Hostname: page-component-78c5997874-g7gxr Total loading time: 0 Render date: 2024-11-14T08:31:14.926Z Has data issue: false hasContentIssue false
  • English
  • Français

Small cell neuroendocrine carcinoma of the nasal cavity and paranasal sinuses: a rare case

Published online by Cambridge University Press:  19 October 2012

I P Tang ,
S Singh ,
G Krishnan  and
L M Looi
I P Tang*
Affiliation:
Otorhinolaryngology Department, Faculty of Medicine, University of Malaysia, Sarawak, Malaysia
S Singh
Affiliation:
Otorhinolaryngology Department, Faculty of Medicine, University of Malaya, Malaysia
G Krishnan
Affiliation:
Otorhinolaryngology Department, Faculty of Medicine, University of Malaya, Malaysia
L M Looi
Affiliation:
Pathology Department, Faculty of Medicine, University of Malaya, Malaysia
*
Address for correspondence: Dr I P Tang, 66 Lorong Setia Raja 12A1, Taman Stutong Indah, 93350 Kuching, Sarawak, Malaysia Fax: +6082 422 564 E-mail: ingptang@yahoo.com
Get access Rights & Permissions [Opens in a new window]

Abstract

Objective:

We report a rare case of small cell neuroendocrine carcinoma of the nasal cavity and paranasal sinuses with intracranial extension, and discuss the management of this rare tumour.

Results:

Small cell neuroendocrine carcinoma involving the nasal cavity and paranasal sinuses with intracranial extension may be treated successfully with surgery alone, without development of local recurrence.

Conclusion:

Small cell neuroendocrine carcinoma is a locally aggressive tumour with a high rate of recurrence. Early and aggressive surgical excision with or without radiotherapy or chemotherapy can improve a patient's outcome and prognosis. Regular follow up is needed to detect any local or distant recurrence.

Keywords

Carcinoma, Small CellNeuroendocrine TumoursNasal CavityParanasal Sinuses
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 126 , Issue 12 , December 2012 , pp. 1284 - 1286
Copyright
Copyright © JLO (1984) Limited 2012

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1Ibrahim, NB, Briggs, JC, Corbishley, CM. Extrapulmonary oat cell carcinoma. Cancer 1984;54:1645–613.0.CO;2-Q>CrossRefGoogle ScholarPubMed
2Koss, LG, Spiro, RH, Hajdu, S. Small cell carcinoma of minor salivary gland origin. Cancer 1972;30:737–413.0.CO;2-M>CrossRefGoogle ScholarPubMed
3Babin, E, Rouleau, V, Vedrine, PO, Toussaint, B, de Raucourt, D, Malard, O et al. Small cell neuroendocrine carcinoma of the nasal cavity and paranasal sinuses. J Laryngol Otol 2006;120:289–97CrossRefGoogle ScholarPubMed
4Rejowski, JE, Campanella, RS, Block, LJ. Small cell carcinoma of the nose and paranasal sinuses. Otolaryngol Head Neck Surg 1982;90:516–17CrossRefGoogle ScholarPubMed
5Mineta, H, Miura, K, Takebayashi, S, Araki, K, Ueda, Y, Harada, H et al. Immunohistochemical analysis of small cell carcinoma of the head and neck: a report of four patients and review of sixteen patients in the literature with ectopic hormone production. Ann Otol Rhinol Laryngol 2001;110:76–82CrossRefGoogle ScholarPubMed
6Smith, SR, Som, P, Fahmy, A, Lawson, W, Sacks, S, Brandwein, M. A clinicopathological study of sinonasal neuroendocrine carcinoma and sinonasal undifferentiated carcinoma. Laryngoscope 2000;110:1617–22CrossRefGoogle ScholarPubMed
7Soussi, AC, Benghiat, A, Holgate, CS, Majumdar, B. Neuro-endocrine tumours of the head and neck. J Laryngol Otol 1990;104:504–7CrossRefGoogle ScholarPubMed