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Adverse effects of nasal continuous positive airway pressure therapy in sleep apnoea syndrome

Published online by Cambridge University Press:  29 June 2007

A. Kalan ,
G. S. Kenyon ,
T. A. R. Seemungal  and
J. A. Wedzicha
A. Kalan*
Affiliation:
Department of Otolaryngology and Academic Department of Respiratory Medicine St. Bartholomew's and Royal London School of Medicine and Dentistry, London, UK
G. S. Kenyon
Affiliation:
Department of Otolaryngology and Academic Department of Respiratory Medicine St. Bartholomew's and Royal London School of Medicine and Dentistry, London, UK
T. A. R. Seemungal
Affiliation:
Department of Otolaryngology and Academic Department of Respiratory Medicine St. Bartholomew's and Royal London School of Medicine and Dentistry, London, UK
J. A. Wedzicha
Affiliation:
Department of Otolaryngology and Academic Department of Respiratory Medicine St. Bartholomew's and Royal London School of Medicine and Dentistry, London, UK
*
Address for correspondence: Mr A. Kalan F.R.C.S. (Ed.), 11 Arrowhead Court, James Lane, Leytonstone, London Ell INT. Fax: 0181 558 3134 e-mail: ak@kalanl.demon.co.uk
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Abstract

Nasal continuous positive airway pressure (nCPAP) is now the treatment of choice for patients with sleep apnoea syndrome. Side-effects and adverse reactions have been described in isolated reports with this device. We have, therefore, systematically studied the side-effects of nCPAP therapy in 300 consecutive patients referred to the London Chest Hospital Ventilatory Support Unit. Ninety-six per cent of patients complained of at least one side-effect resulting from the therapy, with 45 per cent complaining of a side-effect specific to the nasal mask. There was no correlation between the side-effects and level of pressure used during nCPAP. The rate of compliance remained high in spite of the side-effects, with a daily use of 7.8 hours (SD 8.05) and with 83 per cent of the patients using the device every night. Although nCPAP treatment remains acceptable to most patients there exists a high incidence of adverse effects.

Keywords

Sleep apnoea syndromes
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 113 , Issue 10 , October 1999 , pp. 888 - 892
Copyright
Copyright © JLO (1984) Limited 1999

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