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Thyroid involvement by laryngeal cancer among Iranian patients

Published online by Cambridge University Press:  27 March 2013

B Naghibzadeh ,
E Razmpa ,
N Amiri ,
GH Naghibzadeh  and
F Bandarian
B Naghibzadeh
Affiliation:
Department of Otolaryngology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
E Razmpa*
Affiliation:
Department of Otolaryngology, Tehran University of Medical Sciences, Tehran, Iran
N Amiri
Affiliation:
Department of Oncology, Kermanshah University of Medical Sciences, Kermanshah, Iran
GH Naghibzadeh
Affiliation:
School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
F Bandarian
Affiliation:
Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran Farzan Clinical Research Institute, Tehran, Iran
*
Address for correspondence: Dr Ebrahim Razmpa, PO Box 13185-1678, Tehran, Iran Fax: +9821 66423304 E-mail: swt_f@yahoo.com
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Abstract

Objective:

Asian patients with laryngeal cancer have been reported to have a high prevalence of thyroid involvement. This study aimed to investigate the prevalence of thyroid invasion in Iranian patients with laryngeal cancer.

Methods:

Hospital records for all patients with a definite diagnosis of laryngeal cancer between 1996 and 2009 (351 patients) were reviewed, and the prevalence of thyroid invasion was established based on the pathology report at the time of surgery.

Results:

Thyroid invasion was found in 16 patients (4.55 percent), and was limited to one thyroid lobe in two-thirds of cases. All instances of thyroid invasion occurred in patients with stage III (81.25 percent) or IV (18.75 percent) cancer. No case of metastasis was reported. The glottic region was identified as the tumour origin in most cases of thyroid invasion (56.25 percent).

Conclusion:

Most cases of thyroid invasion by laryngeal cancer occurred in cancer stage III, at grades G1 and G2, among male patients, and arose from tumours of the glottic region.

Keywords

Laryngeal NeoplasmsCarcinomaIranThyroidPathologyNeoplasm GradingNeoplasm Staging
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 127 , Issue 5 , May 2013 , pp. 501 - 504
Copyright
Copyright © JLO (1984) Limited 2013 

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