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Primary carcinoid tumour of nasal septum

Published online by Cambridge University Press:  02 September 2008

T Galm  and
N Turner
T Galm*
Affiliation:
ENT Department, Walsall Manor Hospital, UK
N Turner
Affiliation:
ENT Department, Walsall Manor Hospital, UK
*
Address for correspondence: Ms T Galm, Walsall Manor Hospital, Moat Road, Walsall WS2 3PS, UK. E-mail: tiragalm@yahoo.com
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Abstract

Objective:

We present the first reported case of primary carcinoid tumour of the nasal septum.

Method:

Case report of our experience of a carcinoid tumour of the nasal septum. We discuss our clinical, radiological and pathological findings.

Result:

An 83-year-old woman presented with a history of left-sided nasal blockage. Clinical examination showed a unilateral, left-sided nasal polyp. Further imaging and histological analysis confirmed this to be a carcinoid tumour. Carcinoid tumours outside the gastrointestinal tract are rare. There have been reports of carcinoid tumours in the head and neck region, but no published cases occurring in the nasal septum. Our management involved wide surgical resection with regular follow up to monitor for recurrence and for the development of carcinoid syndrome. Four years from initial presentation, the patient remained free of the primary tumour and had displayed no signs or symptoms suggestive of carcinoid syndrome.

Conclusion:

To the authors' best knowledge, and after searching the world literature, the presented case represents the first report of primary carcinoid tumour of the nasal septum. Despite its rarity, this tumour should be considered as part of the differential diagnosis, as timely recognition and intervention are critical for successful treatment.

Keywords

Nasal SeptumCarcinoid TumourHistology
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 123 , Issue 7 , July 2009 , pp. 789 - 792
Copyright
Copyright © JLO (1984) Limited 2008

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References

1 Gapany-Gapanavicius, B, Kenan, S. Carcinoid tumour of the larynx. Ann Otol Rhinol Laryngol 1981;90:42–7CrossRefGoogle Scholar
2 Kidd, M, Modlin, IM, Shapiro, MD. Primary carcinoid tumour of the parotid gland: a case report and review of literature. Ear Nose Throat J 2006;8:533–9Google Scholar
3 Kodama, H, Takezawa, H, Suzuki, T, Kobayashi, K, Kataura, A, Wakabayashi, J et al. Carcinoid tumour of the middle ear. J Laryngol Otol 1989;103:86–91CrossRefGoogle ScholarPubMed
4 Lubarsch, O. Regarding the primary cancer of the ileum, together with remarks about the concurrent occurrence of cancer and tuberculosis [in German]. Virchows Arch 1888;111:280–317CrossRefGoogle Scholar
5 Oberndorfer, S. Carcinoid tumour of the small intestines [in German]. Frankf Z Pathol 1907;1:425–9Google Scholar
6 Modlin, IM, Lye, KD, Kidd, M. A 5 decade analysis of 13,715 carcinoid tumours. Cancer 2003;97:934–59CrossRefGoogle Scholar
7 Williams, ED, Sandler, M. The classification of carcinoid tumours. Lancet 1963;i:238–9CrossRefGoogle Scholar
8 Wenig, BM, Hymans, VJ, Heffner, DK. Moderately differentiated neuroendocrine carcinoma of the larynx. A clinicopathologic study of 54 cases. Cancer 1988;62;2658–763.0.CO;2-M>CrossRefGoogle ScholarPubMed
9 Masaki, I, Tetsuaki, K, Soat, T, Hajime, H, Masahiro, K. Ten cases of malignant tumours of the nasal septum. Practica Otologica 2002;109:54–7Google Scholar
10 Motoori, K, Takano, H, Nakano, K, Yamamoto, S, Ueda, T, Ikeda, M. Pleomorphic adenoma of the nasal septum MR features. Am J Neuroradiol 2000;21:1948–1950Google ScholarPubMed
11 Park, E-H, Lee, S-S, Byun, SW. A schwannoma in the nasal septum. Eur Arch Otorhinolaryngol 2007;24:1434Google Scholar
12 Kulke, MH, Meyer, RJ. Carcinoid tumors. N Engl J Med 1999;340:858–68CrossRefGoogle ScholarPubMed
13 Soga, J, Tazawa, K. Pathologic analysis of carcinoids: histologic reevaluation of 62 cases. Cancer 1971;28:990–83.0.CO;2-K>CrossRefGoogle ScholarPubMed
14 Bax, ND, Woods, HF, Batchelor, A, Jennings, M. Clinical manifestation of carcinoid disease. World J Surg 1996;20:142–6CrossRefGoogle ScholarPubMed
15 Hope, RA, Longmore, JM, McManus, SK, Wood-Allum, CA. Oxford Handbook of Clinical Medicine. Oxford: Oxford University Press, 1998Google Scholar
16 Wessels, FJ, Schell, SR. Radiofrequency ablation treatment of refractory carcinoid hepatic metastases. J Surg Res 2001;95:8–12CrossRefGoogle ScholarPubMed
17 Que, FG, Nagorney, DM, Batts, KP, Linz, LJ, Kvols, LK. Hepatic resection for metastatic neuroendocrine carcinomas. Am J Surg 1995;169:36–43CrossRefGoogle ScholarPubMed
18 McEntee, GP, Nagorney, DM, Kvols, LK, Moertel, CG, Grant, CS. Cytoreductive hepatic surgery for neuroendocrine tumors. Surgery 1990;108:1091–6Google ScholarPubMed
19 Dousset, B, Saint-Marc, O, Pitre, J, Soubrane, O, Houssin, D, Chapuis, Y. Metastatic neuroendocrine tumors: medical treatment, surgical resection, or liver transplantation. World J Surg 1996;20:908–15CrossRefGoogle ScholarPubMed
20 Rougier, P, Mitry, E. Chemotherapy in the treatment of neuroendocrine malignant tumors. Digestion 2000;62:73–8CrossRefGoogle ScholarPubMed
21 Horton, KM, Kamel, I, Hofmann, L, Fishman, EK. Carcinoid tumors of the small bowel: a multitechnique imaging approach. AJR Am J Roentgenol 2004;182:559–67CrossRefGoogle ScholarPubMed