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Impact of olfactory dysfunction on quality of life in coronavirus disease 2019 patients: a systematic review

Part of: JLO Coronavirus Collection

Published online by Cambridge University Press:  24 August 2021

J Saniasiaya  and
N Prepageran
J Saniasiaya*
Affiliation:
Department of Otorhinolaryngology, Faculty of Medicine, University of Malaya, Jalan University, Kuala Lumpur, Malaysia
N Prepageran
Affiliation:
Department of Otorhinolaryngology, Faculty of Medicine, University of Malaya, Jalan University, Kuala Lumpur, Malaysia
*
Author for correspondence: Dr Jeyasakthy Saniasiaya, Department of Otorhinolaryngology, Faculty of Medicine, University of Malaya, Jalan University, 50603Kuala Lumpur, Wilayah Persekutuan Kuala Lumpur, Malaysia E-mail: shakthy_18@yahoo.com
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Abstract

Objective

To outline the impact on quality of life in coronavirus disease 2019 patients with olfactory dysfunction.

Methods

Five databases were searched for articles referring to the impact on quality of life in coronavirus disease 2019 patients with olfactory dysfunction. The search was conducted for the period from November 2019 to April 2021. The search was conducted over one month (May 2021).

Results

Four studies that met the objective were included. Altogether, there were 1045 patients. Various questionnaires were used to assess quality of life. Overall, the quality of life deficit affected 67.7 per cent of patients. Quality of life domains investigated include overall quality of life (four studies), food and taste dysfunction (two studies), mental health (two studies), cognitive function (one study), functional outcome (one study) and safety domains (one study).

Conclusion

Quality of life deficit was reported to be 67.7 per cent among coronavirus disease 2019 patients with olfactory dysfunction. The high prevalence of persistent olfactory dysfunction prompts more serious research, as the long-standing consequences of olfactory dysfunction are detrimental.

Keywords

Quality Of LifeOlfactory ImpairmentSmellCOVID-19
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 135 , Issue 11 , November 2021 , pp. 947 - 952
Copyright
Copyright © The Author(s), 2021. Published by Cambridge University Press

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Footnotes

Dr J Saniasiaya takes responsibility for the integrity of the content of the paper

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