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Rhinocerebral mucormycosis with orbital and intracranial extension: a case report and review of optimum management

Published online by Cambridge University Press:  30 November 2006

N Munir  and
N S Jones
N Munir
Affiliation:
Department of Otorhinolaryngology and Head & Neck Surgery, Queen's Medical Centre, Nottingham, UK.
N S Jones
Affiliation:
Department of Otorhinolaryngology and Head & Neck Surgery, Queen's Medical Centre, Nottingham, UK.
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Abstract

Rhinocerebral mucormycosis is a devastating, rapidly progressive and often fatal opportunistic fungal infection predominantly affecting individuals with underlying metabolic and/or immunological compromise. Intracranial extension of the disease has invariably been associated with mortality.

We present a review of optimum management of rhinocerebral mucormycosis and a case report of sinonasal mucormycosis with intracranial and orbital extension which was treated successfully with a combination of systemic liposomal amphotericin B therapy and wide surgical debridement.

Keywords

MucormycosisSinusitisIntracranial Infection
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 121 , Issue 2 , February 2007 , pp. 192 - 195
Copyright
2006 JLO (1984) Limited

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