneja, A. Cervical carotid artery dissection: current review of diagnosis and treatment. Cardiol Rev 2012;20:145–52CrossRefGoogle ScholarPubMed
19Chan, CC, Paine, M, O'Day, J. Carotid dissection: a common cause of Horner syndrome. Clin Experiment Ophthalmol 2001;29:411–15CrossRefGoogle Scholar
20George, A, Haydar, AA, Adams, WM. Imaging of Horner's syndrome. Clin Radiol 2008;63:499–505CrossRefGoogle ScholarPubMed
21Digre, KB, Smoker, WR, Johnston, P, Tryhus, MR, Thompson, HS, Cox, TA et al. Selective MR imaging approach for evaluation of patients with Horner's syndrome. AJNR Am J Neuroradiol 1992;13:223–7Google ScholarPubMed
22Lee, JH, Lee, HK, Lee, DH, Choi, CG, Kim, SJ, Suh, DC. Neuroimaging strategies for three types of Horner syndrome with emphasis on anatomic location. AJR Am J Roentgenol 2007;188:74–81CrossRefGoogle ScholarPubMed
23Martin, TJ. Horner's syndrome, pseudo-Horner's syndrome, and simple anisocoria. Curr Neurol Neurosci 2007;7:397–406CrossRefGoogle ScholarPubMed
24Reede, DL, Garcon, E, Smoker, WR, Kardon, R. Horner's syndrome: clinical and radiographic evaluation. Neuroimaging Clin N Am 2008;18:369–85CrossRefGoogle ScholarPubMed
25Yoshiura, T, Wu, O, Sorensen, AG. Advanced MR techniques: diffusion MR imaging, perfusion MR imaging, and spectroscopy. Neuroimaging Clin N Am 1999;9:439–53Google ScholarPubMed